Catalog No.
AHF79701
Biological activity
When recombinant Mouse EphB3 is coated at 2 μg/mL, recombinant human EFNB1 (Cat #: AHF79701) binds with an apparent KD <0.2 nM.
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Leu28-Gly232
Nature
Recombinant
Endotoxin level
<0.1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
P98172
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ephrin-B1, EFNB1, LERK2, LERK-2, EPLG2, ELK ligand, Ephrin-B1 ICD, ELK-L, EFL3, EFL-3, Ephrin-B1 CTF, EPH-related receptor tyrosine kinase ligand 2
Cdc42 Activation in Anti-nephrin Antibody-Induced Nephropathy., PMID:40459930
Ephrin-B1 regulates cell surface residency of heparan sulfate proteoglycans (HSPGs) and complexes with the HSPG CD44V3-10 and fibroblast growth factor receptors., PMID:40294072
Proteomic insights into metabolic dysfunction-associated steatotic disease: Identifying therapeutic targets and assessing on-target side effects., PMID:40287056
Ephrin B1 and B2 Mediate Cedar Virus Entry into Egyptian Fruit Bat Cells., PMID:40285015
EphB2-mediated ephrin-B reverse signaling on microglia drives an anti-viral, but inflammatory and neurotoxic response associated with HIV., PMID:40235485
Metabolic expression profiling analysis reveals pyruvate-mediated EPHB2 upregulation promotes lymphatic metastasis in head and neck squamous cell carcinomas., PMID:40075431
EFNB1 drives glioma progression and shapes the immune microenvironment: a potential prognostic biomarker., PMID:40014231
Melatonin enhances neurogenesis and neuroplasticity in long-term recovery following cerebral ischemia in mice., PMID:39993544
N-glycosylation of ephrin B1 modulates its function and confers therapeutic potential in B-cell lymphoma., PMID:39864628
Research progress on the molecular structure, function, and application in tumor therapy of zinc transporter ZIP4., PMID:39664563
Reciprocal tumor-platelet interaction through the EPHB1-EFNB1 axis in the liver metastatic niche promotes metastatic tumor outgrowth in pancreatic ductal adenocarcinoma., PMID:39648610
Craniofrontonasal syndrome in a patient with an inv(X)(p22.2q13.1), separating EFNB1 from its enhancer., PMID:39643662
EphA4 Mediates EphrinB1-Dependent Adhesion in Retinal Ganglion Cells., PMID:39622649
EphB4 and ephrin-B1 expression in the intra-testicular-resident macrophages in mice., PMID:39605768
Time-Lapse Acquisition of Both Freely Secreted Proteome and Exosome Encapsulated Proteome in Live Organoids' Microenvironment., PMID:39573935
Exploring the ceRNA network involving AGAP2-AS1 as a novel biomarker for preeclampsia., PMID:39521940
Astrocytic Ephrin-B1 Regulates Oligodendrocyte Development and Myelination., PMID:39437409
EphB2, EphB4, and ephrin-B1 expression and localization in postnatal developing epididymis in mice., PMID:39390685
EphB2 Signaling Is Implicated in Astrocyte-Mediated Parvalbumin Inhibitory Synapse Development., PMID:39327008
Case Report: Whole exome sequencing identifies compound heterozygous variants in the TRAPPC9 gene in a child with developmental delay., PMID:39184350
Excitatory to inhibitory synaptic ratios are unchanged at presymptomatic stages in multiple models of ALS., PMID:39088455
Predictive biomarkers for response to TGF- β inhibition in resensitizing chemo(radiated) esophageal adenocarcinoma., PMID:39059615
Structural insights into the Langya virus attachment glycoprotein., PMID:38815575
EphB1 causes retinal damage through inflammatory pathways in the retina and retinal Müller cells., PMID:38601015
Ephrin B1 Regulates Inflammatory Pathways in Retinal Müller Cells., PMID:38501146
Engineered cocultures of iPSC-derived atrial cardiomyocytes and atrial fibroblasts for modeling atrial fibrillation., PMID:38241367
EFNB1 levels determine distinct drug response patterns guiding precision therapy for B-cell neoplasms., PMID:38155773
Interaction between the EPHB2 receptor and EFNB1 ligand drives gastric cancer invasion and metastasis via the Wnt/β-catenin/FAK pathway., PMID:38114003
Aberrant epithelial cell interaction promotes esophageal squamous-cell carcinoma development and progression., PMID:38097539
Colorectal cancer-associated mutations impair EphB1 kinase function., PMID:37527777
High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface., PMID:37499664
Ephrin B/EphB in neuropathic pain: Role and molecular mechanisms., PMID:37401197
Differentially Expressed Genes Induced by Erythropoietin Receptor Overexpression in Rat Mammary Adenocarcinoma RAMA 37-28 Cells., PMID:37239828
[Clinical and genetic analysis of a patient with Craniofrontonasal syndrome]., PMID:37212007
Identification of Myelin Basic Protein Proximity Interactome Using TurboID Labeling Proteomics., PMID:36980286
Ephrin-B1 regulates the adult diastolic function through a late postnatal maturation of cardiomyocyte surface crests., PMID:36649053
Kindlin2 enables EphB/ephrinB bi-directional signaling to support vascular development., PMID:36574991
Heterogeneity in the size of the apical surface of cortical progenitors., PMID:36153792
The Functions of EphA1 Receptor Tyrosine Kinase in Several Tumors., PMID:35996244
Identification of fusions with potential clinical significance in melanoma., PMID:35871080
Metalloprotease ADAM9 cleaves ephrin-B ligands and differentially regulates Wnt and mTOR signaling downstream of Akt kinase in colorectal cancer cells., PMID:35780836
Eph and Ephrin Variants in Malaysian Neural Tube Defect Families., PMID:35741713
Construction of three-gene-based prognostic signature and analysis of immune cells infiltration in children and young adults with B-acute lymphoblastic leukemia., PMID:35603962
The Unconventional Growth Factors Cerebral Dopamine Neurotrophic Factor and Mesencephalic Astrocyte-Derived Neurotrophic Factor Promote Post-ischemic Neurological Recovery, Perilesional Brain Remodeling, and Lesion-Remote Axonal Plasticity., PMID:35583716
Time-series expression profiles of mRNAs and lncRNAs during mammalian palatogenesis., PMID:35506257
mRNA expression analysis of the hippocampus in a vervet monkey model of fetal alcohol spectrum disorder., PMID:35305552
Craniomaxillofacial morphology in a murine model of ephrinB1 conditional deletion in osteoprogenitor cells., PMID:35299000
Investigating the effects of compound paralogous EPHB receptor mutations on mouse facial development., PMID:35025117
β-Tubulin Isotype, TUBB4B, Regulates The Maintenance of Cancer Stem Cells., PMID:35004310
EFNB1 Acts as a Novel Prognosis Marker in Glioblastoma through Bioinformatics Methods and Experimental Validation., PMID:34824583
For research use only. Not for human or drug use.
