Catalog No.
AHJ85001
Biological activity
Measured by its ability to compete with biotinylated rhAng-2 for binding to immobilized Tie-2 in a functional ELISA. Compared to rmAngiopoietin-3, rhANGPT4 (Cat #: AHJ85001) is less effective in this competitive assay.
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Gln24-Ile503
Nature
Recombinant
Endotoxin level
<0.1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y264
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ANG4, ANG3, ANG-4, ANGPT4, Angiopoietin-3, Angiopoietin-4, ANG-3
Angiopoietin-4 expression and potential mechanisms in carcinogenesis: Current achievements and perspectives., PMID:39294405
Zebrafish ANGPT4, member of fibrinogen-related proteins, is an LTA-, LPS- and PGN-binding protein with a bacteriolytic activity., PMID:38360193
Effects of BPA Exposure and Recovery on the Expression of Genes Involved in the Hepatic Lipid Metabolism in Male Mice., PMID:37755785
Angiopoietin4 (ANGPT4) expression and potential mechanisms in carcinogenesis: current achievements and perspectives., PMID:37659993
Establishment, characterization, and drug screening of low-passage patient individual non-small cell lung cancer in vitro models including the rare pleomorphic subentity., PMID:37228492
Single-cell analysis reveals an Angpt4-initiated EPDC-EC-CM cellular coordination cascade during heart regeneration., PMID:37155312
Long term exposure of cigarette smoke condensate (CSC) mediates transcriptomic changes in normal human lung epithelial Beas-2b cells and protection by garlic compounds., PMID:36758788
Cooperation of Angiopoietin-2 and Angiopoietin-4 in Schlemm's Canal Maintenance., PMID:36190459
The involvement of ACO3 protein in diabetic retinopathy through the PI3k/Akt signaling pathway., PMID:35275447
Distinct Clinical Impact and Biological Function of Angiopoietin and Angiopoietin-like Proteins in Human Breast Cancer., PMID:34685578
The Study of Angptl4-Modulated Podocyte Injury in IgA Nephropathy., PMID:33643055
The Amino-Terminal Oligomerization Domain of Angiopoietin-2 Affects Vascular Remodeling, Mammary Gland Tumor Growth, and Lung Metastasis in Mice., PMID:33037065
Long non-coding RNA linc00665 interacts with YB-1 and promotes angiogenesis in lung adenocarcinoma., PMID:32423800
ERO1α promotes hypoxic tumor progression and is associated with poor prognosis in pancreatic cancer., PMID:31666928
Dual functional nanoparticles containing SOX duo and ANGPT4 shRNA for osteoarthritis treatment., PMID:30957437
Angiopoietin-4-dependent venous maturation and fluid drainage in the peripheral retina., PMID:30444491
Genome-wide association study and meta-analysis in multiple populations identifies new loci for peanut allergy and establishes C11orf30/EMSY as a genetic risk factor for food allergy., PMID:29030101
Expression of Biglycan in First Trimester Chorionic Villous Sampling Placental Samples and Altered Function in Telomerase-Immortalized Microvascular Endothelial Cells., PMID:28408374
Effects of low level laser therapy on inflammatory and angiogenic gene expression during the process of bone healing: A microarray analysis., PMID:26599085
Expression profiling of angiogenesis-related genes in brain metastases of lung cancer and melanoma., PMID:26277786
Angiopoietins promote ovarian cancer progression by establishing a procancer microenvironment., PMID:25043619
The proteinuria-hypertriglyceridemia connection as a basis for novel therapeutics for nephrotic syndrome., PMID:25005737
DNA methylation differences at growth related genes correlate with birth weight: a molecular signature linked to developmental origins of adult disease?, PMID:22498030
Current Insights into the role of HIF-1 in cutaneous wound healing., PMID:21375491
Linkage to 20p13 including the ANGPT4 gene in families with mixed Alzheimer's disease and vascular dementia., PMID:20596041
Regulation of granulosa and theca cell transcriptomes during ovarian antral follicle development., PMID:18288646
Comparative integromics on Angiopoietin family members., PMID:16685428
Assignment of ANGPT4, ANGPT1, and ANGPT2 encoding angiopoietins 4, 1 and 2 to human chromosome bands 20p13, 8q22.3-->q23 and 8p23.1, respectively, by in situ hybridization and radiation hybrid mapping., PMID:10343124
For research use only. Not for human or drug use.
