Catalog No.
YHC05601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp16-Ser148
Predicted molecular weight
17.16 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P04054
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Phospholipase A2, PLA2G1B, Group IB phospholipase A2, PLA2A, PPLA2, Phosphatidylcholine 2-acylhydrolase 1B, PLA2
Periodic dietary restriction of animal products induces metabolic reprogramming in humans with effects on cardiometabolic health., PMID:40225784
Associations between skeletal muscle mass and elevated blood pressure are independent of body fat: a cross-sectional study in young adult women of African ancestry., PMID:39817427
Identifying potential targets for preventing cancer progression through the PLA2G1B recombinant protein using bioinformatics and machine learning methods., PMID:39019365
Identification of biomarkers and potential therapeutic targets for pancreatic cancer by proteomic analysis in two prospective cohorts., PMID:38754433
Exploration of the Mechanism of Kaempferol in the Treatment of Cervical Cancer-based on Metabolomics and Network Pharmacology., PMID:38062663
Inactivation of Group 1B Phospholipase A2 Enhances Disease Recovery and Reduces Experimental Colitis in Mice., PMID:38003345
Establishment, characterization, and drug screening of low-passage patient individual non-small cell lung cancer in vitro models including the rare pleomorphic subentity., PMID:37228492
Combination of metabolomics and network pharmacology analysis to decipher the mechanisms of total flavonoids of Litchi seed against prostate cancer., PMID:37167442
The activities and mechanisms of intestinal microbiota metabolites of TCM herbal ingredients could be illustrated by a strategy integrating spectrum-effects, network pharmacology, metabolomics and molecular docking analysis: Platycodin D as an example., PMID:37094423
Proteomic Differences Between the Ovulatory and Anovulatory Sides of the Mare's Follicular and Oviduct Fluid., PMID:36592664
TAT&RGD Peptide-Modified Naringin-Loaded Lipid Nanoparticles Promote the Osteogenic Differentiation of Human Dental Pulp Stem Cells., PMID:35924260
Microbial Protein Binding to gC1qR Drives PLA2G1B-Induced CD4 T-Cell Anergy., PMID:35392090
Mechanism of Lycopodii herba for RA-ILD using integrated metabolomics and network pharmacology., PMID:35367217
Genetic analysis of pancreatic phospholipase A2 (PLA2G1B) in patients with chronic pancreatitis., PMID:35031208
Proteomic analysis of serum in workers exposed to diesel engine exhaust., PMID:34894159
Short Linear Motifs Characterizing Snake Venom and Mammalian Phospholipases A2., PMID:33923919
Mechanism of rutaecarpine on ethanol-induced acute gastric ulcer using integrated metabolomics and network pharmacology., PMID:33773465
sPLA2-IB Level Correlates with Hyperlipidemia and the Prognosis of Idiopathic Membranous Nephropathy., PMID:32862379
Ontogeny of Expression and Activity of Digestive Enzymes and Establishment of gh/igf1 Axis in the Omnivorous Fish Chelon labrosus., PMID:32443440
PLA2G1B is involved in CD4 anergy and CD4 lymphopenia in HIV-infected patients., PMID:32436864
Interleukin-17A/F1 Deficiency Reduces Antimicrobial Gene Expression and Contributes to Microbiome Alterations in Intestines of Japanese medaka (Oryzias latipes)., PMID:32256492
Key genes associated with pancreatic cancer and their association with outcomes: A bioinformatics analysis., PMID:31173193
Exogenous phospholipase A2 affects inflammatory gene expression in primary bovine mammary epithelial cells., PMID:31038092
Pancreatic duct-like cell line derived from pig embryonic stem cells: expression of uroplakin genes in pig pancreatic tissue., PMID:30868438
Therapeutic reduction of lysophospholipids in the digestive tract recapitulates the metabolic benefits of bariatric surgery and promotes diabetes remission., PMID:30087032
Feeder-cell-independent culture of the pig embryonic stem cell-derived exocrine pancreatic cell line, PICM-31., PMID:29442225
Identification of genes highly downregulated in pancreatic cancer through a meta-analysis of microarray datasets: implications for discovery of novel tumor-suppressor genes and therapeutic targets., PMID:29288362
Epithelial-Cell-Derived Phospholipase A2 Group 1B Is an Endogenous Anthelmintic., PMID:29024642
Identification of feature genes for smoking-related lung adenocarcinoma based on gene expression profile data., PMID:27994470
Tamoxifen prevents apoptosis and follicle loss from cyclophosphamide in cultured rat ovaries., PMID:25833159
Source and role of intestinally derived lysophosphatidic acid in dyslipidemia and atherosclerosis., PMID:25646365
Gene profiling of human VEGF signaling pathways in human endothelial and retinal pigment epithelial cells after anti VEGF treatment., PMID:25201034
Changes in metabolite profiles caused by genetically determined obesity in mice., PMID:24772056
Group 1B phospholipase A₂ inactivation suppresses atherosclerosis and metabolic diseases in LDL receptor-deficient mice., PMID:24747111
Nonbactericidal secreted phospholipase A2s are potential anti-inflammatory factors in the mammary gland., PMID:24091988
Antiviral activity of glycyrrhizin against hepatitis C virus in vitro., PMID:23874843
Deficiency of phospholipase A2 receptor exacerbates ovalbumin-induced lung inflammation., PMID:23817419
Activated amelogenin Y-linked (AMELY) regulation and angiogenesis in human hepatocellular carcinoma by biocomputation., PMID:23426651
Diverse regulation of retinal pigment epithelium phagocytosis of photoreceptor outer segments by calcium-independent phospholipase A₂, group VIA and secretory phospholipase A₂, group IB., PMID:22680611
Tissue-specific transplantation antigen P35B (TSTA3) immune response-mediated metabolism coupling cell cycle to postreplication repair network in no-tumor hepatitis/cirrhotic tissues (HBV or HCV infection) by biocomputation., PMID:22528125
Isoforms of secretory group two phospholipase A (sPLA2) in mouse ocular surface epithelia and lacrimal glands., PMID:22467583
Surfactant protein B inhibits secretory phospholipase A2 hydrolysis of surfactant phospholipids., PMID:22037357
Group 1B phospholipase A₂ deficiency protects against diet-induced hyperlipidemia in mice., PMID:21908646
Group IVA phospholipase A2 regulates testosterone biosynthesis by murine Leydig cells and is required for timely sexual maturation., PMID:21762109
Estrogens and selective estrogen receptor modulators regulate gene and protein expression in the mesenteric arteries., PMID:21658471
Effect of decreasing intraluteal progesterone on sensitivity of the early porcine corpus luteum to the luteolytic actions of prostaglandin F2alpha., PMID:20739670
Isolation of genes involved in pancreas regeneration by subtractive hybridization., PMID:20536387
The phospholipase A(2) inhibitor methyl indoxam suppresses diet-induced obesity and glucose intolerance in mice., PMID:19563529
Fluorescence in situ hybridization and chromosomal organization of the sirtuin 4 gene (Sirt4) in the mouse., PMID:19306844
Structural insight into the activation mechanism of human pancreatic prophospholipase A2., PMID:19297324
For research use only. Not for human or drug use.
