Catalog No.
YHN56101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly26-Glu123
Predicted molecular weight
13.75 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y3Q3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
C15orf22, Membrane protein p24B, p24gamma4, p26, Transmembrane emp24 domain-containing protein 3, p24 family protein gamma-4, TMED3
Transmembrane emp24 domain-containing protein 3 promotes the malignant progression of glioma by regulating the ZBTB7A signaling axis., PMID:40471367
Local cortical structure pattern and genetic links in schizophrenia: An MRI and CRISPR/Cas9 study., PMID:39862915
TMED3 promotes prostate cancer via FOXO1a and FOXO3a phosphorylation., PMID:39735675
TMED3 stabilizes SMAD2 by counteracting NEDD4-mediated ubiquitination to promote ovarian cancer., PMID:38411267
[Analyzing the evolution of insect TMED gene and the expression pattern of silkworm TMED gene]., PMID:38147997
Integrated machine learning identifies epithelial cell marker genes for improving outcomes and immunotherapy in prostate cancer., PMID:37925432
Identification of candidate genes for developmental colour agnosia in a single unique family., PMID:37672513
Genetic characterization of C. elegans TMED genes., PMID:37204056
When it doesn't run in the blood(vessels) - events involved in vascular disorders., PMID:37059363
TMED3 promotes the development of malignant melanoma by targeting CDCA8 and regulating PI3K/Akt pathway., PMID:36991473
A Genome-Wide Association Study Identified Novel Genetic Susceptibility Loci for Oral Cancer in Taiwan., PMID:36769103
Circ_0108942 Regulates the Progression of Breast Cancer by Regulating the MiR-1178-3p/TMED3 Axis., PMID:36764873
Construction of a combined random forest and artificial neural network diagnosis model to screening potential biomarker for hepatoblastoma., PMID:36271952
Analysis and Validation of TMED3 correlates with poor prognosis and tumor immune infiltration of glioma., PMID:35951089
Depleting TMED3 alleviates the development of endometrial carcinoma., PMID:35854294
TMED3 Complex Mediates ER Stress-Associated Secretion of CFTR, Pendrin, and SARS-CoV-2 Spike., PMID:35748162
Trafficking protein TMED3 promotes esophageal squamous cell carcinoma., PMID:35358714
Expression of TMED3 is independently associated with colorectal cancer prognosis., PMID:35317448
In silico analysis of microRNA genes in azoospermia factor Y-chromosome microdeletions., PMID:35124761
TMED3/RPS15A Axis promotes the development and progression of osteosarcoma., PMID:34838013
TMED3 exerts a protumor function in non-small cell lung cancer by enhancing the Wnt/β-catenin pathway via regulation of AKT., PMID:34758370
TMED3 promotes the progression and development of lung squamous cell carcinoma by regulating EZR., PMID:34429402
Long non-coding RNA RP11-283G6.5 confines breast cancer development through modulating miR-188-3p/TMED3/Wnt/β-catenin signalling., PMID:34130584
Knockdown of TMED3 inhibits cell viability and migration and increases apoptosis in human chordoma cells., PMID:33760171
TMED3 Promotes Proliferation and Migration in Breast Cancer Cells by Activating Wnt/β-Catenin Signaling., PMID:32606792
The protein secretion modulator TMED9 drives CNIH4/TGFα/GLI signaling opposing TMED3-WNT-TCF to promote colon cancer metastases., PMID:31253868
Prognostic Role of TMED3 in Clear Cell Renal Cell Carcinoma: A Retrospective Multi-Cohort Analysis., PMID:31057605
MiR-876-3p regulates cisplatin resistance and stem cell-like properties of gastric cancer cells by targeting TMED3., PMID:30843262
TMED3 promotes hepatocellular carcinoma progression via IL-11/STAT3 signaling., PMID:27901021
A novel genome-wide in vivo screen for metastatic suppressors in human colon cancer identifies the positive WNT-TCF pathway modulators TMED3 and SOX12., PMID:24920608
High-throughput transcriptomic and RNAi analysis identifies AIM1, ERGIC1, TMED3 and TPX2 as potential drug targets in prostate cancer., PMID:22761906
For research use only. Not for human or drug use.
