Catalog No.
YHC02601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ala61
Predicted molecular weight
32.88 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P02795
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MT2, MT-2, MT2A, Metallothionein-2A, Metallothionein-II, Metallothionein-2, CES1, MT-II
Suppression of pseudogene MT2P1 transcription induced by E2F7 inhibits hepatocellular carcinoma cell proliferation and facilitates apoptosis via preserving its parental gene., PMID:40407049
Gender-Dependent Effect of Progesterone on the Expression of Metallothionein Genes in Rat Inguinal Adipose Tissue., PMID:40362306
Metallothionein 2A enhances the yes-associated protein 1 signaling pathway to promote small-cell lung cancer metastasis., PMID:40260063
p53-binding Protein Inhibits Intracellular Reactive Oxygen Species by Increasing the Expression of Metallothioneins., PMID:40155029
Knockdown of SLC7A5 inhibits malignant progression and attenuates oxaliplatin resistance in gastric cancer by suppressing glycolysis., PMID:40133832
Chemoproteomics-Enabled De Novo Proteolysis Targeting Chimera Discovery Platform Identifies a Metallothionein Degrader to Probe Its Role in Cancer., PMID:39989026
MT2A promotes angiogenesis in chronically ischemic brains through a copper-mitochondria regulatory mechanism., PMID:39915841
Screening Methods to Discover the FDA-Approved Cancer Drug Encorafenib as Optimally Selective for Metallothionein Gene Loss Ovarian Cancer., PMID:39858588
Metallothionein-1A (MT1A) Gene Variability May Play a Role in Female Frailty: A Preliminary Study., PMID:39858562
Androgens differentially modulate glucocorticoid effects on adipose tissue and lean mass., PMID:39831834
Potential role of formononetin as a novel natural agent in Alzheimer's disease and osteoporosis comorbidity., PMID:39828895
Integrated transcriptomics and proteomics analysis of the impact of iodine‑125 in hepatocellular carcinoma., PMID:39791207
Integrative analysis and knowledgebase construction of key candidate genes and pathways in age-related macular degeneration., PMID:39615827
The mechanism underlying B-cell developmental dysfunction in Kawasaki disease based on single-cell transcriptomic sequencing., PMID:39507528
Gene expression profiles of neuroinflammatory responses in broad brain regions in rats repeatedly administered with N-methyl-N-nitrosourea for 28 days., PMID:39496385
A combined transcriptomics and proteomics approach reveals S100A4 as a potential biomarker for Graves' orbitopathy., PMID:39359477
Identification of genes contributing to attenuation of rat model of galactose-induced cataract by pyruvate., PMID:39219252
Blocking Metallothionein-2 Expression by Copper-Doped Carbon Dots Induces Cellular Antioxidant System Collapse for Antitumor Therapy., PMID:39141437
Synergistic Effects of Glutamine Deprivation and Metformin in Acute Myeloid Leukemia., PMID:39096478
Distinctive expression and cellular localisation of zinc homeostasis-related proteins in breast and prostate cancer cells., PMID:39047373
Comprehensive analysis of hub genes associated with cisplatin-resistance in ovarian cancer and screening of therapeutic drugs through bioinformatics and experimental validation., PMID:38987777
Circadian Rhythm Disruption in Hepatocellular Carcinoma Investigated by Integrated Analysis of Bulk and Single-Cell RNA Sequencing Data., PMID:38891936
Effects of Perioperative Zinc Supplementation on Copper Circulating Levels and Expression of Metallothionein and Copper Antioxidant Chaperone-1 in Leukocytes in Patients Undergoing CABG Surgery., PMID:38865064
In-depth organic mass cytometry reveals differential contents of 3-hydroxybutanoic acid at the single-cell level., PMID:38782922
Coccomyxa subellipsoidea KJ Components Enhance the Expression of Metallothioneins and Th17 Cytokines during Human T Cell Activation., PMID:38674685
Long-term 4-nonylphenol exposure drives cervical cell malignancy through MAPK-mediated ferroptosis inhibition., PMID:38657513
Identification of Novel Cuproptosis-Related Genes Mediating the Prognosis and Immune Microenvironment in Cholangiocarcinoma., PMID:38613350
Compensatory upregulation of MT2A alleviates neurogenic intermittent claudication through inhibiting activated p38 MAPK-mediated neuronal apoptosis., PMID:38546949
Differential Gene Regulatory Network Analysis between Azacitidine-Sensitive and -Resistant Cell Lines., PMID:38542276
Transcriptomic screening of novel targets of sericin in human hepatocellular carcinoma cells., PMID:38443583
Elucidating Hedgehog pathway's role in HNSCC progression: insights from a 6-gene signature., PMID:38409358
Equilibrium, kinetic, and thermodynamic studies on the biosorption of lead by human metallothionein gene-cloned bacteria as a novel biosorbent., PMID:38385887
RING induces cell cycle arrest and apoptosis in human breast cancer cells by regulating the HSF1/MT2A axis., PMID:37797799
Genetic Susceptibility to Neurotoxicity Related to Prenatal Inorganic Arsenic Exposure in Young Spanish Children., PMID:37787746
Single-cell transcriptome analysis revealing the intratumoral heterogeneity of ccRCC and validation of MT2A in pathogenesis., PMID:37713131
Metallothionein expression in the central nervous system in response to chronic heavy metal exposure: possible neuroprotective mechanism., PMID:37580456
lncRNA GHET1 regulates extravillous trophoblastic phenotype via EZH2/LSD1-mediated MT2A epigenetic suppression in pre-eclampsia., PMID:37548351
Zinc depletion induces JNK/p38 phosphorylation and suppresses Akt/mTOR expression in acute promyelocytic NB4 cells., PMID:37473591
Determinants of Survival with Combined HER2 and PD-1 Blockade in Metastatic Esophagogastric Cancer., PMID:37406106
Alterations in gene expressions of Caco-2 cell responses to LPS and ploy(I:C) stimulation., PMID:37304876
Annexin A1 is a cell-intrinsic metalloregulator of zinc in human ILC2s., PMID:37294636
Identification of critical genes associated with lead exposure based on in silico analysis., PMID:37178329
Intracellular Zinc Trafficking during Crotalus atrox Venom Wound Development., PMID:37047742
An Assessment of MT1A (rs11076161), MT2A (rs28366003) and MT1L (rs10636) Gene Polymorphisms and MT2 Concentration in Women with Endometrial Pathologies., PMID:36981043
Association of metallothionein 2A rs10636 with low mean corpuscular volume (MCV), low mean corpuscular haemoglobin (MCH) in healthy Taiwanese., PMID:36690679
Esterase D interacts with metallothionein 2A and inhibits the migration of A549 lung cancer cells in vitro., PMID:36649442
The Difference in Zinc Concentrations Required for Induction among Metallothionein Isoforms Can Be Explained by the Different MTF1 Affinities to MREs in Its Promoter., PMID:36613726
Effects of Long-Term Dietary Zinc Oxide Nanoparticle on Liver Function, Deposition, and Absorption of Trace Minerals in Intrauterine Growth Retardation Pigs., PMID:36585599
Gene Expression Linked to Reepithelialization of Human Skin Wounds., PMID:36555389
An Overlooked Hepcidin-Cadmium Connection., PMID:36555126
For research use only. Not for human or drug use.
