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InVivoMAb Anti-Influenza A/B virus NA/Neuraminidase Broad-Neutralizing Antibody (Iv0283)

Catalog #:   VVV24006 Specific References (31) DATASHEET
Host species: Human
Isotype: IgG1, kappa
Applications: ELISA, Neutralization
Accession: A0A2D3I2L6, A0A0C4ZKQ4, P03468, Q6DPL2, Q910S0, H8P392, P03474, G8JJM2, C0LT34, R9WY37, A0A1X9RX69
Overview

Catalog No.

VVV24006

Species reactivity

Influenza A virus (A/Brisbane/59-MA/2007(H1N1))(A0A2D3I2L6), Influenza A virus (strain swl A/California/04/2009 H1N1) (A0A0C4ZKQ4), (P03468) Influenza A virus (strain A/Puerto Rico/8/1934 H1N1), Influenza A virus (strain A/Vietnam/1203/2004 H5N1) (Q6DPL2), Influenza A virus (strain A/Hong Kong/1/1968 H3N2) (Q910S0), Influenza A virus (A/Fujian/411/2002(H3N2)) (H8P392), Influenza B virus (strain B/Lee/1940) (P03474), Influenza B virus (B/Wisconsin/01/2010) (G8JJM2), Influenza B virus (B/Brisbane/60/2008) (C0LT34), Influenza B virus (B/Texas/02/2013) (R9WY37), Influenza B virus (B/Colorado/06/2017) (A0A1X9RX69)

Host species

Human

Isotype

IgG1, kappa

Clonality

Monoclonal

Target

NA, Neuraminidase

Concentration

2.68 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

A0A2D3I2L6, A0A0C4ZKQ4, P03468, Q6DPL2, Q910S0, H8P392, P03474, G8JJM2, C0LT34, R9WY37, A0A1X9RX69

Applications

ELISA, Neutralization

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

Iv0283

Data Image
References

A monoclonal anti-hemagglutinin stem antibody modified with zanamivir protects against both influenza A and B viruses., PMID:40193611

Broadly protective bispecific antibodies that simultaneously target influenza virus hemagglutinin and neuraminidase., PMID:38899870

Fc-Effector-Independent in vivo Activity of a Potent Influenza B Neuraminidase Broadly Neutralizing Antibody., PMID:37515226

Highly Cross-Reactive and Protective Influenza A Virus H3N2 Hemagglutinin- and Neuraminidase-Specific Human Monoclonal Antibodies., PMID:37318331

Multi-Influenza HA Subtype Protection of Ferrets Vaccinated with an N1 COBRA-Based Neuraminidase., PMID:36680224

A broadly protective human monoclonal antibody targeting the sialidase activity of influenza A and B virus neuraminidases., PMID:36329075

Characterization of Immune Response towards Generation of Universal Anti-HA-Stalk Antibodies after Immunization of Broiler Hens with Triple H5N1/NA-HA-M1 VLPs., PMID:35458460

Supplementation of H7N9 Virus-Like Particle Vaccine With Recombinant Epitope Antigen Confers Full Protection Against Antigenically Divergent H7N9 Virus in Chickens., PMID:35265069

Universal Influenza Virus Neuraminidase Vaccine Elicits Protective Immune Responses against Human Seasonal and Pre-pandemic Strains., PMID:34160258

Structure-Based Modification of an Anti-neuraminidase Human Antibody Restores Protection Efficacy against the Drifted Influenza Virus., PMID:33024040

Broadly protective human antibodies that target the active site of influenza virus neuraminidase., PMID:31649200

Elicitation of Broadly Protective Antibodies following Infection with Influenza Viruses Expressing H1N1 Computationally Optimized Broadly Reactive Hemagglutinin Antigens., PMID:31022693

Enhanced cross-lineage protection induced by recombinant H9N2 avian influenza virus inactivated vaccine., PMID:30797637

Highly immunogenic influenza virus-like particles containing B-cell-activating factor (BAFF) for multi-subtype vaccine development., PMID:30738089

Antibody Determinants of Influenza Immunity., PMID:30715373

Neuraminidase inhibition contributes to influenza A virus neutralization by anti-hemagglutinin stem antibodies., PMID:30683737

Immunodominance and Antigenic Variation of Influenza Virus Hemagglutinin: Implications for Design of Universal Vaccine Immunogens., PMID:30535315

Mutations in Influenza A Virus Neuraminidase and Hemagglutinin Confer Resistance against a Broadly Neutralizing Hemagglutinin Stem Antibody., PMID:30381484

Computational screening of known broad-spectrum antiviral small organic molecules for potential influenza HA stem inhibitors., PMID:30180218

Intra-seasonal antibody repertoire analysis of a subject immunized with an MF59®-adjuvanted pandemic 2009 H1N1 vaccine., PMID:30055967

Immunogenicity and Protection Against Influenza H7N3 in Mice by Modified Vaccinia Virus Ankara Vectors Expressing Influenza Virus Hemagglutinin or Neuraminidase., PMID:29599502

Development of Clade-Specific and Broadly Reactive Live Attenuated Influenza Virus Vaccines against Rapidly Evolving H5 Subtype Viruses., PMID:28490598

Nanostructured glycan architecture is important in the inhibition of influenza A virus infection., PMID:27775724

Broadly neutralizing anti-influenza antibodies require Fc receptor engagement for in vivo protection., PMID:26731473

Protection against H5N1 Influenza Virus Induced by Matrix-M Adjuvanted Seasonal Virosomal Vaccine in Mice Requires Both Antibodies and T Cells., PMID:26696245

Progress on adenovirus-vectored universal influenza vaccines., PMID:25876176

Intranasal adenovirus-vectored vaccine for induction of long-lasting humoral immunity-mediated broad protection against influenza in mice., PMID:24920793

An influenza N1 neuraminidase-specific monoclonal antibody with broad neuraminidase inhibition activity against H5N1 HPAI viruses., PMID:21922687

Influenza vaccine immunology., PMID:21198671

A pandemic influenza H1N1 live vaccine based on modified vaccinia Ankara is highly immunogenic and protects mice in active and passive immunizations., PMID:20808939

An enzymatic virus-like particle assay for sensitive detection of virus entry., PMID:19879300

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1486

Contact Information

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Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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InVivoMAb Anti-Influenza A/B virus NA/Neuraminidase Broad-Neutralizing Antibody (Iv0283) [VVV24006]
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