Catalog No.
YXX53601
Expression system
E. coli
Species
Plasmodium falciparum (malaria parasite P. falciparum)
Protein length
Glu576-Pro745
Predicted molecular weight
22.87 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q25733
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PfEMP1 variant 1 of strain MC, MCvar-1 PfEMP1, Plasmodium falciparum (malaria parasite P. falciparum)
Plasmodium falciparum expresses fewer var genes at lower levels during asymptomatic dry season infections than clinical malaria cases., PMID:40493675
The role of periostin (OSF-2) in the cytoadherence phenomena mediated by malaria parasites., PMID:40433670
Var genes, strain hyperdiversity, and malaria transmission dynamics., PMID:40393890
Immune evasion runs in the family: two surface protein families of Plasmodium falciparum-infected erythrocytes., PMID:40112571
In vitro evaluation of multi-protein chimeric antigens in effectively clearing the blood stage of Plasmodium falciparum., PMID:40037124
Evasive mechanisms of human VSG and PfEMP1 antigens with link to Vaccine scenario: a review., PMID:39975623
Choice of Drug for Malaria Prevention During Pregnancy Does Not Affect Infant Serologic Responses to Plasmodium falciparum Erythrocyte Membrane Proteins 1., PMID:39963702
A Potential Regulatory Network of Selected Human Erythrocytic miRNAs with Plasmodium falciparum 3D7 mRNAs: A Computational Analysis., PMID:39950472
A paradoxical population structure of var DBLα types in Africa., PMID:39903780
Genome-wide gene expression profiles throughout human malaria parasite liver stage development in humanized mice., PMID:39891010
The impact of intermittent preventive treatment in school aged children with dihydroartemisinin piperaquine and artesunate amodiaquine on IgG response against six blood stage Plasmodium falciparum antigens., PMID:39883707
Ectopic overexpression of Plasmodium falciparum DNA-/RNA-binding Alba proteins misregulates virulence gene homeostasis during asexual blood development., PMID:39868986
A Systematic Targeted Genetic Screen Identifies Proteins Involved in Cytoadherence of the Malaria Parasite P. falciparum., PMID:39829323
Variable surface antigen expression, virulence, and persistent infection by Plasmodium falciparum malaria parasites., PMID:39807932
Identification of novel PfEMP1 variants containing domain cassettes 11, 15 and 8 that mediate the Plasmodium falciparum virulence-associated rosetting phenotype., PMID:39804943
Acquisition of Fc-afucosylation of PfEMP1-specific IgG is age-dependent and associated with clinical protection against malaria., PMID:39747065
Fc-Afucosylation of VAR2CSA-Specific Immunoglobulin G and Clinical Immunity to Placental Plasmodium falciparum Malaria., PMID:39585195
Broadly inhibitory antibodies to severe malaria virulence proteins., PMID:39567685
Differences in phenotype between long-lived memory B cells against Plasmodium falciparum merozoite antigens and variant surface antigens., PMID:39466842
The Plasmodium falciparum histone methyltransferase PfSET10 is dispensable for the regulation of antigenic variation and gene expression in blood-stage parasites., PMID:39445826
Antibodies to specific domains of Plasmodium falciparum erythrocyte membrane protein-1 and its relationship with protection from severe malarial anemia: A prospective study among Ghanaian children., PMID:39385763
A systems serology approach to identifying key antibody correlates of protection from cerebral malaria in Malawian children., PMID:39267089
Children with hemoglobin C or S trait have low serologic responses to a subset of malaria variant surface antigens., PMID:39216830
Hybrid Diffusion Model for Stable, Affinity-Driven, Receptor-Aware Peptide Generation., PMID:39193724
Antibodies to PfEMP1 and variant surface antigens: Protection after controlled human malaria infection in semi-immune Kenyan adults., PMID:39182654
PfEMP1 and var genes - Still of key importance in Plasmodium falciparum malaria pathogenesis and immunity., PMID:39095112
Mosaic and cocktail capsid-virus-like particle vaccines for induction of antibodies against the EPCR-binding CIDRα1 domain of PfEMP1., PMID:39046960
Extracellular Proteomic Profiling from the Erythrocytes Infected with Plasmodium Falciparum 3D7 Holds Promise for the Detection of Biomarkers., PMID:39009910
Variable Surface Antigens of Plasmodium falciparum: Protein Families with Divergent Roles., PMID:38910420
Detection of naturally acquired, strain-transcending antibodies against rosetting Plasmodium falciparum strains in humans., PMID:38842304
Skeleton binding protein 1 localizes to the Maurer's cleft and interacts with PfHSP70-1 and PfHSP70-x in Plasmodium falciparum gametocyte-infected erythrocytes., PMID:38331312
Broadly inhibitory antibodies against severe malaria virulence proteins., PMID:38328068
Betulinic and ursolic acids from Nauclea latifolia roots mediate their antimalarial activities through docking with PfEMP-1 and PfPKG proteins., PMID:38326823
Glycophorin B-PfEMP1 interaction mediates robust rosetting in Plasmodium falciparum., PMID:38309398
A novel computational pipeline for var gene expression augments the discovery of changes in the Plasmodium falciparum transcriptome during transition from in vivo to short-term in vitro culture., PMID:38270586
Single cell transcriptional changes across the blood stages of artemisinin resistant K13580Y Plasmodium falciparum upon dihydroartemisinin exposure., PMID:38105992
Profiles of global mutations in the human intercellular adhesion molecule-1 (ICAM-1) shed light on population-specific malaria susceptibility., PMID:38093209
Different PfEMP1-expressing Plasmodium falciparum variants induce divergent endothelial transcriptional responses during co-culture., PMID:38033133
Cryo-electron microscopy of IgM-VAR2CSA complex reveals IgM inhibits binding of Plasmodium falciparum to Chondroitin Sulfate A., PMID:37828011
Profiling the Plasmodium falciparum Erythrocyte Membrane Protein 1-Specific Immununoglobulin G Response Among Ghanaian Children With Hemoglobin S and C., PMID:37804095
Host receptor binding induces conformational changes in a PfEMP1 protein., PMID:37802029
Natural immunity to malaria preferentially targets the endothelial protein C receptor-binding regions of PfEMP1s., PMID:37791774
PerTurboID, a targeted in situ method reveals the impact of kinase deletion on its local protein environment in the cytoadhesion complex of malaria-causing parasites., PMID:37737226
High-Throughput Antibody Profiling Identifies Targets of Protective Immunity against P. falciparum Malaria in Thailand., PMID:37627332
Endothelial protein C receptor binding induces conformational changes to severe malaria-associated group A PfEMP1., PMID:37582356
Novel secretory organelles of parasite origin - at the center of host-parasite interaction., PMID:37518819
Knobs, Adhesion, and Severe Falciparum Malaria., PMID:37505649
Antibody to Plasmodium falciparum Variant Surface Antigens, var Gene Transcription, and ABO Blood Group in Children With Severe or Uncomplicated Malaria., PMID:37341543
PfAP2-MRP DNA-binding protein is a master regulator of parasite pathogenesis during malaria parasite blood stages., PMID:37293082
Genetic diversity of Plasmodium falciparum erythrocyte membrane protein 1 in field isolates from central Myanmar., PMID:37170461
For research use only. Not for human or drug use.
