Catalog No.
AHF95301
Biological activity
Measured by its ability to transfer GlcNAc from UDPGlcNAc to B1-3 galactosyl-Nacetyl galactosamine. The specific activity is >350 pmol/min/μg, as measured under the described conditions.
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Arg33-His428
Nature
Recombinant
Endotoxin level
<0.1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
Q02742
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Core 2 GNT, GCNT1, Core2-GlcNAc-transferase, Core 2-branching enzyme, NACGT2, Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase, C2GNT
Lamb Performance and Meat Quality: The Impact of Chromium in High-Concentrate Diets and Its Molecular Effects on Skeletal Muscle During Finishing Phase., PMID:40011411
The glycoimmune checkpoint receptor Siglec-7 interacts with T-cell ligands and regulates T-cell activation., PMID:38141764
Transcriptome-wide association study of circulating IgE levels identifies novel targets for asthma and allergic diseases., PMID:36793728
Genome-wide placental DNA methylations in fetal overgrowth and associations with leptin, adiponectin and fetal growth factors., PMID:36585686
Molecular Basis and Role of Siglec-7 Ligand Expression on Chronic Lymphocytic Leukemia B Cells., PMID:35711441
Installation of O-glycan sulfation capacities in human HEK293 cells for display of sulfated mucins., PMID:34954141
Exploring Prognosis-Associated Biomarkers of Estrogen-Independent Uterine Corpus Endometrial Carcinoma by Bioinformatics Analysis., PMID:34876842
Uncovering the anti-angiogenic effect of semisynthetic triterpenoid CDDO-Im on HUVECs by an integrated network pharmacology approach., PMID:34802714
Sulfation of O-glycans on Mucin-type Proteins From Serous Ovarian Epithelial Tumors., PMID:34555499
Genome-wide association study of high-sensitivity C-reactive protein, D-dimer, and interleukin-6 levels in multiethnic HIV+ cohorts., PMID:33095540
Parallel Glyco-SPOT Synthesis of Glycopeptide Libraries., PMID:32610041
GCNT1-Mediated O-Glycosylation of the Sialomucin CD43 Is a Sensitive Indicator of Notch Signaling in Activated T Cells., PMID:32060138
Single-Cell Analysis Reveals Heterogeneity of High Endothelial Venules and Different Regulation of Genes Controlling Lymphocyte Entry to Lymph Nodes., PMID:30865898
Human B Cell Differentiation Is Characterized by Progressive Remodeling of O-Linked Glycans., PMID:30619255
[Development and Clinical Application of Glycan-Targeted Biomarkers for Prostate Cancer]., PMID:30762989
Functions of Smad Transcription Factors in TGF-β1-Induced Selectin Ligand Expression on Murine CD4 Th Cells., PMID:27543612
Core 2 ß1,6-N-acetylglucosaminyltransferase-I, crucial for P-selectin ligand expression is controlled by a distal enhancer regulated by STAT4 and T-bet in CD4+ T helper cells 1., PMID:27505708
The androgen receptor controls expression of the cancer-associated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer., PMID:26452038
A Panel of Recombinant Mucins Carrying a Repertoire of Sialylated O-Glycans Based on Different Core Chains for Studies of Glycan Binding Proteins., PMID:26274979
Diverse inflammatory cytokines induce selectin ligand expression on murine CD4 T cells via p38α MAPK., PMID:25941329
Restoration of compact Golgi morphology in advanced prostate cancer enhances susceptibility to galectin-1-induced apoptosis by modifying mucin O-glycan synthesis., PMID:25086069
Increased expression of GCNT1 is associated with altered O-glycosylation of PSA, PAP, and MUC1 in human prostate cancers., PMID:24854630
Determination of carbohydrate structure recognized by prostate-specific F77 monoclonal antibody through expression analysis of glycosyltransferase genes., PMID:24753248
IL-15 regulates memory CD8+ T cell O-glycan synthesis and affects trafficking., PMID:24509081
[Research on differentially expressed genes related to substance and energy metabolism between healthy volunteers and splenasthenic syndrome patients with chronic superficial gastritis]., PMID:23646466
Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity., PMID:22454501
For research use only. Not for human or drug use.
