Catalog No.
YVV08903
Expression system
E. coli
Species
Human papillomavirus type 18
Protein length
Met1-Gln105
Predicted molecular weight
12.82 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P06788
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
E7, Protein E7
Development of an innovative approach for early diagnosis of cervical cancer using TCR‑like antibodies targeting HPV18 E6 and E7 peptides., PMID:40476553
Crosstalk Between the Oncoproteins of High-Risk Human Papillomaviruses Types 16 and 18 in Colorectal Cancer Cell Models., PMID:40468102
Molecular Insights into HPV-Driven Cervical Cancer: Oncoproteins, Immune Evasion, and Epigenetic Modifications., PMID:40431173
Boosting immune response against cervical cancer: A combined approach using oncolytic virus and targeted therapies., PMID:40403026
Human papillomavirus E1 proteins inhibit RIG-I/MDA5-MAVS, TLR3-TRIF, cGAS-STING, and JAK-STAT signaling pathways to evade innate antiviral immunity., PMID:40330484
Human papilloma virus (HPV) mediated cancers: an insightful update., PMID:40301924
Human papillomavirus E2 proteins suppress innate antiviral signaling pathways., PMID:40264759
Astragalin inhibits the proliferation of high-risk HPV-positive cervical epithelial cells and attenuates malignant cervical lesions., PMID:40124127
Drosophila model of HPV18-Induced pathogenesis reveals a role for E6 oncogene in regulation of NF-κB and Wnt to inhibit apoptosis., PMID:40074036
KAT8 facilitates the proliferation of cancer cells through enhancing E7 function in HPV-associated cervical cancer., PMID:39989021
Oncoproteins E6/E7 of the human papillomavirus types 16 & 18 synergize in modulating oncogenes and tumor suppressor proteins in colorectal cancer., PMID:39815804
Molecular analysis of HPV16 and HPV18 oncogenes in oral squamous cell carcinoma: Structural, transcriptomic and in vitro insights., PMID:39807101
DARPin-induced reactivation of p53 in HPV-positive cells., PMID:39789211
Designing of an mRNA vaccine against high-risk human papillomavirus targeting the E6 and E7 oncoproteins exploiting immunoinformatics and dynamic simulation., PMID:39761277
Comparative efficacy of HPV 16/18 DNA and E6/E7 mRNA testing in detecting high-grade cervical lesions (CIN2+) in women with cervical biopsies., PMID:39733635
Improved efficacy of therapeutic HPV DNA vaccine using intramuscular injection with electroporation compared to conventional needle and needle-free jet injector methods., PMID:39722048
Human Papillomavirus Infection and Autoimmune Diseases: A Two-Sample Bidirectional Mendelian Randomization Study., PMID:39618109
The Distribution of HR-HPV E6/E7 DNA and mRNA by Histological Grade and the Clinical Performance for Detection of Cervical Cancer and Precancer., PMID:39540331
The anti-tumor efficacy of a recombinant oncolytic herpes simplex virus mediated CRISPR/Cas9 delivery targeting in HPV16-positive cervical cancer., PMID:39536909
Detection of transcriptionally active high-risk human papillomavirus in patients with oesophageal carcinoma by real-time PCR., PMID:39412909
Recombinant adenoviruses expressing HPV16/18 E7 upregulate the HDAC6 and DNMT3B genes in C33A cells., PMID:39411320
PRMT1 Modulates Alternative Splicing to Enhance HPV18 mRNA Stability and Promote the Establishment of Infection., PMID:39386465
Signaling pathways in HPV-induced cervical cancer: Exploring the therapeutic promise of RNA modulation., PMID:39357186
HPV18 E7 inhibits LATS1 kinase and activates YAP1 by degrading PTPN14., PMID:39248565
HPV 16/18 E7 oncoprotein detection as a promising triage strategy for HPV 16/18-positive patients: A prospective multicenter study with a 2-year follow up., PMID:39244722
No genetic causal association between human papillomavirus and lung cancer risk: a bidirectional two-sample Mendelian randomization analysis., PMID:39227966
Microfluid biosensor for detection of hpv in patient scraping samples: Determining E6 and E7 oncogenes., PMID:39146929
HPV18 E6/E7 activates Ca2+ influx to promote the malignant progression of cervical cancer by inhibiting Ca2+ binding protein 1 expression., PMID:39113388
Immunoinformatics approach for design novel multi-epitope prophylactic and therapeutic vaccine based on capsid proteins L1 and L2 and oncoproteins E6 and E7 of human papillomavirus 16 and human papillomavirus 18 against cervical cancer., PMID:39039819
Comparison of preclinical efficacy of immunotherapies against HPV-induced cancers., PMID:38978164
Genetic variability of human papillomavirus type 18 based on E6, E7 and L1 genes in central China., PMID:38970084
Tirbanibulin decreases cell proliferation and downregulates protein expression of oncogenic pathways in human papillomavirus containing HeLa cells., PMID:38967656
Advances in human papillomavirus detection and molecular understanding in head and neck cancers: Implications for clinical management., PMID:38884391
Development of an mRNA-based therapeutic vaccine mHTV-03E2 for high-risk HPV-related malignancies., PMID:38715363
HPV oncogenes expressed from only one of multiple integrated HPV DNA copies drive clonal cell expansion in cervical cancer., PMID:38624210
Biplex quantitative PCR to detect transcriptionally active human papillomavirus 16 from patient saliva., PMID:38600473
Antibodies against high-risk human papillomavirus proteins as markers for noncervical HPV-related cancers in a Black South African population, according to HIV status., PMID:38577820
Distribution of human papillomavirus among Vietnamese women with cervical cancer and unusual genetic variability of HPV16., PMID:38520797
Immunogenicity and effectiveness of an mRNA therapeutic vaccine for HPV-related malignancies., PMID:38514186
HPV18 E7 inhibits LATS1 kinase and activates YAP1 by degrading PTPN14., PMID:38496413
HLA-class II restricted TCR targeting human papillomavirus type 18 E7 induces solid tumor remission in mice., PMID:38480731
Three-dimensional chromatin analysis reveals Sp1 as a mediator to program and reprogram HPV-host epigenetic architecture in cervical cancer., PMID:38471646
Bioinformatics analysis of photoexcited natural flavonoid glycosides as the inhibitors for oropharyngeal HPV oncoproteins., PMID:38466452
Structural analysis of PTPN21 reveals a dominant-negative effect of the FERM domain on its phosphatase activity., PMID:38416831
Evaluation of HPV 16 and HPV 18 Oncoprotein Expression as Alternative Diagnostic Tools in Cervical Lesion., PMID:38415538
ErbB2/HER2 receptor tyrosine kinase regulates human papillomavirus promoter activity., PMID:38370412
Human papillomavirus type 16 E7 promotes cell viability and migration in cervical cancer by regulating the miR-23a/HOXC8 axis., PMID:38348790
HPV16 E6 Oncogene Contributes to Cancer Immune Evasion by Regulating PD-L1 Expression through a miR-143/HIF-1a Pathway., PMID:38257813
Characteristics of Cervical Cancer Caused by the Human Papillomavirus 18 and Its Genetic Variations in Vietnamese Women., PMID:38176603
Activating STING/TBK1 suppresses tumor growth via degrading HPV16/18 E7 oncoproteins in cervical cancer., PMID:38007552
For research use only. Not for human or drug use.
