Catalog No.
YHD90001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro2-Asp326
Predicted molecular weight
52.14 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P30542
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ADORA1, Adenosine receptor A1
Overexpression of high affinity Type I adenosine receptors promotes the growth of uterine leiomyomas., PMID:40489662
Inhibiting ADORA1 enhances glioma apoptosis and increases its sensitivity to anti-PD1 therapy., PMID:40376586
Identification of key aroma compounds contributing to the pleasurable sensory experience of white Peony tea using GC-MS, computational modeling, and sensory evaluation., PMID:40263863
Baicalin alleviates lipid accumulation in adipocytes via inducing metabolic reprogramming and targeting Adenosine A1 receptor., PMID:40188992
Activation ADORA1 protects against sepsis-associated acute kidney injury by inhibiting pyroptosis., PMID:40090281
Abnormal purine metabolism in nasal epithelial cells affects allergic rhinitis by regulating Th17/Treg cells., PMID:39970135
Clinico-genetic Analysis of Adenosine Signaling Pathway in Drug-Resistant Epilepsy., PMID:39951024
Therapeutic Efficacy of Intermittent Ketogenesis in Modulating Adenosine Metabolism, Immune Response, and Seizure Severity in Refractory Temporal Lobe Epilepsy: A Pilot Human Study., PMID:39920557
Unveiling the substantial role of rutin in the management of drug-induced nephropathy using network pharmacology and molecular docking., PMID:39733639
[Molecular mechanism of Xiangsha Liujunzi Decoction in treating chronic atrophic gastritis based on transcriptome sequencing technology]., PMID:39701680
Dephosphorylation-related signature predicts the prognosis of papillary renal cell carcinoma., PMID:39697703
Characterising a Novel Therapeutic Target for Psoriasis, TYK2, Using Functional Genomics., PMID:39684939
Regulation of NHE3 subcellular localization in epididymal principal cells: pH, cyclic adenosine 3,5 monophosphate (cAMP), and adenosine signaling., PMID:39663831
Muscle tissue transcriptome of F1 Angus-Nellore bulls and steers feedlot finished: impacts on intramuscular fat deposition., PMID:39633259
Adenosine relaxes vagina smooth muscle through the cyclic guanosine monophosphate- and cyclic guanosine monophosphate-dependent pathways., PMID:39611580
The association of gene polymorphisms of adenosine and dopamine receptors with the response to caffeine citrate treatment in infants with apnea of prematurity: a prospective nested case-control study., PMID:39468580
Introduction of a single-nucleotide variant, rs16851030, into the ADORA1 gene increased cellular susceptibility to hypoxia., PMID:39440484
Ultrasonic-assisted synthesis and antitumor evaluation of novel variant heterocyclic compounds based on piperidine ring., PMID:39301894
Effects of Ketogenic Diet on Increased Ethanol Consumption Induced by Social Stress in Female Mice., PMID:39275131
Role of sphingolipid metabolism signaling in a novel mouse model of renal osteodystrophy based on transcriptomic approach., PMID:39149978
Adenosine kinase protects against acetaminophen-induced acute liver injury by activating autophagy in hepatocytes., PMID:39060559
Antidepressant effects of selective adenosine receptor antagonists targeting the A1 and A2A receptors administered jointly with NMDA receptor ligands: behavioral, biochemical and molecular investigations in mice., PMID:39048810
Network Pharmacology Analysis of the Potential Pharmacological Mechanism of a Sleep Cocktail., PMID:38927034
Analgesic candidate adenosine A 3 receptors are expressed by perineuronal peripheral macrophages in human dorsal root ganglion and spinal cord microglia., PMID:38691673
Exploring the Constituents and Mechanisms of Polygonum multiflorum Thunb. in Mitigating Ischemic Stroke: A Network Pharmacology and Molecular Docking Study., PMID:38623977
Intrinsic ecto-5'-Nucleotidase/A1R Coupling may Confer Neuroprotection to the Cerebellum in Experimental Autoimmune Encephalomyelitis., PMID:38619745
Adora2A downregulation promotes caffeine neuroprotective effect against LPS-induced neuroinflammation in the hippocampus., PMID:38494098
Beyond the Nucleus: Plastic Chemicals Activate G Protein-Coupled Receptors., PMID:38440973
Elucidating the role of intrinsic adenosine A1 receptors in acute alcoholism using human-induced pluripotent stem cell-derived hepatocytes., PMID:38419509
Enhancing spinal cord stimulation-induced pain inhibition by augmenting endogenous adenosine signalling after nerve injury in rats., PMID:38310069
Inhibitory effect of truncated isoforms on GPCR dimerization predicted by combinatorial computational strategy., PMID:38173876
Waste to Medicine: Evidence from Computational Studies on the Modulatory Role of Corn Silk on the Therapeutic Targets Implicated in Type 2 Diabetes Mellitus., PMID:38132335
Gene expression changes in conjunctival cells associated with contact lens wear and discomfort., PMID:38128761
Multi-Functional Small Molecule Alleviates Fracture Pain and Promotes Bone Healing., PMID:37939302
Synthesis, Computational, and Anticancer In Vitro Investigations of Aminobenzylnaphthols Derived from 2-Naphtol, Benzaldehydes, and α-Aminoacids via the Betti Reaction., PMID:37894709
Ultrasonic-induced synthesis of novel diverse arylidenes via Knoevenagel condensation reaction. Antitumor, QSAR, docking and DFT assessment., PMID:37822658
Symptom-oriented network pharmacology revealed the mechanism of HuangQi-DanShen herb pair against cerebral ischemia coupled with comprehensive chemical characterization., PMID:37437791
A novel extrachromosomal circular DNA related genes signature for overall survival prediction in patients with ovarian cancer., PMID:37337170
Up- and Downregulated Genes after Long-Term Muscle Atrophy Induced by Denervation in Mice Detected Using RNA-Seq., PMID:37240756
The resurgence of the Adora2b receptor as an immunotherapeutic target in pancreatic cancer., PMID:37187740
Tau pathology epigenetically remodels the neuron-glial cross-talk in Alzheimer's disease., PMID:37083538
Integrative transcriptomics analysis and experimental validation reveal immunomodulatory patterns in keratoconus., PMID:37001853
Elucidation of the Landscape of Alternatively Spliced Genes and Features in the Dorsal Striatum of Aggressive/Aggression-Deprived Mice in the Model of Chronic Social Conflicts., PMID:36980872
Anti-Inflammatory Effect of Caffeine on Muscle under Lipopolysaccharide-Induced Inflammation., PMID:36978802
Integrative genetics-metabolomics analysis of infant bronchiolitis-childhood asthma link: A multicenter prospective study., PMID:36818476
Microglial depletion exacerbates motor impairment and dopaminergic neuron loss in a 6-OHDA model of Parkinson's disease., PMID:36681049
RNA-seq reveals that anti-obesity irisin and triiodothyronine (T3) hormones differentially affect the purinergic signaling transcriptomics in differentiated human adipocytes., PMID:36642213
The ADORA1 mutation linked to early-onset Parkinson's disease alters adenosine A1-A2A receptor heteromer formation and function., PMID:36279718
Novel active compounds and the anti-diabetic mechanism of mulberry leaves., PMID:36278175
Study on the mechanism of anti-acute lung injury of Shuanghuanglian oral liquid based on identification of transitional components in blood and network pharmacology., PMID:36265206