Catalog No.
AHJ05601
Biological activity
Measured by the ability of the immobilized protein to support the adhesion of human cervical epithelial carcinoma cells (HeLa). The ED50 for this effect is 0.25-1.0 μg/mL.
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Gln22-His163
Nature
Recombinant
Endotoxin level
<0.1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
Q6GTX8
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Leukocyte-associated immunoglobulin-like receptor 1, LAIR-1, hLAIR1, LAIR1, CD305
Leukemic B cells expression of CD200 and Leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1, CD305) in Chronic Lymphocytic Leukemia patients in relation to Treg frequency., PMID:39471525
Utility of leukocyte-associated immunoglobulin-like receptor-1 (CD305) in flow cytometric detection of minimal bone marrow involvement by B-cell non-Hodgkin lymphoma., PMID:39031805
Impaired LAIR-1-mediated immune control due to collagen degradation in fibrosis., PMID:38696927
Efficient delivery of the lncRNA LEF1-AS1 through the antibody LAIR-1 (CD305)-modified Zn-Adenine targets articular inflammation to enhance the treatment of rheumatoid arthritis., PMID:38062469
1,25-Dihydroxyvitamin D3 and 20-Hydroxyvitamin D3 Upregulate LAIR-1 and Attenuate Collagen Induced Arthritis., PMID:34948139
Extracellular DNA, cell surface proteins and c-di-GMP promote biofilm formation in Clostridioides difficile., PMID:33547340
Leukocyte Associated Immunoglobulin Like Receptor 1 Regulation and Function on Monocytes and Dendritic Cells During Inflammation., PMID:32973751
Immunoregulatory complement receptor-1 and leukocyte-associated Ig-like receptor-1 expression on leukocytes in Psoriasis vulgaris., PMID:32731787
Circulating Leukocyte Alterations and the Development/Progression of Diabetic Retinopathy in Type 1 Diabetic Patients - A Pilot Study., PMID:31997663
Leukocyte-associated immunoglobulin-like receptor 1 inhibits T-cell signaling by decreasing protein phosphorylation in the T-cell signaling pathway., PMID:31932281
High-Content Immunophenotyping and Hierarchical Clustering Reveal Sources of Heterogeneity and New Surface Markers of Human Blood Monocyte Subsets., PMID:31887780
Clostridium difficile clade 3 (RT023) have a modified cell surface and contain a large transposable island with novel cargo., PMID:31653906
The recent emergence of a highly related virulent Clostridium difficile clade with unique characteristics., PMID:31525517
Expression of LAIR-1 (CD305) on Human Blood Monocytes as a Marker of Hepatic Cirrhosis Progression., PMID:31019980
Low Expression of Leucocyte Associated Immunoglobulin Like Receptor-1 (LAIR-1/CD305) in a Cohort of Pediatric Acute Lymphoblastic Leukemia Cases., PMID:30486600
A non-stimulatory monoclonal antibody against the inhibitory immunoreceptor LAIR-1., PMID:24694245
Dendritic cells: In vitro culture in two- and three-dimensional collagen systems and expression of collagen receptors in tumors and atherosclerotic microenvironments., PMID:24569142
Clinical significance of LAIR1 (CD305) as assessed by flow cytometry in a prospective series of patients with chronic lymphocytic leukemia., PMID:24415628
The role of LAIR-1 (CD305) in T cells and monocytes/macrophages in patients with rheumatoid arthritis., PMID:24380839
Development and evaluation of a sandwich ELISA method for the detection of human CD306., PMID:23954474
Leukemia surfaceome analysis reveals new disease-associated features., PMID:23649467
[Mast cell inhibitory receptors]., PMID:23175328
C1q limits dendritic cell differentiation and activation by engaging LAIR-1., PMID:23093673
Inhibitory molecules that regulate expansion and restoration of HCV-specific CD4+ T cells in patients with chronic infection., PMID:21763239
CD300a is expressed on human B cells, modulates BCR-mediated signaling, and its expression is down-regulated in HIV infection., PMID:21482706
Mutual benefits of B-ALL and HLDA/HCDM HLDA 9th Barcelona 2010., PMID:20951742
Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry., PMID:20951740
Analysis of HLDA9 mAbs on plasmacytoid dendritic cells., PMID:20933012
Differential expression of SLAMS and other modulatory molecules by human plasma cells during normal maturation., PMID:20923684
Co-ordinated regulation of plasmacytoid dendritic cell surface receptors upon stimulation with herpes simplex virus type 1., PMID:19824924
A single residue, arginine 65, is critical for the functional interaction of leukocyte-associated inhibitory receptor-1 with collagens., PMID:19380792
The inhibitory collagen receptor LAIR-1 (CD305)., PMID:18063695
[Comparison of the binding affinity of LAIR-1(CD305) and LAIR-2(CD306) with their ligands]., PMID:17908491
Natalizumab therapy for moderate to severe Crohn disease in adolescents., PMID:17255829
Detection of novel leukocyte differentiation antigens on basophils and mast cells by HLDA8 antibodies., PMID:16918507
The Eighth Human Leucocyte Differentiation Antigen (HLDA8) Workshop: natural killer cell section report., PMID:16157321
[The proliferation, phenotype change and anti-tumor activity of cytokine induced killer cells]., PMID:16143062
[Identification of cell lines expressing the putative ligand(s) for LAIR-1(CD305) and LAIR-2(CD306)]., PMID:16143055
For research use only. Not for human or drug use.
