Catalog No.
AHG92701
Biological activity
Measured by its ability to bind HLA on human breast cancer cells (MDA‑MB‑231). The ED50 for this effect is 0.03-0.18 μg/mL.
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
His22-His340
Nature
Recombinant
Endotoxin level
<0.1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
Q14943
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Killer cell immunoglobulin-like receptor 3DS1, MHC class I NK cell receptor, NKAT-10, NKAT10, KIR3DS1, Natural killer-associated transcript 10
The Impact of Killer Cell Immunoglobulin-Like Receptors and Human Leukocyte Antigen-E, Human Leukocyte Antigen-G Polymorphisms on Innate Immunity and COVID-19 Severity., PMID:40391199
Association of killer cell immunoglobulin-like receptor genes with primary Sjögren's syndrome among Chinese population., PMID:39947039
Identification of four novel KIR alleles in haematopoietic stem cell donors of Indian origin., PMID:39162080
Killer-cell immunoglobulin-like receptor polymorphism is associated with COVID-19 outcome: Results of a pilot observational study., PMID:39148254
Activating KIR/HLA-I combinations as a risk factor of adult B-ALL., PMID:38262874
High-resolution characterization of KIR genes polymorphism in healthy subjects from the Bulgarian population-A pilot study., PMID:38180282
Donor aKIR genes influence the risk of EBV and CMV reactivation after anti-thymocyte globulin-based haploidentical hematopoietic stem cell transplantation., PMID:38081622
HLA-F and LILRB1 Genetic Polymorphisms Associated with Alloimmunisation in Sickle Cell Disease., PMID:37686397
Evaluation of KIR3DL1/KIR3DS1 allelic polymorphisms in Kenyan children with endemic Burkitt lymphoma., PMID:37647275
Association of killer cell immunoglobulin-like receptors and their cognate HLA class I ligands with susceptibility to acute myeloid leukemia in Iranian patients., PMID:37454198
Killer cell immunoglobulin-like receptor (KIR) genes and their HLA ligands in a Brazilian population., PMID:37350049
Expression profile of KIR3DS1/KIR3DL1 receptors in association with immunological responses in TB, HIV and HIV/TB infected patients., PMID:37169313
HLA-F transcriptional and protein differential expression according to its genetic polymorphisms., PMID:37166140
KIR genotype and haplotype repertoire in Kuwaiti healthy donors, hematopoietic cell transplant recipients and healthy family members., PMID:36960942
Co-Expression Analysis of Airway Epithelial Transcriptome in Asthma Patients with Eosinophilic vs. Non-Eosinophilic Airway Infiltration., PMID:36835202
Killer cell immunoglobulin-like receptor three domains long cytoplasmic tail 1 gene *007 may modulate disease progression of human immunodeficiency virus-1 infection in the Japanese population., PMID:36807537
The impact of killer cell immunoglobulin-like receptor (KIR) genes and human leukocyte antigen (HLA) class I ligands on predisposition or protection against prostate cancer., PMID:36599262
Understanding the killer-cell immunoglobulin like receptor polymorphism in retinoblastoma., PMID:36594723
KIR-HLA gene diversities and susceptibility to lung cancer., PMID:36241658
Killer-Cell Immunoglobulin-like Receptor Diversity in an Admixed South American Population., PMID:36139351
Mobilisation of HLA-F on the surface of bronchial epithelial cells and platelets in asthmatic patients., PMID:35988034
Allele imputation for the killer cell immunoglobulin-like receptor KIR3DL1/S1., PMID:35192601
Evaluation of telomeric KIR genes and their association with CMV infection in kidney transplant recipients., PMID:35091752
A Genome-Wide CRISPR/Cas9-Based Screen Identifies Heparan Sulfate Proteoglycans as Ligands of Killer-Cell Immunoglobulin-Like Receptors., PMID:34917099
Donor activating killer cell immunoglobulin-like receptors genes correlated with Epstein-Barr virus reactivation after haploidentical haematopoietic stem cell transplantation., PMID:34787307
KIR3DS1 directs NK cell-mediated protection against human adenovirus infections., PMID:34533978
Large-Scale Imputation of KIR Copy Number and HLA Alleles in North American and European Psoriasis Case-Control Cohorts Reveals Association of Inhibitory KIR2DL2 With Psoriasis., PMID:34177931
Dynamic mRNA expression of donor-derived activating KIR genes and their significant effects on clinical outcome after haematopoietic stem cell transplantation., PMID:34085290
Activating Killer-Cell Immunoglobulin-Like Receptors Are Associated With the Severity of Coronavirus Disease 2019., PMID:33928374
Natural killer cells play an important role in virus infection control: Antiviral mechanism, subset expansion and clinical application., PMID:33887436
Diversity of KIR genes and their HLA-C ligands in Ugandan populations with historically varied malaria transmission intensity., PMID:33632228
Upregulation of HLA-F expression by BK polyomavirus infection induces immune recognition by KIR3DS1-positive natural killer cells., PMID:33359499
The Loss of HLA-F/KIR3DS1 Ligation Is Mediated by Hemoglobin Peptides., PMID:33126487
Association of killer-cell immunoglobulin-like receptor genes with acute myelogenous leukaemia., PMID:32767509
Resistance of KIR Ligand-Missing Leukocytes to NK Cells In Vivo in Patients with Acquired Aplastic Anemia., PMID:32680908
The effect of KIR and HLA polymorphisms on dengue infection and disease severity in northeastern Thais., PMID:32524212
Diversity of KIR/HLA Genotypes and Their Association with Psoriasis Vulgaris in the Western Mexican Population., PMID:32235781
Killer Cell Immunoglobulin-Like Receptor Genotypes and Haplotypes Contribute to Susceptibility to Hepatitis B Virus and Hepatitis C Virus Infection in Cameroon., PMID:31977279
Study of KIR gene expression at the mRNA level in specific donor-derived NK cells after allogeneic HSCT., PMID:31900503
Role of Killer cell immunoglobulin-like receptors (KIR) genes in stages of HIV-1 infection among patients from Burkina Faso., PMID:31863692
Activating killer cell immunoglobulin-like receptors: Detection, function and therapeutic use., PMID:31755661
HLA-F Allele-Specific Peptide Restriction Represents an Exceptional Proteomic Footprint., PMID:31717259
KIR3DL1/S1 Allotypes Contribute Differentially to the Development of Behçet Disease., PMID:31405953
Certain Killer Immunoglobulin-Like Receptor (KIR)/KIR HLA Class I Ligand Genotypes Influence Natural Killer Antitumor Activity in Myelogenous Leukemia but Not in Acute Lymphoblastic Leukemia: A Case Control Leukemia Association Study., PMID:31337191
The Role of Killer Immunoglobulin-Like Receptor Genes in Susceptibility to HIV-1 Infection and Disease Progression: A Meta-Analysis., PMID:31288555
HLA-F on Autologous HIV-Infected Cells Activates Primary NK Cells Expressing the Activating Killer Immunoglobulin-Like Receptor KIR3DS1., PMID:31270222
Activating KIRs on Educated NK Cells Support Downregulation of CD226 and Inefficient Tumor Immunosurveillance., PMID:31239317
Decreased interferon-γ production by NK cells from KIR haplotype B carriers in hepatitis C virus infection., PMID:31177636
Fluctuating and Geographically Specific Selection Characterize Rapid Evolution of the Human KIR Region., PMID:31156615
The Emerging Roles of Human Leukocyte Antigen-F in Immune Modulation and Viral Infection., PMID:31134067
For research use only. Not for human or drug use.
