Catalog No.
AHC44301
Biological activity
Measured in a cell proliferation assay using mouse myelogenous leukemia lymphoblast cells (NFS-60). The ED50 for this effect is 40-165 pg/mL.
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-Pro204
Nature
Recombinant
Endotoxin level
<0.1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
P09919
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
C17orf33, Lenograstim, CSF3, Pluripoietin, Filgrastim, Granulocyte colony-stimulating factor, GCSF, G-CSF
Combining RNA-seq, molecular docking and experimental verification to explore the mechanism of BAM15 as a potential drug for atherosclerosis., PMID:40247008
Cancer-associated fibroblasts secrete CSF3 to promote TNBC progression via enhancing PGM2L1-dependent glycolysis reprogramming., PMID:40185722
Discovering potential therapeutic targets in glioblastoma multiforme using a multi-omics approach., PMID:40168776
Harmine alleviates LPS-induced acute lung injury by inhibiting CSF3-mediated MAPK/NF-κB signaling pathway., PMID:40156005
Modulation of Macrophages TLR4-Mediated Transcriptional Response by Lacticaseibacillus rhamnosus CRL1505 and Lactiplantibacillus plantarum CRL1506., PMID:40141330
Dexamethasone vs. placebo modulation of the perioperative blood immune proteome in patients undergoing total knee arthroplasty., PMID:40119286
Naoqing formula alleviates cerebral ischemia/reperfusion injury induced inflammatory injury by regulating Csf3 mediated JAK/STAT pathway and macrophage polarization., PMID:40088744
Integrated analyses of metabolome, leaf anatomy, epigenome, and transcriptome under different light intensities reveal dynamic regulation of histone modifications on the high light adaptation in Camellia sinensis., PMID:40028698
CsMYB308 as a repressive transcription factor inhibits anthocyanin biosynthesis in tea plants., PMID:40020600
Colony-stimulating factor 3 and its receptor promote leukocyte immunoglobulin-like receptor B2 expression and ligands in gastric cancer., PMID:39958563
Response of photosynthetic capacity to ecological factors and its relationship with EGCG biosynthesis of tea plant (Camellia sinensis)., PMID:39953393
Comparison of immune responses to respiratory syncytial virus in infancy, childhood, and adulthood using an in vitro model of human respiratory infection., PMID:39849994
Bioinformatics analysis identifies key secretory protein-encoding differentially expressed genes in adipose tissue of metabolic syndrome., PMID:39819282
Inflammatory Response of THP1 and U937 Cells: The RNAseq Approach., PMID:39768153
Integrated Transcriptome and Metabolome Analysis Reveals Insights into Flavone and Flavonol Biosynthesis in Salicylic Acid-Induced Citrus Huanglongbing Tolerance., PMID:39723904
Transcriptomic analysis of key genes and signaling pathways in sepsis-associated intestinal mucosal barrier damage., PMID:39617276
Gammaherpesvirus Infection Stimulates Lung Tumor-Promoting Inflammation., PMID:39338937
Old drug, new use: Recent advances for G-CSF., PMID:39293182
Profiles of cytokines in patients with antineutrophil cytoplasmic antibody-associated vasculitis., PMID:39108259
The PerioGene North Study Uncovers Serum Proteins Related to Periodontitis., PMID:39101637
Altered expression of cytokines, chemokines, growth factors, and soluble receptors in patients with colorectal cancer, and correlation with treatment outcome., PMID:38954024
Comparing machine learning screening approaches using clinical data and cytokine profiles for COVID-19 in resource-limited and resource-abundant settings., PMID:38937503
Zinc Treatment of Tea Plants Improves the Synthesis of Trihydroxylated Catechins via Regulation of the Zinc-Sensitive Protein CsHIPP3., PMID:38886187
Investigation of lactotransferrin messenger RNA expression levels as an anti-type 2 asthma biomarker., PMID:38797239
CSF3 aggravates acute exacerbation of pulmonary fibrosis by disrupting alveolar epithelial barrier integrity., PMID:38788452
Serum proteome signatures associated with ileal and colonic ulcers in Crohn's disease., PMID:38763457
Enhanced ApcMin/+ adenoma formation after epithelial CUL4B deletion by recruitment of myeloid-derived suppressor cells., PMID:38761506
Heterogeneity of immune cells and their communications unveiled by transcriptome profiling in acute inflammatory lung injury., PMID:38745657
R2R3-MYB transcription factor CsMYB60 controls mature fruit skin color by regulating flavonoid accumulation in cucumber., PMID:38733630
Exploring causal correlations between inflammatory cytokines and knee osteoarthritis: a two-sample Mendelian randomization., PMID:38698846
Correlating transcription and protein expression profiles of immune biomarkers following lipopolysaccharide exposure in lung epithelial cells., PMID:38652715
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease., PMID:38589621
Arginase inhibitor reduces fungal dissemination in murine pulmonary cryptococcosis by promoting anti-cryptococcal immunity., PMID:38581993
A flavonoid metabolon: cytochrome b5 enhances B-ring trihydroxylated flavan-3-ols synthesis in tea plants., PMID:38461478
The Role of Rv1476 in Regulating Stress Response and Intracellular Survival of Mycobacterium tuberculosis., PMID:38392218
Identification of a novel glioblastoma multiforme molecular subtype with poor prognosis and high immune infiltration based on oxidative stress-related genes., PMID:38363895
A comprehensive bioinformatics analysis identifies mitophagy biomarkers and potential Molecular mechanisms in hypertensive nephropathy., PMID:38334110
The Duality of Adiponectin: The Role of Sex in Atherosclerosis., PMID:38201205
Overcoming therapeutic resistance in oncolytic herpes virotherapy by targeting IGF2BP3-induced NETosis in malignant glioma., PMID:38167409
APPLICATION OF QUANTILE DISCRETIZATION AND BAYESIAN NETWORK ANALYSIS TO PUBLICLY AVAILABLE CYSTIC FIBROSIS DATA SETS., PMID:38160305
Immune response to zinc oxide inhalation in metal fume fever, and the possible role of IL-17f., PMID:38097754
ABCB1 Regulates Immune Genes in Breast Cancer., PMID:38020048
A cohort-based study of host gene expression: tumor suppressor and innate immune/inflammatory pathways associated with the HIV reservoir size., PMID:38019897
Pretreatment of UC-MSCs with IFN-α2 improves treatment of liver fibrosis by recruiting neutrophils., PMID:37980535
Endometrial fluid biomarkers and their potential as predictors of successful embryo implantation., PMID:37937060
HSP90, a Common Therapeutic Target for Suppressing Skin Injury Caused by Exposure to Chemically Diverse Classes of Blistering Agents., PMID:37914412
Extracellular proteins as potential biomarkers in Sepsis-related cerebral injury., PMID:37901226
Identification of Targets for Subsequent Treatment of Crohn's Disease Patients After Failure of Anti-TNF Therapy., PMID:37868830
Spatial transcriptomics reveal basal sex differences in supraoptic nucleus gene expression of adult rats related to cell signaling and ribosomal pathways., PMID:37858270
Defective monocyte plasticity and altered cAMP pathway characterize USB1-mutated poikiloderma with neutropenia Clericuzio type., PMID:37779259
For research use only. Not for human or drug use.
