Catalog No.
YHC00801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly313-Ser607
Predicted molecular weight
35.99 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P02751
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cold-insoluble globulin, CIG, FN, Fibronectin, FN1
Engineered EVs-Mediated miR-222 Targeting PTEN/FN1 Axis Reverses Anthracycline Resistance in HER2-Negative Breast Cancer., PMID:40501184
Identification of adipose-proximal biomarkers in breast cancer using weighted gene co-expression network analysis., PMID:40498134
Unveiling immune and signalling proteins in recurrent pregnancy loss: GEO2R analysis sheds light., PMID:40494171
Silencing FGL1 promotes prostate cancer cell apoptosis and inhibits EMT progression., PMID:40481127
Dissecting the tumor microenvironment in primary breast angiosarcoma: insights from single-cell RNA sequencing., PMID:40474296
[Mechanistic study on low expression of Ace2 gene activated senescence-related signals and promoted the progression of silicotic fibrosis in mice]., PMID:40468507
[Mechanism of Quanduzhong Capsules in treating knee osteoarthritis from perspective of spatial heterogeneity]., PMID:40461230
LSD1 engaged ERα activation orchestrates the formation of migrasomes to promote gastric cancer metastasis., PMID:40449770
Identification of key genes regulating colorectal cancer stem cell characteristics by bioinformatics analysis., PMID:40441264
Alterations in gene expression associated with invasion of RAS-mutant thyroid tumors and their potential diagnostic and therapeutic utility., PMID:40440326
Smooth Muscle Cell-Derived Fibronectin Promotes an Atheroprotective Smooth Muscle Cell Phenotype Associated With Altered NO-cGMP Signaling., PMID:40439151
Integrin-fibronectin interaction is a pivotal biological and clinical determinant in papillary thyroid carcinoma., PMID:40423510
Ligand-Receptor Interactions Between Squamous and Endothelial Cells Induce Head and Neck Squamous Cell Carcinoma., PMID:40418639
Mechanism Analysis of Zuogui and Yougui Pills on Diabetic Nephropathy Through Transcriptional Regulatory Networks of HIF1A and PPARA., PMID:40417738
Transcriptomic characterization of the synergy between human induced pluripotent stem cells-derived liver- and pancreas-on-chip coculture., PMID:40409528
Paricalcitol plus hydroxychloroquine enhances gemcitabine activity and induces mesenchymal to epithelial transition in pancreatic ductal adenocarcinoma: A single cell RNA-seq analysis., PMID:40409452
Identification of novel gene expression patterns and pathways involved in PARP-1 inhibitor resistance., PMID:40402278
Targeting Tumor Differentiation Grade-related Genes Prognostic Signature Including COL5A1 Based on Single-cell RNA-seq in Gastric Cancer., PMID:40386054
LncRNA-5829: a novel inhibitor of cardiac fibrosis., PMID:40385274
Utilizing Stable Gene-Edited Knockout Pools for Genetic Screening and Engineering in Chinese Hamster Ovary Cells., PMID:40376717
Integrating bioinformatics and machine learning to identify glomerular injury genes and predict drug targets in diabetic nephropathy., PMID:40374840
A bioinformatics-driven approach to identify biomarkers and elucidate the pathogenesis of type 2 diabetes concurrent with pulmonary tuberculosis., PMID:40374744
Enhanced wound healing function of fibronectin variants via fusing with platelet factor 4., PMID:40373928
Multivariate chemometric design of nitric oxide-releasing chitosan nanoparticles for skin-related biomedical applications., PMID:40366133
LSM2 drives glioma progression through alternative splicing dysregulation: a multi-omics approach to identify a potential therapeutic target., PMID:40365337
A Comprehensive Analysis of Chemical Composition and Anti-Inflammatory Effects of Cassava Leaf Extracts in Two Varieties in Manihot esculenta Crantz., PMID:40362388
[Improvement effect and mechanism of Wuling San on TGF-β1-induced fibrosis, inflammation, and oxidative stress damage in HK-2 cells]., PMID:40350908
Matrix Softness Induces an Afibrogenic Lipofibroblast Phenotype in Fibroblasts from IPF Patients., PMID:40343813
Study on the role of FN1 in chronic obstructive pulmonary disease., PMID:40339769
RNA-seq analysis reveals key genes associated with downregulation of APE1 in esophageal squamous cell carcinoma., PMID:40330011
Genome-wide association study and multi-ancestry meta-analysis identify common variants associated with carotid artery intima-media thickness., PMID:40321265
Combination therapy with cetirizine and anti-PD-1 antibody suppresses colitis-induced colon tumor formation in mice., PMID:40320111
CD24, NFIL3, FN1, and KLRK1 signature predicts melanoma immunotherapy response and survival., PMID:40317346
Single-cell transcriptome unveils mesenchymal cell diversity in endometriosis., PMID:40302519
A secretome atlas of cardiac fibroblasts from healthy and infarcted mouse hearts., PMID:40301568
Modular-Based Synergetic Mechanisms of Jasminoidin and Ursodeoxycholic Acid in Cerebral Ischemia Therapy., PMID:40299522
Comprehensive profiling of candidate biomarkers and immune infiltration landscape in metabolic dysfunction-associated steatohepatitis., PMID:40292075
Network-Based Integrative Analysis to Identify Key Genes and Corresponding Reporter Biomolecules for Triple-Negative Breast Cancer., PMID:40287845
A feasibility of computational drug screening for Fuchs endothelial corneal dystrophy., PMID:40287480
Advancing pancreatic cancer therapy by mesothelin-specific nanobody conjugation., PMID:40275270
TCF4 expansion-associated loss of FN1 intron retention drives extracellular matrix accumulation in Fuchs endothelial corneal dystrophy., PMID:40268158
Fibroblast Activation Protein (FAP)+ cancer-associated fibroblasts induce macrophage M2-like polarization via the Fibronectin 1-Integrin α5β1 axis in breast cancer., PMID:40263422
Molecular characterization of suburothelial fibrosis in murine acute recurrent bladder inflammation., PMID:40258857
Proteomic profiles screening identified novel exosomal protein biomarkers for diagnosis of lung cancer., PMID:40229672
Predicting Prognosis and Immunotherapy Response in Glioblastoma (GBM) With a 5-Gene CAF-Risk Signature., PMID:40226936
Schisandrin B downregulates exosomal fibronectin 1 expression to inhibit hepatocellular carcinoma growth., PMID:40223922
Protein signatures of feed restriction and spontaneous lipolysis in ewe's skimmed milk., PMID:40221030
Targeting PRDX2 to inhibit tumor growth and metastasis in triple-negative breast cancer: the role of FN1 and the PI3K/AKT/SP1 pathway., PMID:40217291
NELL2, a novel osteoinductive factor, regulates osteoblast differentiation and bone homeostasis through fibronectin 1/integrin-mediated FAK/AKT signaling., PMID:40210857
Astragalus mongholicus bunge and Angelica sinensis botanical drug decoction mitigates lung inflammation through NOX4/TGF-β1/SMAD3 signaling., PMID:40206091
For research use only. Not for human or drug use.
