Catalog No.
AHJ90101
Biological activity
Measured by its ability to bind hyaluronan in a functional ELISA.
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Ser24-Thr238
Nature
Recombinant
Endotoxin level
<0.1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y5Y7
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cell surface retention sequence-binding protein 1, XLKD1, LYVE-1, Hyaluronic acid receptor, Extracellular link domain-containing protein 1, CRSBP-1, LYVE1, CRSBP1, HAR, Lymphatic vessel endothelial hyaluronic acid receptor 1
Amyloid-beta deposition and reduced drainage at the cribriform plate lymphatics in APP/PS1 mouse model of Alzheimer's Disease., PMID:40475486
Protein interaction network drive more group integrated analytic larynx hub protein markers: LYVE1/FBLN5/INMT/DCN/ZFY/RSPO3 protein macromolecule collaborative diagnosis of a new era., PMID:40419046
Lingguizhugan decoction inhibits the cleavage of LYVE-1 by MMP-9 and promotes lymphangiogenesis to improve myocardial infarction., PMID:40412056
Prox1 Protein in Corneal Limbal Lymphatic Vessels Maintains Limbal Stem Cell Stemness and Regulates Corneal Injury Repair., PMID:40298888
Identification of endocrine disrupting chemicals targeting NTD-related hub genes during pregnancy via in silico analysis., PMID:40187376
Analysis of the (lymph-)angiogenic potential of regenerative scaffolds and the impact of adipose-derived mesenchymal stem cells., PMID:40178869
Lymphatic Activation of ACKR3 Signaling Regulates Lymphatic Response After Ischemic Heart Injury., PMID:40143814
Structure and unusual binding mechanism of the hyaluronan receptor LYVE-1 mediating leucocyte entry to lymphatics., PMID:40113779
Bioactivated scaffolds promote angiogenesis and lymphangiogenesis for dermal regeneration in vivo., PMID:40078220
Photodynamic priming with red light triggers adaptive immune responses in a pancreatic cancer mouse model., PMID:40007355
Tumor cell-derived hyaluronan fragments induce endocytosis of S1PR1 to promote lymphangiogenesis through LYVE-1-Src pathway., PMID:39991586
LYVE1 and IL1RL1 are mitochondrial permeability transition-driven necrosis-related genes in heart failure., PMID:39870162
Collagen deposition in lung parenchyma driven by depletion of interstitial Lyve-1+ macrophages prevents cigarette smoke-induced emphysema and loss of airway function., PMID:39830508
The Transcription Factor SOX18 Inhibitor Small Molecule 4 Is a Potential Treatment of Cancer-Induced Lymphatic Metastasis and Lymphangiosarcoma., PMID:39791369
SLC7A11/xCT-mediated Cystine Uptake Regulates Intracellular Glutathione and Promotes Antioxidant Defense in Lymphatic Endothelial Cells., PMID:39740839
Lyve1-Driven NrasQ61R Causes Edema, Enlarged Lymphatic Vessels, and Hepatic Vascular Defects in Embryonic Mice., PMID:39723841
A Novel in vivo Rat Mesentery Model for Studying Tumor Spheroid-Induced Microvascular Remodeling., PMID:39701053
The role of exercise in promoting lymphangiogenesis and extracellular matrix synthesis in lymphedema-induced tissue injury., PMID:39676093
Lymphovascular Tumoral Emboli in Inflammatory Breast Cancer Result from Haptotaxis-Mediated Encircling Lymphangiogenesis., PMID:39669476
IL-17A/CEBPβ/OPN/LYVE-1 axis inhibits anti-tumor immunity by promoting tumor-associated tissue-resident macrophages., PMID:39643970
Engineering ADSCs by manipulating YAP for lymphedema treatment in a mouse tail model., PMID:39633684
Molecules That Have Rarely Been Studied in Lymphatic Endothelial Cells., PMID:39596293
Macrophages and nociceptor neurons form a sentinel unit around fenestrated capillaries to defend the synovium from circulating immune challenge., PMID:39587345
EphrinB2-mediated CDK5/ISL1 pathway enhances cardiac lymphangiogenesis and alleviates ischemic injury by resolving post-MI inflammation., PMID:39557830
VEGFC Overexpression in Kidney Progenitor Cells Is a Model of Renal Lymphangiectasia-Brief Report., PMID:39540281
A Clinical Laboratory Improvement Amendments/College of American Pathologists-Compliant Noninvasive Laboratory-Developed Test for Early Detection of Pancreatic Ductal Adenocarcinoma., PMID:39521243
Similarities and differences between brain and skin GNAQ p.R183Q driven capillary malformations., PMID:39343803
Distinct activation of M1 and M2 macrophages in the primary pterygium lymphangiogenesis., PMID:39326777
Evaluation of urinary C-reactive protein as an early detection biomarker for pancreatic ductal adenocarcinoma., PMID:39309742
Early intermittent hyperlipidaemia alters tissue macrophages to fuel atherosclerosis., PMID:39231480
Robust Differentiation of Human Pluripotent Stem Cells into Lymphatic Endothelial Cells Using Transcription Factors., PMID:39197437
Urinary biomarkers analysis as a diagnostic tool for early detection of pancreatic adenocarcinoma: Molecular quantification approach., PMID:39159599
[Hyaluronan receptors: role in aging and age-associated processes.]., PMID:39139118
Urine biomarkers can predict prostate cancer and PI-RADS score prior to biopsy., PMID:39103428
Resolving Resident Colonic Muscularis Macrophage Diversity and Plasticity During Colitis., PMID:39102823
Primitive macrophages induce sarcomeric maturation and functional enhancement of developing human cardiac microtissues via efferocytic pathways., PMID:39086373
Connexin-45 is expressed in mouse lymphatic endothelium and required for lymphatic valve function., PMID:39074069
Lymphatic Capillarization in Different Fiber Types of Rat Skeletal Muscles With Growth and Age., PMID:39073171
[Imaging for displaying lymphatic vessels in whole-mount aorta adventitia of ApoE-/- mice by immunofluorescent histochemical staining]., PMID:38952092
Lack of inflammation or immune response in cyst tissue of patients with symptomatic non-hydrocephalic pineal cysts., PMID:38943895
VEGF-C and 5-Fluorouracil Improve Bleb Survival in a Rabbit Glaucoma Surgery Trabeculectomy Model., PMID:38771570
Characterization of perivascular alveolar epithelial stem cells and their niche in lung homeostasis and cancer., PMID:38759645
Low-dose cadmium induces lymphangiogenesis through activation of the STAT3 signaling pathway., PMID:38744218
Hyaluronic Acid as a LYVE-1 Receptor Ligand in the Lymphatic System of Healthy Human Skin., PMID:38727953
LYVE-1-expressing Macrophages Modulate the Hyaluronan-containing Extracellular Matrix in the Mammary Stroma and Contribute to Mammary Tumor Growth., PMID:38717149
Identification of potential targetable genes in papillary, follicular, and anaplastic thyroid carcinoma using bioinformatics analysis., PMID:38676768
Decorin suppresses tumor lymphangiogenesis: A mechanism to curtail cancer progression., PMID:38652741
Tumor microenvironment restricts IL-10 induced multipotent progenitors to myeloid-lymphatic phenotype., PMID:38640116
Examining the correlation of lymphangiogenesis biomarkers with clinical condition in Age-Related Macular Degeneration (AMD)., PMID:38615832
Serum proteomic profiling of patients with compensated advanced chronic liver disease with and without clinically significant portal hypertension., PMID:38603681
For research use only. Not for human or drug use.
