Catalog No.
AMN41301
Biological activity
Measured by its binding ability in a functional ELISA. When biotinylated recombinant rat MAG/Siglec-4a is catured on streptavidin coated plate, recombinant mouse Pirb/Lilrb3 (Cat #: AMN41301) binds with an apparent Kd < 100 nM.
Expression system
Mammalian Cells
Species
Mus musculus (Mouse)
Protein length
Gly24-Gly635
Nature
Recombinant
Endotoxin level
<0.1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8K4V6
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Paired immunoglobulin-like receptor B, Pirb, Lilrb3
Design and characterization of N-oxide cinnamanilide derivative PX5-9: Improved solubility and BDNF upregulation., PMID:40412448
Sexually dimorphic effects of angiopoietin-like 2 on energy metabolism and hypothalamic neuropeptide regulation., PMID:40133699
The LILRB family in hematologic malignancies: prognostic associations, mechanistic considerations, and therapeutic implications., PMID:39696628
Plateau hypoxia-induced upregulation of reticulon 4 pathway mediates altered autophagic flux involved in blood-brain barrier disruption after traumatic brain injury., PMID:39661527
The QS regulator AphBvp promotes expression of the AHPND PirAvp and PirBvp toxins and may enhance virulence under acidic conditions., PMID:39549792
Strain-specific differences in reovirus infection of murine macrophages segregate with polymorphisms in viral outer-capsid protein σ3., PMID:39431846
Passive immunoprophylaxis with Ccombodies against Vibrio parahaemolyticus in Pacific white shrimp (Penaeus vannamei)., PMID:39426641
PirA- or PirB-binding nanobodies can protect whiteleg shrimp from the acute hepatopancreatic necrosis disease toxin., PMID:39387475
Sialic acid and PirB are not required for targeting of neural circuits by neurotropic mammalian orthoreovirus., PMID:39320067
Genome-Wide Association Analysis Identifies LILRB2 Gene for Pathological Myopia., PMID:39207058
Comparative transcriptomic analysis of hepatopancreas reveals that more genes are involved in the exposure response of Vibrio parahaemolyticus PirAvp compared to PirBvp., PMID:39134231
Inhibition of ANGPTL8 protects against diabetes-associated cognitive dysfunction by reducing synaptic loss via the PirB signaling pathway., PMID:39095838
Effects of porcine epidemic diarrhea virus infection on CD21+ B cells activation., PMID:38663176
Proteome analysis of outer membrane vesicles from Vibrio parahaemolyticus causing acute hepatopancreatic necrosis disease., PMID:38447863
Serine protease inhibitor 3 (Serpin3) from Penaeus vannamei selectively interacts with Vibrio parahaemolyticus PirAvp., PMID:38403934
CaSSiDI: novel single-cell "Cluster Similarity Scoring and Distinction Index" reveals critical functions for PirB and context-dependent Cebpb repression., PMID:38383888
Genomic mining of Vibrio parahaemolyticus highlights prevalence of antimicrobial resistance genes and new genetic markers associated with AHPND and tdh + /trh + genotypes., PMID:38355437
Behavioral stress and antidepressant treatments altered hippocampal expression of Nogo signal-related proteins in rats., PMID:38157668
Novel sandwich immunoassay detects a shrimp AHPND-causing binary PirABVp toxin produced by Vibrio parahaemolyticus., PMID:38089817
Crystal structures of PirA and PirB toxins from Photorhabdus akhurstii subsp. akhurstii K-1., PMID:37778713
LILRB2/PirB mediates macrophage recruitment in fibrogenesis of nonalcoholic steatohepatitis., PMID:37481670
TAT-PEP Alleviated Cognitive Impairment by Alleviating Neuronal Mitochondria Damage and Apoptosis After Cerebral Ischemic Reperfusion Injury., PMID:37335462
Dual role of ANGPTL8 in promoting tumor cell proliferation and immune escape during hepatocarcinogenesis., PMID:37188659
Paired immunoglobulin-like receptor B is an entry receptor for mammalian orthoreovirus., PMID:37147336
PirB negatively regulates the inflammatory activation of astrocytes in a mouse model of sleep deprivation., PMID:37146940
A bacterial binary toxin system that kills both insects and aquatic crustaceans: Photorhabdus insect-related toxins A and B., PMID:37141203
LILRB2-containing small extracellular vesicles from glioblastoma promote tumor progression by promoting the formation and expansion of myeloid-derived suppressor cells., PMID:36853330
An opinion on the debatable function of brain resident immune protein, T-cell receptor beta subunit in the central nervous system., PMID:36590097
Transcriptome analysis of Pacific white shrimp (Liptopenaeus vannamei) after exposure to recombinant Vibrio parahaemolyticus PirA and PirB proteins., PMID:36565998
LOTUS suppresses amyloid β-induced dendritic spine elimination through the blockade of amyloid β binding to PirB., PMID:36510132
Involvement of Paired Immunoglobulin-Like Receptor B in Cognitive Dysfunction Through Hippocampal-Dependent Synaptic Plasticity Impairments in Mice Subjected to Chronic Sleep Restriction., PMID:36417104
Purification, characterization and toxicity assessment of PirAB toxins from Photorhabdus akhurstii subsp. akhurstii K-1., PMID:36167186
Myelin-associated glycoprotein alters the neuronal secretome and stimulates the release of TGFβ and proteins that affect neural plasticity., PMID:36102862
Fabrication of lateral flow immunoassay strip for rapid detection of acute hepatopancreatic necrosis disease., PMID:36033912
Murine precursors to type 1 conventional dendritic cells induce tumor cytotoxicity and exhibit activated PD-1/PD-L1 pathway., PMID:35980974
Diphenyleneiodonium Treatment Inhibits the Development of Severe Herpes Stromal Keratitis Lesions., PMID:35946937
Identification and Expression Analysis of an Interacting Protein (LvFABP) that Mediates Vibrio parahaemolyticus AHPND Toxin Action., PMID:35860240
ANGPTL8 is a negative regulator in pathological cardiac hypertrophy., PMID:35851270
Macrophage Paired Immunoglobulin-Like Receptor B Deficiency Promotes Peripheral Atherosclerosis in Apolipoprotein E-Deficient Mice., PMID:35321392
Expression of the AHPND Toxins PirAvp and PirBvp Is Regulated by Components of the Vibrio parahaemolyticus Quorum Sensing (QS) System., PMID:35270031
PT109, a novel multi-kinase inhibitor suppresses glioblastoma multiforme through cell reprogramming: Involvement of PTBP1/PKM1/2 pathway., PMID:35218719
VCAM1 confers innate immune tolerance on haematopoietic and leukaemic stem cells., PMID:35210567
Involvement of Paired Immunoglobulin-like Receptor B in Diabetes-Associated Cognitive Dysfunction Through Modulation of Axon Outgrowth and Dendritic Remodeling., PMID:35091963
Effect of remote limb ischemic post-conditioning on the expression of miR-21-5p/PirB in the brain of rats with focal cerebral ischemia., PMID:35060207
Fine definition of the epitopes on the human gp91phox/NOX2 for the monoclonal antibodies CL-5 and 48., PMID:34971634
Multifunctional carbonized nanogels to treat lethal acute hepatopancreatic necrosis disease., PMID:34952588
Acrolein, an endogenous aldehyde induces Alzheimer's disease-like pathologies in mice: A new sporadic AD animal model., PMID:34838693
Characterization of toxicity and structure of PirABvc -like proteins that are structurally almost identical to shrimp AHPND-causing PirAB toxin., PMID:34802159
Epithelial cells remove precancerous cells by cell competition via MHC class I-LILRB3 interaction., PMID:34686865
Targeting PirAvp and PirBvp Toxins of Vibrio parahaemolyticus with Oilseed Peptides: An In Silico Approach., PMID:34680792
For research use only. Not for human or drug use.
