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Recombinant Mouse LUM/Lumican Protein, C-His (Active)

Catalog #:   AME89701 Specific References (50) DATASHEET
Applications: Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Expression system: Mammalian Cells
Accession: P51885
Protein length: Gln19-Asn338
Overview

Catalog No.

AME89701

Biological activity

Measured by the ability of the immobilized protein to support the adhesion of bovine corneal endothelial cells (BCE C/D‑1b). When 5 x 10^4 cells per well are added to rmLUM/Lumican (Cat #: AME89701) coated plates (10 μg/mL, 100 μL/well) ≥ 50% will adhere after 50 minutes at 37 ℃.

Expression system

Mammalian Cells

Species

Mus musculus (Mouse)

Protein length

Gln19-Asn338

Nature

Recombinant

Endotoxin level

<0.1 EU/μg of the protein by the LAL method.

Purity

>90% as determined by SDS-PAGE.

Accession

P51885

Applications

Bioactivity, ELISA, Immunogen, SDS-PAGE, WB

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

Keratan sulfate proteoglycan lumican, Lumican, SLRR2D, LDC, LUM, KSPG lumican

Data Image
References

Murine maternal microbiome modifies adverse effects of protein undernutrition on offspring neurobehaviour., PMID:40514563

Single Cell Spatial Profiling Identifies Region-Specific Extracellular Matrix Adhesion and Signaling Networks in Glioblastoma., PMID:40496929

TIM3 and TIGIT-expressing CD4 T cells are impacted by kidney transplantation and associated with risk of infection., PMID:40475763

Multi-Reflectance-Spectroscopy, Part II: Optical Sensor for In-Line Monitoring of Fat and Protein in Milk-Based Products., PMID:40462594

Normal hearing function genetics: have you heard all about it? An integrated approach of genome-wide association studies and transcriptome-wide association studies in three Italian cohorts., PMID:40458558

Risk factors for mortality and implications on therapy for Stenotrophomonas maltophilia bacteraemia., PMID:40409223

Isocitrate dehydrogenase 1 primes group-3 medulloblastomas for cuproptosis., PMID:40378837

PLASMIC score to aid diagnosis of aHUS: an analysis of C5 inhibitor clinical trials and the PINC AI™ healthcare database., PMID:40375186

Cystathionine gamma-lyase-mediated hypoxia inducible factor 1-alpha expression drives clear cell ovarian cancer progression., PMID:40371821

Transcriptomic analysis after SARS-CoV-2 mRNA vaccination reveals a specific gene signature in low-responder hemodialysis patients., PMID:40370459

Intra-amniotic antisense oligonucleotide treatment improves phenotypes in preclinical models of spinal muscular atrophy., PMID:40367190

Iron Metabolism and Muscle Aging: Where Ferritinophagy Meets Mitochondrial Quality Control., PMID:40358196

Proteomic signatures of retinal pigment epithelium-derived exosomes in myopic and non-myopic tree shrew eyes., PMID:40330779

Cohort profile: the Swedish Inception Cohort in inflammatory bowel disease (SIC-IBD)., PMID:40328654

Corrigendum to "Altered mitochondrial unfolded protein response and protein quality control promote oxidative distress in down syndrome brain" [Free Radic. Biol. Med. 227 (2025) 80-93]., PMID:40328573

One-Pot Synthesis of Antibacterial and Antioxidant Self-Healing Bioadhesives Using Ugi Four-Component Reactions., PMID:40317897

Investigation of the Pathogenesis of Liver Fibrosis Associated with Type 2 Diabetes Mellitus via Bioinformatic Analysis., PMID:40299397

Novel microfluidic device for factor VIII quantification by chemiluminescence in hemophilia A patients., PMID:40286644

Tumoroid Model Reveals Synergistic Impairment of Metabolism by Iron Chelators and Temozolomide in Chemo-Resistant Patient-derived Glioblastoma Cells., PMID:40285641

Inflammatory phenotypes and clinical outcomes amongst patients with presumed and confirmed Pneumocystis jirovecii pneumonia without underlying human immunodeficiency virus infection., PMID:40275495

Longitudinal changes in blood-borne geroscience biomarkers: results from a population-based study., PMID:40272732

In-Gel Zymography of Amyotrophic Lateral Sclerosis-Associated Variants of Superoxide Dismutase-1., PMID:40261626

Anti-integrin αvβ6 IgG antibody as a diagnostic and prognostic marker in ulcerative colitis: A cross-sectional and longitudinal study defining a specific disease phenotype., PMID:40251889

A polytherapy approach demonstrates therapeutic efficacy for the treatment of SOD1 associated amyotrophic lateral sclerosis., PMID:40222103

Spatial determinants of antibody-drug conjugate SHR-A1811 efficacy in neoadjuvant treatment for HER2-positive breast cancer., PMID:40215979

Vorinostat impairs the cancer-driving potential of leukemia-secreted extracellular vesicles., PMID:40211278

Conjugation to a transferrin receptor 1-binding Bicycle peptide enhances ASO and siRNA potency in skeletal and cardiac muscles., PMID:40207629

Lumican as a potential biomarker for diabetic nephropathy., PMID:40195568

SARS-CoV2 variants differentially impact on the plasma metabolome., PMID:40186806

Unravelling the impact of the chromobox proteins in human cancers., PMID:40175347

Tumor cell heterogeneity drives spatial organization of the intratumoral immune response., PMID:40167599

MCL‑1 safeguards activated hair follicle stem cells to enable adult hair regeneration., PMID:40121237

A Randomized Trial of Automated Insulin Delivery in Type 2 Diabetes., PMID:40105270

Comparative Efficacy of CFTR Modulators: A Network Meta-analysis., PMID:40102290

Knockdown of TGFB2 Attenuates Ischemic Heart Failure by Inhibiting Apoptosis., PMID:40080329

Zinc Ion Dyshomeostasis in Autism Spectrum Disorder., PMID:40079191

A rapid ecologic analysis, confirmed by a case-control study, identifies class I HLA alleles correlated to the risk of COVID-19., PMID:40065352

Compositional changes of the lung extracellular matrix in acute respiratory distress syndrome., PMID:40063067

Age- and sex-dependency of thrombin generation parameters in the general Italian population: the Moli-sani study., PMID:40060967

Inactivation of NLRP3 inflammasome by dephosphorylation at Serine 658 alleviates glial inflammation in the mouse model of Parkinson's disease., PMID:40038816

The relationship between serum Lumican levels and myocardial fibrosis in patients with hypertrophic cardiomyopathy., PMID:40033847

Osteopontin in rheumatic diseases: A systematic review and meta-analysis., PMID:39988302

Epidemiology of bluetongue virus infection among goat populations in central and western Thailand: Prevalence, risk factors, and serotype analysis., PMID:39970832

Roles of WDR12 and MRTO4 genes in colorectal cancer., PMID:39969382

Transition to retirement impact on food consumption frequency: results from a longitudinal analysis within the Survey of Health, Ageing and Retirement in Europe (SHARE)., PMID:39952014

From Cell Architecture to Mitochondrial Signaling: Role of Intermediate Filaments in Health, Aging, and Disease., PMID:39940869

Dynamics of molecular heterogeneity in high-risk luminal breast cancer-From intrinsic to adaptive subtyping., PMID:39933898

Proteomic profiling reveals biological processes and biomarkers involved in the pathogenesis of occult breast cancer., PMID:39930421

Integration of single-cell and bulk RNA sequencing data using machine learning identifies oxidative stress-related genes LUM and PCOLCE2 as potential biomarkers for heart failure., PMID:39929468

Single-cell atlas of human pancreatic islet and acinar endothelial cells in health and diabetes., PMID:39915484

Datasheet
$ 360
Product specifications
50 μg 360 100 μg 580

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For research use only. Not for human or drug use.

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Recombinant Mouse LUM/Lumican Protein, C-His (Active) [AME89701]
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