Catalog No.
AHN01301
Biological activity
Measured by its ability to enhance anti-CD3-induced IFN-gamma secretion of mouse CD3+ T cells. The ED50 for this effect is 0.5-2.5 μg/mL.
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Gln18-Lys238
Nature
Recombinant
Endotoxin level
<0.1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
Q6UX41
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Butyrophilin-like protein 8, BTNL8
Heterozygous BTNL8 variants in individuals with multisystem inflammatory syndrome in children (MIS-C)., PMID:39576310
Conserved γδ T cell selection by BTNL proteins limits progression of human inflammatory bowel disease., PMID:37708268
Evaluation of the impacts of photodynamic therapy on the prognosis of patients with hrHPV infection based on BTNL8 expression., PMID:37456250
Autoantibody discovery across monogenic, acquired, and COVID-19-associated autoimmunity with scalable PhIP-seq., PMID:36300623
Identification of Survival-Related Genes in Acute Myeloid Leukemia (AML) Based on Cytogenetically Normal AML Samples Using Weighted Gene Coexpression Network Analysis., PMID:36212177
Autoantibody discovery across monogenic, acquired, and COVID19-associated autoimmunity with scalable PhIP-Seq., PMID:35350199
A Five-Gene Prognostic Nomogram Predicting Disease-Free Survival of Differentiated Thyroid Cancer., PMID:34221185
Identification of prognosis-related genes in the cervical cancer immune microenvironment., PMID:32946928
Ancestry and frequency of genetic variants in the general population are confounders in the characterization of germline variants linked to cancer., PMID:32375678
Butyrophilin-like 3 Directly Binds a Human Vγ4+ T Cell Receptor Using a Modality Distinct from Clonally-Restricted Antigen., PMID:31628053
Chronic Inflammation Permanently Reshapes Tissue-Resident Immunity in Celiac Disease., PMID:30739797
Novel molecules mediate specialized functions of human regulatory macrophages., PMID:30059361
New Insights Into the Regulation of γδ T Cells by BTN3A and Other BTN/BTNL in Tumor Immunity., PMID:30050536
Heteromeric interactions regulate butyrophilin (BTN) and BTN-like molecules governing γδ T cell biology., PMID:29339503
Altered expression of Butyrophilin (BTN) and BTN-like (BTNL) genes in intestinal inflammation and colon cancer., PMID:27957327
Epithelia Use Butyrophilin-like Molecules to Shape Organ-Specific γδ T Cell Compartments., PMID:27641500
Prediction of response to preoperative chemoradiotherapy and establishment of individualized therapy in advanced rectal cancer., PMID:26260776
BTNL8, a butyrophilin-like molecule that costimulates the primary immune response., PMID:24036152
A common 56-kilobase deletion in a primate-specific segmental duplication creates a novel butyrophilin-like protein., PMID:23829304
For research use only. Not for human or drug use.
