Catalog No.
YHC06101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met2-Phe98
Predicted molecular weight
13.32 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P04080
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Liver thiol proteinase inhibitor, CPI-B, CST6, CSTB, STFB, Cystatin-B, Stefin-B
Effects of CSTB on in vitro maturation of ovine oocytes., PMID:40252273
Characterization of the Orphan Cytochrome P450 CYP135B1 from Mycobacterium tuberculosis: Involvement in Metabolism but Not in the Antibacterial Activity of the Antitubercular Drug SQ109., PMID:40176299
Cystatin B Promotes the Proliferation, Migration, and Invasion of Intrahepatic Cholangiocarcinoma., PMID:39996856
Exploring proteomic immunoprofiles: common neurological and immunological pathways in multiple sclerosis and type 1 diabetes mellitus., PMID:39901093
Single-cell transcriptomics analysis reveals dynamic changes and prognostic signature in tumor microenvironment of PDAC., PMID:39894886
Reduction of Cystatin B results in increased cathepsin B activity in disomic but not Trisomy 21 human cellular and mouse models., PMID:39841661
Haloacetonitriles Induce Structure-Related Cellular Toxicity Through Distinct Proteome Thiol Reaction Mechanisms., PMID:39830722
Homozygosity for a hypomorphic mutation in frizzled class receptor 5 causes syndromic ocular coloboma with microcornea in humans., PMID:39503780
Plastic nanoparticles interfere with extracellular vesicle pathway in primary astrocytes., PMID:39437516
Comparison of Peptidomes Extracted from Healthy Tissue and Tumor Tissue of the Parotid Glands and Saliva Samples., PMID:39201484
Plasma Olink Proteomics Reveals Novel Biomarkers for Prediction and Diagnosis in Dilated Cardiomyopathy with Heart Failure., PMID:39129220
Salivary biomarkers for the diagnosis of gastric cancer: a systematic review., PMID:39119128
Progression from healthy periodontium to gingivitis and periodontitis: Insights from bioinformatics-driven proteomics - A systematic review with meta-analysis., PMID:38873831
Capillary blood protein markers of posttraumatic headache in children after concussion., PMID:38457794
Image-defined risk factors associated with MYCN oncogene amplification in neuroblastoma and their association with overall survival., PMID:38436700
Biomarker cystatin B expression correlates with pathogenesis in cervical cancer., PMID:38436260
The Roles of Cystatin B in the Brain and Pathophysiological Mechanisms of Progressive Myoclonic Epilepsy Type 1., PMID:38247861
Large-scale gene expression changes in APP/PSEN1 and GFAP mutation models exhibit high congruence with Alzheimer's disease., PMID:38236817
CSTB gene replacement improves neuroinflammation, neurodegeneration and ataxia in murine type 1 progressive myoclonus epilepsy., PMID:38135787
Comparative proteomic analysis of cerebral cortex revealed neuroprotective mechanism of esculentoside A on Alzheimer's disease., PMID:38128868
Pathological Deficit of Cystatin B Impairs Synaptic Plasticity in EPM1 Human Cerebral Organoids., PMID:38087165
Two rare autosomal recessive neurological disorders identified by combined genetic approaches in a single consanguineous family with multiple offspring., PMID:38012464
Generation of a human induced pluripotent stem cell line (UEFi004-A) from a patient with progressive myoclonic epilepsy type 1 (EPM1)., PMID:37951142
Prognostic significance of collagen signatures at breast tumor boundary obtained by combining multiphoton imaging and imaging analysis., PMID:37606817
Cathepsin B abundance, activity and microglial localisation in Alzheimer's disease-Down syndrome and early onset Alzheimer's disease; the role of elevated cystatin B., PMID:37580797
Negative myoclonus causes locomotory disability in progressive myoclonus epilepsy type EPM1- Unverricht-Lundborg disease., PMID:37536959
Updated skin transcriptomic atlas depicted by reciprocal contribution of single-nucleus RNA sequencing and single-cell RNA sequencing., PMID:37407342
Single-cell sequencing analysis of peripheral blood in patients with moyamoya disease., PMID:37400835
Progressive mitochondrial dysfunction in cerebellar synaptosomes of cystatin B-deficient mice., PMID:37251643
Real or fake? Measuring the impact of protein annotation errors on estimates of domain gain and loss events., PMID:37151482
Myeloperoxidase Inhibition Reverses Biomarker Profiles Associated With Clinical Outcomes in HFpEF., PMID:37140510
CeGAL: Redefining a Widespread Fungal-Specific Transcription Factor Family Using an In Silico Error-Tracking Approach., PMID:37108879
Salivary annexin A1: A candidate biomarker for periodontitis., PMID:36935103
Transcriptional activation of CSTB gene expression by transcription factor Sp3., PMID:36745972
Expression and Regulation of a Novel Decidual Cells-Derived Estrogen Target during Decidualization., PMID:36613747
Cystatin B increases autophagic flux by sustaining proteolytic activity of cathepsin B and fuels glycolysis in pancreatic cancer: CSTB orchestrates autophagy and glycolysis in PDAC., PMID:36495123
Multi-omics analyses identify molecular signatures with prognostic values in different heart failure aetiologies., PMID:36493852
Decreased CSTB, RAGE, and Axl Receptor Are Associated with Zika Infection in the Human Placenta., PMID:36429055
Protein biomarkers of cardiac remodeling and inflammation associated with HFpEF and incident events., PMID:36418363
Insights into the Genetic Profile of Two Siblings Affected by Unverricht-Lundborg Disease Using Patient-Derived hiPSCs., PMID:36359887
GENES EXPRESSION AND SERUM BIOMARKERS FOR DIAGNOSIS OF HEPATOCELLULAR CARCINOMA, CIRRHOSIS AND HEPATITIS C., PMID:36102438
From Bowen disease to cutaneous squamous cell carcinoma: eight markers were verified from transcriptomic and proteomic analyses., PMID:36085041
Bone Marrow Mesenchymal Stem Cells Derived from Juvenile Macaques Reversed the Serum Protein Expression Profile in Aged Macaques., PMID:35996242
Probing the Ubiquitination-Mediated Function of Epithelial Sodium Channel in A549 Cells., PMID:35894469
The BCC7 Protein Contributes to the Toxoplasma Basal Pole by Interfacing between the MyoC Motor and the IMC Membrane Network., PMID:35682673
The Role of NMP22 and CSTB Levels in Predicting Postoperative Recurrence of Bladder Cancer., PMID:35647202
Evaluation of CSTB and DMBT1 expression in saliva of gastric cancer patients and controls., PMID:35488257
Identification of the shared gene signatures and pathways between sarcopenia and type 2 diabetes mellitus., PMID:35271662