Catalog No.
YZZ06301
Expression system
E. coli
Species
Ambrosia artemisiifolia (Common ragweed)
Protein length
Ala26-Cys396
Predicted molecular weight
42.12 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
CBW30986.1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Amb a 1, Pectate lyase
Total protein concentration and stability of Amb a 1 in glycerinated ragweed sublingual immunotherapy stored at room temperature and refrigerated cold temperature., PMID:39469764
Combatting the antigenicity of common ragweed pollen and its primary allergen Amb a 1 with cold atmospheric pressure air plasma., PMID:39208626
Non-Specific Lipid Transfer Protein Amb a 6 Is a Source-Specific Important Allergenic Molecule in Ragweed Pollen., PMID:38928218
Insect Cell-Expressed Major Ragweed Allergen Amb a 1.01 Exhibits Similar Allergenic Properties to Its Natural Counterpart from Common Ragweed Pollen., PMID:38791214
The Sensitization Differences of Pollen Allergen Components in Patients with Asthma and/or Rhinitis in Southern China., PMID:38705139
Relationship between IgE Levels Specific for Ragweed Pollen Extract, Amb a 1 and Cross-Reactive Allergen Molecules., PMID:36835455
Ragweed Major Allergen Amb a 11 Recombinant Production and Clinical Implications., PMID:36671567
Ragweed pollen concentration predicts seasonal rhino-conjunctivitis and asthma severity in patients allergic to ragweed., PMID:36151263
A comprehensive analysis of the components of common weed pollen and related allergens in patients with allergic diseases in southern China., PMID:35633613
A new cysteine protease allergen from Ambrosia trifida pollen: proforms and mature forms., PMID:35598503
Effects of rAmb a 1-Loaded PLGA-PEG Nanoparticles in a Murine Model of Allergic Conjunctivitis., PMID:35163859
Design of peptides with high affinity binding to a monoclonal antibody as a basis for immunotherapy., PMID:34411692
Dectin-1 Controls TSLP-Induced Th2 Response by Regulating STAT3, STAT6, and p50-RelB Activities in Dendritic Cells., PMID:34305908
Molecular allergy diagnosis using pollen marker allergens and pollen panallergens: Five patterns seen in multiple test reactions to pollen extracts., PMID:34079923
Purification and biochemical characterization of Hel a 6, a cross-reactive pectate lyase allergen from Sunflower (Helianthus annuus L.) pollen., PMID:33214682
Ambrosia artemisiifolia L. temperature-responsive traits influencing the prevalence and severity of pollinosis: a study in controlled conditions., PMID:31023241
Ragweed allergy immunotherapy tablet MK-3641 (Ragwitek®) for the treatment of allergic rhinitis., PMID:30345820
Ragweed Pollen Allergy: Burden, Characteristics, and Management of an Imported Allergen Source in Europe., PMID:29788026
Chamber and Field Studies demonstrate Differential Amb a 1 Contents in Common Ragweed Depending on CO₂ Levels., PMID:29676075
Distinct epitope structures of defensin-like proteins linked to proline-rich regions give rise to differences in their allergenic activity., PMID:28960341
Amb a 1 isoforms: Unequal siblings with distinct immunological features., PMID:28464293
T Cell Epitope-Containing Domains of Ragweed Amb a 1 and Mugwort Art v 6 Modulate Immunologic Responses in Humans and Mice., PMID:28081194
Subpollen particles are rich carriers of major short ragweed allergens and NADH dehydrogenases: quantitative proteomic and allergomic study., PMID:28000951
Epinephrine Use in Clinical Trials of Sublingual Immunotherapy Tablets., PMID:27838323
Sequence conservation predicts T cell reactivity against ragweed allergens., PMID:27359111
Potential health risk of allergenic pollen with climate change associated spreading capacity: Ragweed and olive sensitization in two German federal states., PMID:26906017
Mesoscale atmospheric transport of ragweed pollen allergens from infected to uninfected areas., PMID:26842368
Detection of risk factors for systemic adverse reactions to SCIT with natural depot allergen extracts: a retrospective study., PMID:26549339
Identification of Novel Short Ragweed Pollen Allergens Using Combined Transcriptomic and Immunoproteomic Approaches., PMID:26317427
PLD1 activation mediates Amb a 1-induced Th2-associated cytokine expression via the JNK/ATF-2 pathway in BEAS-2B cells., PMID:26302934
Pollen-derived nonallergenic substances enhance Th2-induced IgE production in B cells., PMID:26214762
Common ragweed (Ambrosia artemisiifolia L.): allergenicity and molecular characterization of pollen after plant exposure to elevated NO2., PMID:26177592
Pectate lyase pollen allergens: sensitization profiles and cross-reactivity pattern., PMID:25978036
Pollen-derived adenosine is a necessary cofactor for ragweed allergy., PMID:25939785
Identification of the cysteine protease Amb a 11 as a novel major allergen from short ragweed., PMID:25865353
Concomitant sensitization to ragweed and mugwort pollen: who is who in clinical allergy?, PMID:25053399
Immunoproteomic characterization of Ambrosia artemisiifolia pollen allergens in canine atopic dermatitis., PMID:23830203
Molecular and immunological characterization of ragweed (Ambrosia artemisiifolia L.) pollen after exposure of the plants to elevated ozone over a whole growing season., PMID:23637846
Randomized controlled trial of a ragweed allergy immunotherapy tablet in North American and European adults., PMID:23622121
IgE reactivity patterns in patients with allergic rhinoconjunctivitis to ragweed and mugwort pollens., PMID:22391077
Humoral and cellular cross-reactivity between Amb a 1, the major ragweed pollen allergen, and its mugwort homolog Art v 6., PMID:22205029
Is the strange case of mugwort sensitivity in ragweed-allergic subjects coming eventually to a solution?, PMID:21789966
Ozone affects pollen viability and NAD(P)H oxidase release from Ambrosia artemisiifolia pollen., PMID:21605929
The specific IgE reactivity pattern of weed pollen-induced allergic rhinitis patients., PMID:21189055
Multiplex microbead measurements for the characterization of cat and ragweed allergen extracts., PMID:21055660
The T-cell response to Amb a 1 is characterized by 3 dominant epitopes and multiple MHC restriction elements., PMID:20638115
A new allergen from ragweed (Ambrosia artemisiifolia) with homology to art v 1 from mugwort., PMID:20576600
Allergen-specific T cell responses to immunotherapy monitored by CD154 and intracellular cytokine expression., PMID:20412135
Local induction of a specific Th1 immune response by allergen linked immunostimulatory DNA in the nasal explants of ragweed-allergic subjects., PMID:19776676
The alpha and beta subchain of Amb a 1, the major ragweed-pollen allergen show divergent reactivity at the IgE and T-cell level., PMID:19269031
For research use only. Not for human or drug use.
