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Recombinant Human GHR Protein, C-hFc-His (Active)

Catalog #:   AHC84301 Specific References (50) DATASHEET
Applications: Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Expression system: Mammalian Cells
Accession: P10912
Protein length: Ala27-Tyr264
Overview

Catalog No.

AHC84301

Biological activity

Immobilized human GH at 2 μg/mL (100 μL/well) can bind human GHR (CAT #: AHC84301) with a linear range of 0.1-8.58 ng/mL.

Expression system

Mammalian Cells

Species

Homo sapiens (Human)

Protein length

Ala27-Tyr264

Nature

Recombinant

Endotoxin level

<0.1 EU/μg of the protein by the LAL method.

Purity

>90% as determined by SDS-PAGE.

Accession

P10912

Applications

Bioactivity, ELISA, Immunogen, SDS-PAGE, WB

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

GHR, GH-binding protein, Growth hormone receptor, GHBP, Somatotropin receptor, GH receptor, Serum-binding protein

Data Image
  • SDS-PAGE
    SDS-PAGE for Recombinant Human Growth hormone receptor protein
  • Bioactivity
    Immobilized human GH at 2 μg/mL (100 μL/well) can bind human GHR (CAT #: AHC84301) with a linear range of 0.1-8.58 ng/mL.
References

Influence of ethnicity on the diagnostic accuracy of plasma p-tau217 for the identification of Alzheimer's disease: A consecutive mixed memory clinic cohort study., PMID:40501109

Ghr-miR166b-GhHB14 Pair With GhDLO1 Partner Mediates Cotton Plant Defence Against Verticillium dahliae., PMID:40495269

Comparative transcriptomic and molecular interaction analysis of olive polyphenols: Unraveling their mechanisms in immune regulation and metabolic processes in adipocytes., PMID:40483856

Association of Alzheimer's disease concerns with amyloid burden and lifestyle behaviors in cognitively unimpaired older adults., PMID:40476544

Insights into pathophysiology, biomarkers, and therapeutics in tauopathies: Proceedings of the Tau2024 Global Conference., PMID:40437880

The value of triglyceride glucose-body mass index, fasting blood glucose to HDL-C ratio, and platelet to HDL-C ratio in predicting abdominal aortic calcification in maintenance hemodialysis patients., PMID:40419409

Growth hormone regulates deiodinase type 2 and 3 expression via GATA., PMID:40413916

Ubiquitin-proteasome system in the different stages of dominantly inherited Alzheimer's disease., PMID:40411302

Biodentine Stimulates Calcium-Dependent Osteogenic Differentiation of Mesenchymal Stromal Cells from Periapical Lesions., PMID:40362457

Relationship between use of anti-platelet agents, oral anti-coagulants, and Aβ burden with cerebral microhemorrhages in cognitively asymptomatic adults., PMID:40356042

METTL3-dependent m6A modification of GHR mRNA regulates mitochondrial function through mitochondrial biogenesis during myoblast differentiation., PMID:40344709

Novel evidence in vivo: Berberine ameliorated glucocorticoid-induced post-natal growth retardation by regulating the GH/IGF-1 axis through KMT1A downregulation., PMID:40328339

The growth hormone/IGF-1 axis is a risk factor for long-term kidney allograft failure., PMID:40327402

Association of Growth Hormone Receptor Gene Polymorphisms (rs6180, rs6182, rs6184) with Skeletal Class III Malocclusion and Prognathic Mandibles in the Deutero-Malay Race., PMID:40311632

Combination of growth hormone receptor antagonist and radiation reduces tumour growth in a lung cancer xenograft model., PMID:40298337

High glycosylated serum protein to high density lipoprotein cholesterol ratios are predictive of worse acute on chronic liver failure prognoses., PMID:40274908

Aβ42/40 and p-tau 181 as disease biomarkers in atypical Alzheimer's disease., PMID:40267266

Characterization of a direct role of GnRHs in the control of spermiogenesis and steroidogenesis in the small-spotted catshark Scyliorhinus canicula., PMID:40254036

The CentiMarker project: Standardizing quantitative Alzheimer's disease fluid biomarkers for biologic interpretation., PMID:40235082

GH-Releasing Hormone Neurons Regulate the Hypothalamic-Pituitary-Somatotropic Axis via Short-Loop Negative Feedback., PMID:40172534

Serum of interleukin-6 and procalcitonin as early diagnostic markers for the identification of poor hematopoietic reconstitution following allogeneic hematopoietic stem cell transplantation., PMID:40168545

Safety and efficacy of long-term gantenerumab treatment in dominantly inherited Alzheimer's disease: an open-label extension of the phase 2/3 multicentre, randomised, double-blind, placebo-controlled platform DIAN-TU trial., PMID:40120616

Relation of Alzheimer's disease-related TDP-43 proteinopathy to metrics from diffusion tensor imaging (DTI) and neurite orientation dispersion and density imaging (NODDI)., PMID:40088623

Comprehensive cross-sectional and longitudinal comparisons of plasma glial fibrillary acidic protein and neurofilament light across FTD spectrum disorders., PMID:40075459

Additive effects of ALXN2420, a GH receptor antagonist, and octreotide on IGF1 suppression in vivo., PMID:40067863

Considerations in the clinical use of amyloid PET and CSF biomarkers for Alzheimer's disease., PMID:40042435

Genome-wide identification and characterization of FORMIN gene family in cotton (Gossypium hirsutum L.) and their expression profiles in response to multiple abiotic stress treatments., PMID:40029892

A humanised ACE2, TMPRSS2, and FCGRT mouse model reveals the protective efficacy of anti-receptor binding domain antibodies elicited by SARS-CoV-2 hybrid immunity., PMID:40020261

Seasonal Influences on Human Placental Transcriptomes Associated with Spontaneous Preterm Birth., PMID:39996774

Changes in energy homeostasis, gut peptides, and gut microbiota in Emiratis with obesity after bariatric surgery., PMID:39992945

Disclosure of elevated amyloid status is not associated with long-term suicidality in a preclinical AD trial., PMID:39988989

Machine learning prediction of tau-PET in Alzheimer's disease using plasma, MRI, and clinical data., PMID:39985487

SCD-plus features and AD biomarkers in cognitively unimpaired samples: A meta-analytic approach for nine cohort studies., PMID:39985404

Genomic Tools for Medicinal Properties of Goat Milk for Cosmetic and Health Benefits: A Narrative Review., PMID:39940662

Influence of alpha-synuclein on glucose metabolism in Alzheimer's disease continuum: Analyses of α-synuclein seed amplification assay and FDG-PET., PMID:39935389

Early fecal microbiota transplantation continuously improves chicken growth performance by inhibiting age-related Lactobacillus decline in jejunum., PMID:39930537

Detection of Alzheimer Neuropathology in Alzheimer and Non-Alzheimer Clinical Syndromes With Blood-Based Biomarkers., PMID:39928343

SOCS2 inhibits the tumorigenesis of GISTs and increases the sensitivity of GISTs to imatinib by suppression of KIT activation., PMID:39922931

Repetitive Feeding-Challenge With Different Nutritional Densities on Markers of Gastrointestinal Function, Substrate Oxidation, and Endurance Exercise Performance., PMID:39914376

The Alzheimer's Association Global Biomarker Standardization Consortium (GBSC) plasma phospho-tau Round Robin study., PMID:39907496

Growth hormone signaling and clinical implications: from molecular to therapeutic perspectives., PMID:39904816

Painful diabetic neuropathy is associated with accelerated epigenetic aging., PMID:39847262

Ghrelin alleviates liver fibrosis by triggering HSCs ferroptosis via regulating injured hepatocyte-derived exosomal LncMALAT1/GPX4 pathway., PMID:39835702

White matter hyperintensities and TDP-43 pathology in Alzheimer's disease., PMID:39821594

Aarskog-Scott syndrome: a clinical study based on a large series of 111 male patients with a pathogenic variant in FGD1 and management recommendations., PMID:39798962

Extended Photoperiod Facilitated the Restoration of the Expression of GH-IGF Axis Genes in Submerged Rainbow Trout (Oncorhynchus mykiss)., PMID:39769354

Polymorphism of Genes Potentially Affecting Growth and Body Size Suggests Genetic Divergence in Wild and Domestic Reindeer (Rangifer tarandus) Populations., PMID:39766896

Searching and Using MobiDB Resource 6 to Explore Predictions and Annotations for Intrinsically Disordered Proteins., PMID:39718444

Bioinformatic approach to identifying causative missense polymorphisms in animal genomes., PMID:39701989

Growth hormone receptor in VGLUT2 or Sim1 cells regulates glycemia and insulin sensitivity., PMID:39700135

Datasheet
$ 360
Product specifications
50 μg 360 100 μg 580

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For research use only. Not for human or drug use.

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Recombinant Human GHR Protein, C-hFc-His (Active) [AHC84301]
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