Catalog No.
AHH19001
Biological activity
Measured by its binding ability in a functional ELISA. When recombinant human EphB3 is coated at 2 μg/mL, recombinant human EFNB3 (Cat #: AHH19001) binds with an apparent Kd < 0.4 nM.
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Leu28-Ser224
Nature
Recombinant
Endotoxin level
<0.1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
Q15768
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ephrin-B3, LERK8, EPLG8, EFNB3, EPH-related receptor transmembrane ligand ELK-L3, EPH-related receptor tyrosine kinase ligand 8, LERK-8
EFNB3 Frameshift Variant in Weimaraner Dogs with a Condition Resembling a Congenital Mirror Movement Disorder., PMID:40401490
Ephrin-B1 regulates cell surface residency of heparan sulfate proteoglycans (HSPGs) and complexes with the HSPG CD44V3-10 and fibroblast growth factor receptors., PMID:40294072
Structural insights into the Langya virus attachment glycoprotein., PMID:38815575
Nipah Virus Neurotropism: Insights into Blood-Brain Barrier Disruption., PMID:38812392
Structure-guided mutagenesis of Henipavirus receptor-binding proteins reveals molecular determinants of receptor usage and antibody-binding epitopes., PMID:38426726
Ephrin B3 exacerbates colitis and colitis-associated colorectal cancer., PMID:38142837
Structure guided mutagenesis of Henipavirus Receptor Binding Proteins reveals molecular determinants of receptor usage and antibody binding epitopes., PMID:38045373
In silico prediction of interaction between Nipah virus attachment glycoprotein and host cell receptors Ephrin-B2 and Ephrin-B3 in domestic and peridomestic mammals., PMID:37924857
A Recombinant Chimeric Cedar Virus-Based Surrogate Neutralization Assay Platform for Pathogenic Henipaviruses., PMID:37243163
Integrated analysis of RNA-seq in hepatocellular carcinoma reveals competing endogenous RNA network composed of circRNA, lncRNA, and mRNA., PMID:36827016
Evaluation of the interaction between potent small molecules against the Nipah virus Glycoprotein in Malaysia and Bangladesh strains, accompanied by the human Ephrin-B2 and Ephrin-B3 receptors; a simulation approach., PMID:36808582
Prognostic Impact of Aberrantly Expressed Protein-coding Gene Associated With Gastric Cancer's Regulatory T Cells, Based on Online Databases., PMID:36735714
May EPH/Ephrin Targeting Revolutionize Lung Cancer Treatment?, PMID:36613532
Glycoprotein attachment with host cell surface receptor ephrin B2 and B3 in mediating entry of nipah and hendra virus: a computational investigation., PMID:36465097
Runs of Homozygosity Revealed Reproductive Traits of Hu Sheep., PMID:36292733
Activation of spinal ephrin-B3/EphBs signaling induces hyperalgesia through a PLP-mediated mechanism., PMID:34904278
A review on the role of different ephrins in glioma., PMID:34688637
Investigation of Key Signaling Pathways Associating miR-204 and Common Retinopathies., PMID:34646884
Cooperativity mediated by rationally selected combinations of human monoclonal antibodies targeting the henipavirus receptor binding protein., PMID:34469726
Potential genes and pathways associated with heterotopic ossification derived from analyses of gene expression profiles., PMID:34389038
Natural loss of function of ephrin-B3 shapes spinal flight circuitry in birds., PMID:34117069
Barcoded viral tracing of single-cell interactions in central nervous system inflammation., PMID:33888612
EphA4 Obstructs Spinal Cord Neuron Regeneration by Promoting Excessive Activation of Astrocytes., PMID:33595805
Transcriptomic profile of Pea3 family members reveal regulatory codes for axon outgrowth and neuronal connection specificity., PMID:33097800
A key region of molecular specificity orchestrates unique ephrin-B1 utilization by Cedar virus., PMID:31862858
High Pathogenicity of Nipah Virus from Pteropus lylei Fruit Bats, Cambodia., PMID:31855143
A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation., PMID:31745086
Structural and functional analyses reveal promiscuous and species specific use of ephrin receptors by Cedar virus., PMID:31548390
Sonic hedgehog pathway activation is associated with cetuximab resistance and EPHB3 receptor induction in colorectal cancer., PMID:31149041
Blood vessels guide Schwann cell migration in the adult demyelinated CNS through Eph/ephrin signaling., PMID:31011859
Ephrin-B3 controls excitatory synapse density through cell-cell competition for EphBs., PMID:30789343
Pituitary Transcriptomic Study Reveals the Differential Regulation of lncRNAs and mRNAs Related to Prolificacy in Different FecB Genotyping Sheep., PMID:30781725
Analysis of the association of EPHB6, EFNB1 and EFNB3 variants with hypertension risks in males with hypogonadism., PMID:30262919
Ephrin-B3 binds both cell-associated and secreted proteoglycans., PMID:29953858
The Transcription Factor LHX1 Regulates the Survival and Directed Migration of POA-derived Cortical Interneurons., PMID:29912395
Eph/ephrin signalling serves a bidirectional role in lipopolysaccharide‑induced intestinal injury., PMID:29901151
Rescue and characterization of recombinant cedar virus, a non-pathogenic Henipavirus species., PMID:29587789
Ephrin‑b3 modulates hippocampal neurogenesis and the reelin signaling pathway in a pilocarpine‑induced model of epilepsy., PMID:29512697
EphB3 signaling induces cortical endothelial cell death and disrupts the blood-brain barrier after traumatic brain injury., PMID:29311672
Idiosyncratic Mòjiāng virus attachment glycoprotein directs a host-cell entry pathway distinct from genetically related henipaviruses., PMID:28699636
Eph/Ephrin Signaling Controls Progenitor Identities In The Ventral Spinal Cord., PMID:28595615
Identification and characterization of Nanobodies targeting the EphA4 receptor., PMID:28526745
Ephrin-B3 supports glioblastoma growth by inhibiting apoptosis induced by the dependence receptor EphA4., PMID:28423606
Evidence from single nucleotide polymorphism analyses of ADVANCE study demonstrates EFNB3 as a hypertension risk gene., PMID:28272517
The role of GRIP1 and ephrin B3 in blood pressure control and vascular smooth muscle cell contractility., PMID:27941904
Ephrin Bs and canonical Reelin signalling., PMID:27882975
EphrinB1/EphB3b Coordinate Bidirectional Epithelial-Mesenchymal Interactions Controlling Liver Morphogenesis and Laterality., PMID:27825440
EphrinB3 restricts endogenous neural stem cell migration after traumatic brain injury., PMID:27771498
Amygdala EphB2 Signaling Regulates Glutamatergic Neuron Maturation and Innate Fear., PMID:27683910
Ephrin B3 interacts with multiple EphA receptors and drives migration and invasion in non-small cell lung cancer., PMID:27533087
For research use only. Not for human or drug use.
