Catalog No.
AHN58001
Biological activity
Measured by its ability to inhibit proliferation of human cervical epithelial carcinoma cells (HeLa). The ED50 for this effect is 2-6 µg/mL.
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Ala31-Leu242
Nature
Recombinant
Endotoxin level
<0.1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UK85
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Dickkopf-like protein 1, Protein soggy-1, SGY-1, DKKL1, CT34, SGY1, Cancer/testis antigen 34
Associations of plasma protein levels with risk of colorectal cancer: a proteome-wide Mendelian randomization study., PMID:40462010
Whole-Genome Identification and Characterization of the DKK Gene Family and Its Transcription Profiles: An Analysis of the Chinese Soft-Shell Turtle (Pelodiscus sinensis)., PMID:38540029
Transcriptomic Analysis Reveals Intrinsic Abnormalities in Endometrial Polyps., PMID:38473810
The Multifaceted Role of Human Dickkopf-3 (DKK-3) in Development, Immune Modulation and Cancer., PMID:38201279
Comparative genomic survey and functional analysis of DKKL1 during spermatogenesis in the Chinese soft-shelled turtle (Pelodiscus sinensis)., PMID:37913874
Association of Intrauterine Microbes with Endometrial Factors in Intrauterine Adhesion Formation and after Medicine Treatment., PMID:35890029
The Clinical Significance of Dickkopf Wnt Signaling Pathway Inhibitor Gene Family in Head and Neck Squamous Cell Carcinoma., PMID:33281184
Serum biomarker analysis in patients with premature ovarian insufficiency., PMID:31629109
Hypothalamic transcriptome of tame and aggressive silver foxes (Vulpes vulpes) identifies gene expression differences shared across brain regions., PMID:31605445
A novel high-content imaging-based technique for measuring binding of Dickkopf-1 to low-density lipoprotein receptor-related protein 6., PMID:30476623
[Expression of DKKL1 in spermatozoa of men with asthenospermia]., PMID:29643039
Dickkopf homolog 3 (DKK3): A candidate for detection and treatment of cancers?, PMID:29206297
Changes in expression of Wnt signaling pathway inhibitors dickkopf-1 and sclerostin before and after total joint arthroplasty., PMID:28953627
Negative impact of high cumulative glucocorticoid dose on bone metabolism of patients with myasthenia gravis., PMID:28488158
Allele-specific splicing effects on DKKL1 and ZNF419 transcripts in HeLa cells., PMID:27826023
Expression of Cancer Testis Antigens in Colorectal Cancer: New Prognostic and Therapeutic Implications., PMID:27635108
Dickkopf-3 alters the morphological response to retinoic acid during neuronal differentiation of human embryonal carcinoma cells., PMID:24909558
Vitamin D receptor-mediated control of Soggy, Wise, and Hairless gene expression in keratinocytes., PMID:24190897
Region-specific expression of Dickkopf-like1 in the adult brain. Abbreviated title: Dkkl1 in the adult brain., PMID:23295900
Estrogen regulation of Dkk1 and Wnt/β-Catenin signaling in neurodegenerative disease., PMID:23261660
Developmental expression and function of DKKL1/Dkkl1 in humans and mice., PMID:22817830
SLXL1, a novel acrosomal protein, interacts with DKKL1 and is involved in fertilization in mice., PMID:21698294
The acrosomal protein Dickkopf-like 1 (DKKL1) facilitates sperm penetration of the zona pellucida., PMID:19596312
The acrosomal protein Dickkopf-like 1 (DKKL1) is not essential for fertility., PMID:19596310
The multi-copy mouse gene Sycp3-like Y-linked (Sly) encodes an abundant spermatid protein that interacts with a histone acetyltransferase and an acrosomal protein., PMID:19176879
Effects of FSH on testicular mRNA transcript levels in the hypogonadal mouse., PMID:19136570
Dickkopf-like1 regulates postpubertal spermatocyte apoptosis and testosterone production., PMID:18818293
Function and biological roles of the Dickkopf family of Wnt modulators., PMID:17143291
DkkL1 (Soggy), a Dickkopf family member, localizes to the acrosome during mammalian spermatogenesis., PMID:15892050
For research use only. Not for human or drug use.
