Catalog No.
YHD01801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
[Asp230-Pro277] & [Ser335-Gly380] & [Arg564-Thr643]
Predicted molecular weight
22.70 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P13866
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Solute carrier family 5 member 1, SLC5A1, High affinity sodium-glucose cotransporter, SGLT1, Sodium/glucose cotransporter 1, Na(+)/glucose cotransporter 1, NAGT
Hypoglycemic potential of sugarcane molasses-derived polyphenols: exploring the hypoglycemic mechanisms through in vitro α-glucosidase inhibition and intracellular glucose transport inhibition., PMID:40390634
CLK2-SOX3 combination promotes choroidal neovascularization by SGLT1 inducing endothelial cell metabolic reprogramming., PMID:40373839
Luminal Sweet Sensing and Enteric Nervous System Participate in Regulation of Intestinal Glucose Transporter, GLUT2., PMID:40362862
A Novel, Multifunctional Resistant Starch-Phenol Complex with Potential for Better Glycemic Control., PMID:40263306
Comprehensive analysis of glycometabolism-related genes reveals PLOD2 as a prognostic biomarker and therapeutic target in gastric cancer., PMID:40229676
Glucose absorption by isolated, vascularly perfused rat intestine: A significant paracellular contribution augmented by SGLT1 inhibition., PMID:40186371
Effects of microencapsulated essential oils and seaweed meal on growth performance, digestive enzymes, intestinal morphology, liver functions, and plasma biomarkers in broiler chickens., PMID:40151066
Acute tuft cell ablation in mice induces malabsorption and alterations in secretory and immune cell lineages in the small intestine., PMID:40051209
Estrogen-Driven Maintenance of GLUT1/GLUT4/SGLT1 under glucose starvation drives energy homeostasis in bovine PMNs., PMID:40043818
Comparing glucose acquisition strategies between two ancient fish species: Lake sturgeon (Acipenser fulvescens) and North Pacific spiny dogfish (Squalus suckleyi)., PMID:39988024
Molecular characterization and function of sodium-dependent glucose transporter 1 in postprandial glucose homeostasis in Macrobrachium rosenbergii., PMID:39921081
The role of SGLT1 in atrial fibrillation and its relationship with endothelial-mesenchymal transition., PMID:39823893
The effect of carbohydrates with different levels of digestibility on energy metabolism in vivo under hypobaric hypoxic conditions., PMID:39779022
Immunolocalization of sodium-dependent glucose co-transporter 1 and sodium-dependent glucose co-transporter 2 in chicken's (Gallus gallus domesticus) kidneys., PMID:39736118
Investigation of glucosuria in children., PMID:39651934
Single-cell transcriptomics of human organoid-derived enteroendocrine cell populations from the small intestine., PMID:39639676
Transcriptomics of SGLT2-positive early proximal tubule segments in mice: response to type 1 diabetes, SGLT1/2 inhibition, or GLP1 receptor agonism., PMID:39589189
Sodium-dependent glucose co-transport proteins (SGLTs) are not involved in human glucose taste detection., PMID:39556551
Uninephrectomy and sodium-glucose cotransporter 2 inhibitor administration delay the onset of hyperglycemia., PMID:39523534
Synthesis of a Small Library of Glycoderivative Putative Ligands of SGLT1 and Preliminary Biological Evaluation., PMID:39519708
The Benefits of Whole-Exome Sequencing in the Differential Diagnosis of Hypophosphatasia., PMID:39519277
The Impact of SGLT1 Inhibition on Frailty and Sarcopenia: A Mediation Mendelian Randomization Study., PMID:39474649
Regulation of Enterocyte Brush Border Membrane Primary Na-Absorptive Transporters in Human Intestinal Organoid-Derived Monolayers., PMID:39404387
SGLT1 inhibition alleviates radiation-induced intestinal damage through promoting mitochondrial homeostasis., PMID:39393555
Duodenal-Jejunal Bypass Restores Sweet Taste Receptor-Mediated Glucose Sensing and Absorption in Diabetic Rats., PMID:39263491
Salmon Milt Extract Suppresses Glucose Uptake by Downregulating SGLT1 and GLUT2 Expression in Caco-2 Cells., PMID:39231687
Biophysical Analysis of a Minimalistic Kidney Model Expressing SGLT1 Reveals Crosstalk between Luminal and Lateral Membranes and a Plausible Mechanism of Isosmotic Transport., PMID:39199277
Electroacupuncture regulates glucose metabolism by inhibiting SGLT1 levels, inhibiting microglial polarization, and alleviating Parkinson's disease., PMID:39197673
Dual SGLT1 and SGLT2 inhibitor sotagliflozin achieves FDA approval: landmark or landmine?, PMID:39195959
Quercetin slow-release system delays starch digestion via inhibiting transporters and enzymes., PMID:39167947
Recent Progress and Perspectives in Sodium-Glucose Co-transporter 1/2 Inhibitors., PMID:39162279
Procyanidin B1 and p-coumaric acid from whole highland barley ameliorated HFD-induced impaired glucose tolerance via small intestinal barrier and hepatic glucose metabolism., PMID:39162187
The effect of rs2910686 on ERAP2 expression in IBD and epithelial inflammatory response., PMID:39123229
Nuclear Receptor Corepressors NCOR1 and SMRT Regulate Metabolism via Intestinal Regulation of Carbohydrate Transport., PMID:39106294
SGLT1 contributes to glucose-mediated exacerbation of ischemia-reperfusion injury in ex vivo rat heart., PMID:39088085
Highly Soluble β-Glucan Fiber Modulates Mechanisms of Blood Glucose Regulation and Intestinal Permeability., PMID:39064683
Crucial role for sensory nerves and Na/H exchanger inhibition in dapagliflozin- and empagliflozin-induced arterial relaxation., PMID:39056245
Sodium-glucose cotransporter 1/2 inhibition and risk of neurodegenerative disorders: A Mendelian randomization study., PMID:39010704
Comparative evaluation of the antihyperglycemic effects of three extracts of sea mustard (Undaria pinnatifida): In vitro and in vivo studies., PMID:38945577
Sucrose Solution Ingestion Exacerbates Dinitrofluorobenzene-Induced Allergic Contact Dermatitis in Rats., PMID:38931315
Development of a selective novel fluorescent substrate for sodium-dependent transporters., PMID:38880166
Effects of Three Kinds of Carbohydrate Pharmaceutical Excipients-Fructose, Lactose and Arabic Gum on Intestinal Absorption of Gastrodin through Glucose Transport Pathway in Rats., PMID:38834905
SGLT1 and SGLT2 inhibition, circulating metabolites, and cerebral small vessel disease: a mediation Mendelian Randomization study., PMID:38715111
Intestinal absorption of D-fructose isomers, D-allulose, D-sorbose and D-tagatose, via glucose transporter type 5 (GLUT5) but not sodium-dependent glucose cotransporter 1 (SGLT1) in rats., PMID:38713062
Sodium-glucose cotransporter 1 promotes the biofunctions of perivascular preadipocytes mediated by Akt/mTOR/p70S6K signaling pathway., PMID:38646789
The inflammatory injury of porcine small intestinal epithelial cells induced by deoxynivalenol is related to the decrease in glucose transport., PMID:38619320
Canagliflozin inhibits PASMCs proliferation via regulating SGLT1/AMPK signaling and attenuates artery remodeling in MCT-induced pulmonary arterial hypertension., PMID:38574614
Exploring Bariatric Surgery's Impact on Weight Loss and Diabetes: Sodium and Glucose Receptor Modulation., PMID:38562948
SFXN1-mediated immune cell infiltration and tumorigenesis in lung adenocarcinoma: A potential therapeutic target., PMID:38537539
Sugar binding of sodium-glucose cotransporters analyzed by voltage-clamp fluorometry., PMID:38522518
For research use only. Not for human or drug use.
