Catalog No.
YVV41902
Expression system
E. coli
Species
Human enterovirus D68 (EV68) (EV-68)
Protein length
Ser553-Thr861
Predicted molecular weight
36.32 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q68T42
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Genome polyprotein, Capsid protein VP1, P1D, Virion protein 1
Sustained circulation of enterovirus D68 in Europe in 2023 and the continued evolution of enterovirus D68 B3-lineages associated with distinct amino acid substitutions in VP1 protein., PMID:40215651
A newly developed whole genome sequencing protocol enables early tracking of enterovirus D68 molecular evolution., PMID:40010645
A Novel Peptide from VP1 of EV-D68 Exhibits Broad-Spectrum Antiviral Activity Against Human Enteroviruses., PMID:39456264
VP1 is the primary determinant of neuropathogenesis in a mouse model of enterovirus D68 acute flaccid myelitis., PMID:38869283
Identification of four neutralizing antigenic sites on the enterovirus D68 capsid., PMID:38047678
Molecular epidemiology and recombination of enterovirus D68 in China., PMID:37827347
Clinical and molecular epidemiologic features of enterovirus D68 infection in children with acute lower respiratory tract infection in China., PMID:37453955
ADAR1p110 promotes Enterovirus D68 replication through its deaminase domain and inhibition of PKR pathway., PMID:36550502
Structure of Human Enterovirus 70 and Its Inhibition by Capsid-Binding Compounds., PMID:35939401
Evolution, geographic spreading, and demographic distribution of Enterovirus D68., PMID:35639811
Genetic analysis of Enterovirus D68 associated with pneumonia in children from South India., PMID:33999799
RT-nPCR Assays for Amplification and Sequencing of VP1 Genes in Human Enterovirus A-D from Clinical Specimens., PMID:33771236
Enhanced Enterovirus D68 Replication in Neuroblastoma Cells Is Associated with a Cell Culture-Adaptive Amino Acid Substitution in VP1., PMID:33148825
Mapping Attenuation Determinants in Enterovirus-D68., PMID:32784424
Pharmacological Characterization of the Mechanism of Action of R523062, a Promising Antiviral for Enterovirus D68., PMID:32692536
A decade of enterovirus genetic diversity in Belgium., PMID:31722268
A Novel Capsid Binding Inhibitor Displays Potent Antiviral Activity against Enterovirus D68., PMID:31532189
Epidemiologic and Molecular Study of EVs in Hospitalized Children With Severe Acute Respiratory Infection., PMID:31469780
Upsurge of Enterovirus D68 and Circulation of the New Subclade D3 and Subclade B3 in Beijing, China, 2016., PMID:30988475
Molecular basis for the acid-initiated uncoating of human enterovirus D68., PMID:30530701
Surveillance of enteroviruses from paediatric patients attended at a tertiary hospital in Catalonia from 2014 to 2017., PMID:30530096
Contemporary Circulating Enterovirus D68 Strains Have Acquired the Capacity for Viral Entry and Replication in Human Neuronal Cells., PMID:30327438
A Novel Neutralizing Antibody Specific to the DE Loop of VP1 Can Inhibit EV-D68 Infection in Mice., PMID:30282753
Recommendations for enterovirus diagnostics and characterisation within and beyond Europe., PMID:29414181
Enterovirus-D68 (EV-D68) in pediatric patients with respiratory infection: The circulation of a new B3 clade in Italy., PMID:29396353
A virus-like particle vaccine confers protection against enterovirus D68 lethal challenge in mice., PMID:29295756
Enterovirus D68-Associated Acute Flaccid Myelitis in Immunocompromised Woman, Italy., PMID:28930024
Distinct genetic clades of enterovirus D68 detected in 2010, 2013, and 2015 in Osaka City, Japan., PMID:28902862
Enterovirus genotypes among patients with severe acute respiratory illness, influenza-like illness, and asymptomatic individuals in South Africa, 2012-2014., PMID:28574589
First Report of a Fatal Case Associated with EV-D68 Infection in Hong Kong and Emergence of an Interclade Recombinant in China Revealed by Genome Analysis., PMID:28509856
Nasal Infection of Enterovirus D68 Leading to Lower Respiratory Tract Pathogenesis in Ferrets (Mustela putorius furo)., PMID:28489053
Detection of enterovirus D68 in patients hospitalised in three tertiary university hospitals in Germany, 2013 to 2014., PMID:27195917
Epidemiological and clinical characteristics of patients infected with enterovirus D68, France, July to December 2014., PMID:27195770
Respiratory infections associated with enterovirus D68 from 2011 to 2015 in Beijing, China., PMID:26896830
Respiratory Infections by Enterovirus D68 in Outpatients and Inpatients Spanish Children., PMID:26741582
Molecular Evolution and Intraclade Recombination of Enterovirus D68 during the 2014 Outbreak in the United States., PMID:26656685
Full genome analysis of enterovirus D-68 strains circulating in Alberta, Canada., PMID:26643129
Analysis of Enterovirus 68 Strains from the 2014 North American Outbreak Reveals a New Clade, Indicating Viral Evolution., PMID:26630383
Molecular and epidemiological study of enterovirus D68 in Taiwan., PMID:26458357
Antiviral Activity of Broad-Spectrum and Enterovirus-Specific Inhibitors against Clinical Isolates of Enterovirus D68., PMID:26369972
European surveillance for enterovirus D68 during the emerging North-American outbreak in 2014., PMID:26364237
First Enterovirus D68 (EV-D68) cases detected in hospitalised patients in a tertiary care university hospital in Spain, October 2014., PMID:25735714
Cell surface nucleolin facilitates enterovirus 71 binding and infection., PMID:25673703
Genetic diversity of human enterovirus 68 strains isolated in Kenya using the hypervariable 3'-end of VP1 gene., PMID:25054861
Molecular evolution of enterovirus 68 detected in the Philippines., PMID:24073203
A peptide vaccine based on a B-cell epitope on the VP1 protein of enterovirus 70 induces a strong antibody response., PMID:23237090
Molecular epidemiology and evolution of human enterovirus serotype 68 in Thailand, 2006-2011., PMID:22586446
Lineages, sub-lineages and variants of enterovirus 68 in recent outbreaks., PMID:22536453
Upsurge of human enterovirus 68 infections in patients with severe respiratory tract infections., PMID:21802981
Molecular typing and epidemiology of non-polio enteroviruses isolated from Yunnan Province, the People's Republic of China., PMID:18297723
For research use only. Not for human or drug use.
