Catalog No.
EHC04301
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-Ala638
Predicted molecular weight
72.34 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>70% as determined by SDS-PAGE.
Accession
P03952
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Plasma prekallikrein, KLK3, Fletcher factor, KLKB1, Kininogenin, Plasma kallikrein, PKK
Potential therapeutic targets for deep vein thrombosis: A proteome-wide Mendelian randomization study., PMID:40462713
Enhancement of plasma kallikrein specificity of antitrypsin variants identified by phage display and partial reversion., PMID:40075385
Plasma Proteomic Assessment of Calcific Aortic Valve Disease in Older Adults., PMID:40008515
Platform-dependent effects of genetic variants on plasma APOL1 and their implications for kidney disease., PMID:39975113
CRISPR-Based Therapy for Hereditary Angioedema., PMID:39445704
Pharmacogenomics of clinical response to Natalizumab in multiple sclerosis: a genome-wide multi-centric association study., PMID:39264442
[Analysis of two consanguineous Chinese pedigrees affected with Hereditary prokallikrein deficiency and High molecular weight kininogen deficiency]., PMID:39217484
The trajectory of vesicular proteomic signatures from HBV-HCC by chitosan-magnetic bead-based separation and DIA-proteomic analysis., PMID:39207047
Identifying Potential Drug Targets for Keloid: A Mendelian Randomization Study., PMID:38797322
Combined transcriptomics and TMT-proteomics reveal abnormal complement and coagulation cascades in cow's milk protein allergy., PMID:38457985
CRISPR-Cas9 In Vivo Gene Editing of KLKB1 for Hereditary Angioedema., PMID:38294975
Clinical Progress in Hepatic Targeting for Novel Prophylactic Therapies in Hereditary Angioedema., PMID:38142864
Proteomics Analysis of Serum Reveals Potential Biomarkers for Heart Failure Patients with Phlegm-Blood Stasis Syndrome., PMID:38048169
Biology of factor XI., PMID:37874916
Genomic selection pressure discovery using site-frequency spectrum and reduced local variability statistics in Pakistani Dera-Din-Panah goat., PMID:37750990
Proteome-wide mendelian randomization identifies causal plasma proteins in venous thromboembolism development., PMID:37537391
Circulating extracellular vesicles promote recovery in a preclinical model of intracerebral hemorrhage., PMID:37090418
PGK1 modulates balance between pro- and anti-inflammatory cytokines by interacting with ITI-H4., PMID:36841032
KLKB1 and CLSTN2 are associated with HDL-mediated cholesterol efflux capacity in a genome-wide association study., PMID:36812656
Severe high-molecular-weight kininogen deficiency: clinical characteristics, deficiency-causing KNG1 variants, and estimated prevalence., PMID:36700498
[Analysis of differentially expressed microRNA and protein expression profiles carried by exosomes in the plasma of patients with Takayasu's arteritis]., PMID:36631039
Prion Mutations in Republic of Republic of Korea, China, and Japan., PMID:36614069
Characterization of a proteomic profile associated with organ dysfunction and mortality of sepsis and septic shock., PMID:36459524
[Matrix metalloproteinase 14 and plasma kallikrein 1 may be potential biomarkers in the diagnosis and treatment of sepsis: a proteomics and bioinformatics analysis]., PMID:36100402
The therapeutic relevance of the Kallikrein-Kinin axis in SARS-cov-2-induced vascular pathology., PMID:35930434
Searching for Genetic Biomarkers for Hereditary Angioedema Due to C1-Inhibitor Deficiency (C1-INH-HAE)., PMID:35873600
Impaired Kallikrein-Kinin System in COVID-19 Patients' Severity., PMID:35812405
Plasma proteomic analysis of association between atrial fibrillation, coronary microvascular disease and heart failure., PMID:35600285
Proteomics discovery of pulmonary hypertension biomarkers: Insulin-like growth factor binding proteins are associated with disease severity., PMID:35514776
The Dysregulation of the Renin-Angiotensin System in COVID-19 Studied by Serum Proteomics: Angiotensinogen Increases with Disease Severity., PMID:35458690
Genetics of osteopontin in patients with chronic kidney disease: The German Chronic Kidney Disease study., PMID:35385482
Ablation of Plasma Prekallikrein Decreases Low-Density Lipoprotein Cholesterol by Stabilizing Low-Density Lipoprotein Receptor and Protects Against Atherosclerosis., PMID:35189703
A review of oral kallikrein inhibitor berotralstat for hereditary angioedema., PMID:35188140
Differential proteomic analysis demonstrates follicle fluid participate immune reaction and protein translation in yak., PMID:35031034
Prekallikrein deficiency due to homozygous KLKB1(+) mutation c.444_445insT (p.Ser151PhefsTer34)., PMID:34847617
Prenatal diagnosis of a 4.5-Mb deletion at chromosome 4q35.1q35.2: Case report and literature review., PMID:34794455
Serum KLKB1 as a Potential Prognostic Biomarker for Hepatocellular Carcinoma Based on Data-Independent Acquisition and Parallel Reaction Monitoring., PMID:34676182
Systematic Construction and Validation of a Prognostic Model for Hepatocellular Carcinoma Based on Immune-Related Genes., PMID:34671598
Genetic Profile of Endotoxemia Reveals an Association With Thromboembolism and Stroke., PMID:34668383
Plasma Kallikrein as a Modulator of Liver Injury/Remodeling., PMID:34566641
Kallikrein augments the anticoagulant function of the protein C system in thrombin generation., PMID:34532976
The Inclusion Principles of Human Embryos in the WOW-Based Time-Lapse System: A Retrospective Cohort Study., PMID:34381419
Cardiovascular Biomarkers of Obesity and Overlap With Cardiometabolic Dysfunction., PMID:34219465
Genome-wide association study of cardiac troponin I in the general population., PMID:33961016
Centyrin ligands for extrahepatic delivery of siRNA., PMID:33601052
c.451dupT in KLKB1 is common in Nigerians, confirming a higher prevalence of severe prekallikrein deficiency in Africans compared to Europeans., PMID:33073460
Optimizing PEG-Extended Apelin Analogues as Cardioprotective Drug Leads: Importance of the KFRR Motif and Aromatic Head Group for Improved Physiological Activity., PMID:33001648
COVID-19-Related Coagulopathy-Is Transferrin a Missing Link?, PMID:32751741
Systemic Proteome Alterations Linked to Early Stage Pancreatic Cancer in Diabetic Patients., PMID:32545216
Bioinformatics analysis of key biomarkers and potential molecular mechanisms in hepatocellular carcinoma induced by hepatitis B virus., PMID:32443377
For research use only. Not for human or drug use.
