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Recombinant EV68 VP1/P1D Protein, N-His

Catalog #:   YVV41902 Specific References (50) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: Q68T42
Protein length: Ser553-Thr861
Overview

Catalog No.

YVV41902

Expression system

E. coli

Species

Human enterovirus D68 (EV68) (EV-68)

Protein length

Ser553-Thr861

Predicted molecular weight

36.32 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

Q68T42

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

Genome polyprotein, Capsid protein VP1, P1D, Virion protein 1

Data Image
  • SDS-PAGE
    SDS-PAGE for Recombinant Human enterovirus D68 (EV68) (EV-68) VP1/P1D protein
References

Sustained circulation of enterovirus D68 in Europe in 2023 and the continued evolution of enterovirus D68 B3-lineages associated with distinct amino acid substitutions in VP1 protein., PMID:40215651

A newly developed whole genome sequencing protocol enables early tracking of enterovirus D68 molecular evolution., PMID:40010645

A Novel Peptide from VP1 of EV-D68 Exhibits Broad-Spectrum Antiviral Activity Against Human Enteroviruses., PMID:39456264

VP1 is the primary determinant of neuropathogenesis in a mouse model of enterovirus D68 acute flaccid myelitis., PMID:38869283

Identification of four neutralizing antigenic sites on the enterovirus D68 capsid., PMID:38047678

Molecular epidemiology and recombination of enterovirus D68 in China., PMID:37827347

Clinical and molecular epidemiologic features of enterovirus D68 infection in children with acute lower respiratory tract infection in China., PMID:37453955

ADAR1p110 promotes Enterovirus D68 replication through its deaminase domain and inhibition of PKR pathway., PMID:36550502

Structure of Human Enterovirus 70 and Its Inhibition by Capsid-Binding Compounds., PMID:35939401

Evolution, geographic spreading, and demographic distribution of Enterovirus D68., PMID:35639811

Genetic analysis of Enterovirus D68 associated with pneumonia in children from South India., PMID:33999799

RT-nPCR Assays for Amplification and Sequencing of VP1 Genes in Human Enterovirus A-D from Clinical Specimens., PMID:33771236

Enhanced Enterovirus D68 Replication in Neuroblastoma Cells Is Associated with a Cell Culture-Adaptive Amino Acid Substitution in VP1., PMID:33148825

Mapping Attenuation Determinants in Enterovirus-D68., PMID:32784424

Pharmacological Characterization of the Mechanism of Action of R523062, a Promising Antiviral for Enterovirus D68., PMID:32692536

A decade of enterovirus genetic diversity in Belgium., PMID:31722268

A Novel Capsid Binding Inhibitor Displays Potent Antiviral Activity against Enterovirus D68., PMID:31532189

Epidemiologic and Molecular Study of EVs in Hospitalized Children With Severe Acute Respiratory Infection., PMID:31469780

Upsurge of Enterovirus D68 and Circulation of the New Subclade D3 and Subclade B3 in Beijing, China, 2016., PMID:30988475

Molecular basis for the acid-initiated uncoating of human enterovirus D68., PMID:30530701

Surveillance of enteroviruses from paediatric patients attended at a tertiary hospital in Catalonia from 2014 to 2017., PMID:30530096

Contemporary Circulating Enterovirus D68 Strains Have Acquired the Capacity for Viral Entry and Replication in Human Neuronal Cells., PMID:30327438

A Novel Neutralizing Antibody Specific to the DE Loop of VP1 Can Inhibit EV-D68 Infection in Mice., PMID:30282753

Recommendations for enterovirus diagnostics and characterisation within and beyond Europe., PMID:29414181

Enterovirus-D68 (EV-D68) in pediatric patients with respiratory infection: The circulation of a new B3 clade in Italy., PMID:29396353

A virus-like particle vaccine confers protection against enterovirus D68 lethal challenge in mice., PMID:29295756

Enterovirus D68-Associated Acute Flaccid Myelitis in Immunocompromised Woman, Italy., PMID:28930024

Distinct genetic clades of enterovirus D68 detected in 2010, 2013, and 2015 in Osaka City, Japan., PMID:28902862

Enterovirus genotypes among patients with severe acute respiratory illness, influenza-like illness, and asymptomatic individuals in South Africa, 2012-2014., PMID:28574589

First Report of a Fatal Case Associated with EV-D68 Infection in Hong Kong and Emergence of an Interclade Recombinant in China Revealed by Genome Analysis., PMID:28509856

Nasal Infection of Enterovirus D68 Leading to Lower Respiratory Tract Pathogenesis in Ferrets (Mustela putorius furo)., PMID:28489053

Detection of enterovirus D68 in patients hospitalised in three tertiary university hospitals in Germany, 2013 to 2014., PMID:27195917

Epidemiological and clinical characteristics of patients infected with enterovirus D68, France, July to December 2014., PMID:27195770

Respiratory infections associated with enterovirus D68 from 2011 to 2015 in Beijing, China., PMID:26896830

Respiratory Infections by Enterovirus D68 in Outpatients and Inpatients Spanish Children., PMID:26741582

Molecular Evolution and Intraclade Recombination of Enterovirus D68 during the 2014 Outbreak in the United States., PMID:26656685

Full genome analysis of enterovirus D-68 strains circulating in Alberta, Canada., PMID:26643129

Analysis of Enterovirus 68 Strains from the 2014 North American Outbreak Reveals a New Clade, Indicating Viral Evolution., PMID:26630383

Molecular and epidemiological study of enterovirus D68 in Taiwan., PMID:26458357

Antiviral Activity of Broad-Spectrum and Enterovirus-Specific Inhibitors against Clinical Isolates of Enterovirus D68., PMID:26369972

European surveillance for enterovirus D68 during the emerging North-American outbreak in 2014., PMID:26364237

First Enterovirus D68 (EV-D68) cases detected in hospitalised patients in a tertiary care university hospital in Spain, October 2014., PMID:25735714

Cell surface nucleolin facilitates enterovirus 71 binding and infection., PMID:25673703

Genetic diversity of human enterovirus 68 strains isolated in Kenya using the hypervariable 3'-end of VP1 gene., PMID:25054861

Molecular evolution of enterovirus 68 detected in the Philippines., PMID:24073203

A peptide vaccine based on a B-cell epitope on the VP1 protein of enterovirus 70 induces a strong antibody response., PMID:23237090

Molecular epidemiology and evolution of human enterovirus serotype 68 in Thailand, 2006-2011., PMID:22586446

Lineages, sub-lineages and variants of enterovirus 68 in recent outbreaks., PMID:22536453

Upsurge of human enterovirus 68 infections in patients with severe respiratory tract infections., PMID:21802981

Molecular typing and epidemiology of non-polio enteroviruses isolated from Yunnan Province, the People's Republic of China., PMID:18297723

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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Recombinant EV68 VP1/P1D Protein, N-His [YVV41902]
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