Catalog No.
YHB99101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala20-Arg218
Predicted molecular weight
25.32 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P02671
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Fibrinogen alpha chain, FGA
Proteomic Analysis of the Extracellular Matrix in the Porcine Adrenal Cortex., PMID:40493856
Neuroinflammation Markers in Tear Fluid of Mild Alzheimer's Disease., PMID:40471493
The factor V H1327R (rs1800595) polymorphism is associated with venous thromboembolic events: a case-control study in southern Iran., PMID:40464840
Bi-allelic variants in POPDC2 cause an autosomal recessive syndrome presenting with cardiac conduction defects and hypertrophic cardiomyopathy., PMID:40409267
Association of matrix metalloproteinase 7 and the alpha-chain of fibrinogen at baseline with response to methotrexate at 3 months in patients with early rheumatoid arthritis., PMID:40400044
FGA can be used as a promising therapeutic target in osteoarthritis., PMID:40394574
[Clinical characteristics and genotypes of patients with Congenital fibrinogen disorders]., PMID:40372216
HNF-1α promotes urethral fibrosis by up-regulating STAT3 transcriptional activity in mice hypospadias., PMID:40348066
Rare loss-of-function variants in HECTD2 and AKAP11 confer risk of bipolar disorder., PMID:40133559
Chronic sleep curtailment expediates brain aging by activating the complement and coagulation cascades in mice., PMID:40027811
[Molecular Pathogenic Mechanism Study of Two Cases of Inherited Dysfibrinogenemia]., PMID:40017205
Fibrinogen Alpha Chain as a Potential Serum Biomarker for Predicting Response to Cisplatin and Gemcitabine Doublet Chemotherapy in Lung Adenocarcinoma: Integrative Transcriptome and Proteome Analyses., PMID:39940778
Multiple metachronous foveolar-type gastric adenomas in a Helicobacter pylori-naïve patient with long-term use of a proton pump inhibitor: a case report., PMID:39939466
Global patterns of amyloid typing: results of a survey by the International Society of Amyloidosis (ISA)., PMID:39928315
Association of Fibrinogen Aα Thr312Ala (rs6050) Polymorphism with Venous Thrombosis and Chronic Thromboembolic Pulmonary Hypertension: A Meta-Analysis., PMID:39838925
Alternative Splicing Events and Differently Expressed Genes During Peak Mortality in Large Yellow Croaker (Larimichthys crocea) Infected with Scuticociliate., PMID:39833483
Fibrinogen genotypes and their impact on recurrence of venous thromboembolism and family history: A prospective population-based study., PMID:39828282
HN1 Functions in Protein Synthesis Regulation via mTOR-RPS6 Axis and Maintains Nucleolar Integrity., PMID:39805577
Unravelling the transcriptomic symphony of muscle ageing: key pathways and hub genes altered by ageing and caloric restriction in rat muscle revealed by RNA sequencing., PMID:39800693
Identifying the key role of mitochondrial respiration and lipid metabolism in regulating axillary osmidrosis through proteomics analysis., PMID:39673600
SARS-COV-2 ORF9b Dysregulate Fibrinogen and Albumin Genes in a Liver Cell Line., PMID:39582820
Urinary Proteomics and Systems Biology Link Eight Proteins to the Higher Risk of Hypertension and Related Complications in Blacks Versus Whites., PMID:39580674
Proteomic study of cerebrospinal fluid in adult tethered cord syndrome: Chemical structure and function of apolipoprotein B., PMID:39547612
Proteomic identification of potential biomarkers for heat tolerance in Caracu beef cattle using high and low thermotolerant groups., PMID:39538142
Transcriptomic Analysis Reveals Dynamics of Gene Expression in Liver Tissue of Spotted Sea Bass Under Acute Thermal Stress., PMID:39432208
Clinical manifestations, diagnosis and treatment of hereditary fibrinogen Aα-chain renal amyloidosis: one case report and systematic review., PMID:39417966
Identification of FGG as a Biomarker in Early Gastric Cancer via Tissue Proteomics and Clinical Verification., PMID:39417528
Deciphering Proteomic Expression in Inflammatory Disorders: A Mass Spectrometry Exploration Comparing Infectious, Noninfectious, and Traumatic Brain Injuries in Human Cerebrospinal Fluid., PMID:39391051
Genomic and clinical landscape of metastatic hormone receptors-positive breast cancers carrying ESR1 alterations., PMID:39357123
Proteomic analysis of cerebrospinal fluid of amyotrophic lateral sclerosis patients in the presence of autologous bone marrow derived mesenchymal stem cells., PMID:39278909
FGA influences invasion and metastasis of hepatocellular carcinoma through the PI3K/AKT pathway., PMID:39227068
Whole-genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles., PMID:39226462
Regulation of fibrinogen synthesis., PMID:39216273
[Clinical phenotypes and genotypes of congenital fibrinogen disorder: an analysis of 16 children]., PMID:39148389
Identification of regulatory networks and crosstalk factors in brown adipose tissue and liver of a cold-exposed cardiometabolic mouse model., PMID:39143620
Molecular Responses of Anti-VEGF Therapy in Neovascular Age-Related Macular Degeneration: Integrative Insights From Multi-Omics and Clinical Imaging., PMID:39140961
Congenital Hypodysfibrinogenemia due to γ326Cys→Tyr Mutation: Third Ever-Described Case Associated with Recurrent Venous Thrombosis and COVID Vaccine., PMID:39140696
Glycerophosphoinositol modulates FGA and NOTCH3 in exercise-induced muscle adaptation and colon cancer progression., PMID:39130639
Activated platelets retain and protect most of their factor XIII-A cargo from proteolytic activation and degradation., PMID:39116293
Genomic profiling of lymph node and distant metastases from papillary and poorly differentiated thyroid carcinomas., PMID:39030377
Discovery of candidate biomarkers from plasma-derived extracellular vesicles of patients with cirrhosis and hepatocellular carcinoma: an exploratory proteomic study., PMID:39011654
Identification of Differentially Expressed mRNAs and lncRNAs Contributes to Elucidation of Underlying Pathogenesis and Therapeutic Strategy of Recurrent Implantation Failure., PMID:38955937
Association between genetic polymorphisms in fibrinogen genes and bleeding risk in patients treated with direct oral anticoagulants., PMID:38904499
Gastric dysplastic lesions in Helicobacter pylori-naïve stomach: Foveolar-type adenoma and intestinal-type dysplasia., PMID:38837872
Skin proteomic screening and functional analysis of differential proteins associated with coat color in sheep (Ovis aries)., PMID:38754850
Systemic whole transcriptome analysis identified underlying molecular characteristics and regulatory networks implicated in the retina following optic nerve injury., PMID:38750783
Bioinformation Analysis of Differential Expression Proteins in Different Processes of COVID-19., PMID:38717820
Deciphering the similarities and disparities of molecular mechanisms behind respiratory epithelium response to HCoV-229E and SARS-CoV-2 and drug repurposing, a systems biology approach., PMID:38652363
Integration of Urinary Peptidome and Fecal Microbiome to Explore Patient Clustering in Chronic Kidney Disease., PMID:38651370
Immune system-related plasma extracellular vesicles in healthy aging., PMID:38633262
For research use only. Not for human or drug use.
