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Recombinant Human CTSE Protein, C-10*His (Active)

Catalog #:   AHD03001 Specific References (50) DATASHEET
Applications: Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Expression system: Mammalian Cells
Accession: P14091
Protein length: Gln18-Pro396
Overview

Catalog No.

AHD03001

Biological activity

Measured by its ability to cleave the fluorogenic peptide substrate, Mca-PLGL-DpaAR-NH2. The specific activity is >1,500 pmol/min/µg, as measured under the described conditions.

Expression system

Mammalian Cells

Species

Homo sapiens (Human)

Protein length

Gln18-Pro396

Nature

Recombinant

Endotoxin level

<0.1 EU/μg of the protein by the LAL method.

Purity

>90% as determined by SDS-PAGE.

Accession

P14091

Applications

Bioactivity, ELISA, Immunogen, SDS-PAGE, WB

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

CTSE, Cathepsin E

Data Image
References

CTSE inhibits anti-tumor T cell response by promoting des-γ-carboxy prothrombin releasing in hepatocellular carcinoma., PMID:40467555

Menin maintains lysosomal and mitochondrial homeostasis through epigenetic mechanisms in lung cancer., PMID:40057469

Assessing the Causal Relationship Between Plasma Proteins and Pulmonary Fibrosis: A Systematic Analysis Based on Mendelian Randomization., PMID:40001968

Integrative multi-omics and machine learning identify a robust signature for discriminating prognosis and therapeutic targets in bladder cancer., PMID:39991573

Shaoyao decoction alleviates DSS-induced colitis by inhibiting IL-17a-mediated polarization of M1 macrophages., PMID:39427735

Machine learning identifies SLC6A14 as a novel biomarker promoting the proliferation and metastasis of pancreatic cancer via Wnt/β-catenin signaling., PMID:38267509

Novel insights into the nervous system affected by prolonged hyperglycemia., PMID:37462767

FVB/N mouse strain regulatory T cells differ in phenotype and function from the C57BL/6 and BALB/C strains., PMID:36238362

Proteomic characterization of gastric cancer response to chemotherapy and targeted therapy reveals new therapeutic strategies., PMID:36175412

Microglial cathepsin E plays a role in neuroinflammation and amyloid β production in Alzheimer's disease., PMID:35181976

Construction of miRNA-mRNA-TF Regulatory Network for Diagnosis of Gastric Cancer., PMID:34840985

Dynamic Urinary Proteome Changes in Ovalbumin-Induced Asthma Mouse Model Using Data-Independent Acquisition Proteomics., PMID:34785909

Aging whole blood transcriptome reveals candidate genes for SARS-CoV-2-related vascular and immune alterations., PMID:34741638

Natural Compounds from Hatikana Extract Potentiate Antidiabetic Actions as Displayed by In Vivo Assays and Verified by Network Pharmacological Tools., PMID:34725640

Gene Expression Profiles Associated with Radio-Responsiveness in Locally Advanced Rectal Cancer., PMID:34205090

TSPAN1, TMPRSS4, SDR16C5, and CTSE as Novel Panel for Pancreatic Cancer: A Bioinformatics Analysis and Experiments Validation., PMID:33815409

A TP53-Associated Immune Prognostic Signature for the Prediction of Overall Survival and Therapeutic Responses in Muscle-Invasive Bladder Cancer., PMID:33391264

Identification and validation of an immune-related gene-based prognostic index for bladder cancer., PMID:33042413

Pathogenic infection and immune-related gene expression of Chinese sturgeon (Acipenser sinensis) challenged by Citrobacter freundii., PMID:32949686

Integrated Analyses Identify Immune-Related Signature Associated with Qingyihuaji Formula for Treatment of Pancreatic Ductal Adenocarcinoma Using Network Pharmacology and Weighted Gene Co-Expression Network., PMID:32537471

Grassystatin-derived peptides selectively inhibit cathepsin E and have low affinity to cathepsin D., PMID:32446374

First report of cathepsin E in a teleost (Korean rose bitterling, Rhodeus uyekii): Molecular characterisation and tissue distribution., PMID:31904433

Single-cell transcriptomics reveals the landscape of intra-tumoral heterogeneity and stemness-related subpopulations in liver cancer., PMID:31195060

Cathepsin E in neutrophils contributes to the generation of neuropathic pain in experimental autoimmune encephalomyelitis., PMID:31095099

Regulation of Cathepsin E gene expression by the transcription factor Kaiso in MRL/lpr mice derived CD4+ T cells., PMID:30816218

Exploring and comparing of the gene expression and methylation differences between lung adenocarcinoma and squamous cell carcinoma., PMID:30317601

The Relationship between the Concentration of Cathepsin A, D, and E and the Concentration of Copper and Zinc, and the Size of the Aneurysmal Enlargement in the Wall of the Abdominal Aortic Aneurysm., PMID:30278264

Naturally-occurring canine invasive urothelial carcinoma harbors luminal and basal transcriptional subtypes found in human muscle invasive bladder cancer., PMID:30089113

PPARα-Target Gene Expression Requires TIS21/BTG2 Gene in Liver of the C57BL/6 Mice under Fasting Condition., PMID:29385670

Combination of active targeting, enzyme-triggered release and fluorescent dye into gold nanoclusters for endomicroscopy-guided photothermal/photodynamic therapy to pancreatic ductal adenocarcinoma., PMID:28582716

rHuKGF ameliorates protease/anti-protease imbalance in emphysematous mice., PMID:28552795

Cathepsin E Deficiency Ameliorates Graft-versus-Host Disease and Modifies Dendritic Cell Motility., PMID:28298913

Environmental enrichment attenuates the blood brain barrier dysfunction induced by the neonatal hypoxia-ischemia., PMID:27326908

Protective effects of a Chotosan Fraction and its active components on β-amyloid-induced neurotoxicity., PMID:26876445

Autophagic digestion of Leishmania major by host macrophages is associated with differential expression of BNIP3, CTSE, and the miRNAs miR-101c, miR-129, and miR-210., PMID:26226952

Unstable Foxp3+ regulatory T cells and altered dendritic cells are associated with lipopolysaccharide-induced fetal loss in pregnant interleukin 10-deficient mice., PMID:26224007

Gastric-type expression signature in serrated pathway-associated colorectal tumors., PMID:25704805

Environmental stimulation improves performance in the ox-maze task and recovers Na+,K+-ATPase activity in the hippocampus of hypoxic-ischemic rats., PMID:25617656

Characterization and localization of the Campylobacter jejuni transformation system proteins CtsE, CtsP, and CtsX., PMID:25448813

High Expression of Cathepsin E in Tissues but Not Blood of Patients with Barrett's Esophagus and Adenocarcinoma., PMID:25348778

Cathepsin E promotes pulmonary emphysema via mitochondrial fission., PMID:25239563

A novel genomic signature with translational significance for human idiopathic pulmonary fibrosis., PMID:25029475

Defective adipose tissue development associated with hepatomegaly in cathepsin E-deficient mice fed a high-fat diet., PMID:24583126

Role of cathepsin E in decidual macrophage of patients with recurrent miscarriage., PMID:24464956

Lysosomal alkalization and dysfunction in human fibroblasts with the Alzheimer's disease-linked presenilin 1 A246E mutation can be reversed with cAMP., PMID:24418614

Cathepsin E deficiency impairs autophagic proteolysis in macrophages., PMID:24340026

Allergic airway inflammation in mice deficient for the antigen-processing protease cathepsin E., PMID:22846634

[Screen and validation of differentially expressing genes related to silicotic pulmonary fibrosis in rats]., PMID:22730688

Decreased expression of MHC class II and cathepsin E in dendritic cells might contribute to impaired induction of antigen-specific T cell response in NC/Nga mice., PMID:22449997

Cathepsin E, maspin, Plk1, and survivin are promising prognostic protein markers for progression in non-muscle invasive bladder cancer., PMID:22449953

Datasheet
$ 360
Product specifications
50 μg 360 100 μg 580

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For research use only. Not for human or drug use.

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Recombinant Human CTSE Protein, C-10*His (Active) [AHD03001]
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