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Anti-CD77 Antibody (5B5), PerCp

Catalog #:   FGN55624 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: FCM
Overview

Catalog No.

FGN55624

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Conjugation

PerCp

Target

CD77, globotriaosylcermamide (Gb3), Burkitt's lymphoma associated antigen (BLA), cermadie trihexoside (CTH), and Pk blood group antigen

Endotoxin level

Please contact with the lab for this information.

Purification

Affinity chromatography.

Applications

FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Stability and Storage

Store at 4°C for 12 months. Protect from light. Do not freeze.

Clone ID

5B5

Data Image
References

Repurposing the Pentameric B-Subunit of Shiga Toxin for Gb3-Targeted Immunotherapy of Colorectal Cancer by Rhamnose Conjugation., PMID:35905973

Shiga Toxins: An Update on Host Factors and Biomedical Applications., PMID:33803852

The interaction between flagellin and the glycosphingolipid Gb3 on host cells contributes to Bacillus cereus acute infection., PMID:32507026

Verotoxin Receptor-Based Pathology and Therapies., PMID:32296648

Detection of blood Gb3 deposits as a new tool for diagnosis and therapy monitoring in patients with classic Fabry disease., PMID:29974530

Single nucleotide polymorphisms in A4GALT spur extra products of the human Gb3/CD77 synthase and underlie the P1PK blood group system., PMID:29709005

Intracellular drug delivery: Potential usefulness of engineered Shiga toxin subunit B for targeted cancer therapy., PMID:29432805

Cell surface markers for the identification and study of human naive pluripotent stem cells., PMID:29227830

Streptococcal Adhesin P (SadP) contributes to Streptococcus suis adhesion to the human intestinal epithelium., PMID:28407026

Skin Globotriaosylceramide 3 Load Is Increased in Men with Advanced Fabry Disease., PMID:27851774

Immunization of A4galt-deficient mice with glycosphingolipids from renal cell cancers resulted in the generation of anti-sulfoglycolipid monoclonal antibodies., PMID:26883028

Gastric Adenocarcinomas Express the Glycosphingolipid Gb3/CD77: Targeting of Gastric Cancer Cells with Shiga Toxin B-Subunit., PMID:26826119

Evaluation of biological safety in vitro and immunogenicity in vivo of recombinant Escherichia coli Shiga toxoids as candidate vaccines in cattle., PMID:25889651

Direct acute tubular damage contributes to Shigatoxin-mediated kidney failure., PMID:24909663

An innovative method to identify autoantigens expressed on the endothelial cell surface: serological identification system for autoantigens using a retroviral vector and flow cytometry (SARF)., PMID:23401699

A single point mutation in the gene encoding Gb3/CD77 synthase causes a rare inherited polyagglutination syndrome., PMID:22965229

Establishment of recombinant hybrid-IgG/IgA immunoglobulin specific for Shiga toxin., PMID:21883352

Quantitative transcriptomic profiling of branching in a glycosphingolipid biosynthetic pathway., PMID:21665948

Efficient generation of useful monoclonal antibodies reactive with globotriaosylceramide using knockout mice lacking Gb3/CD77 synthase., PMID:21660412

Targeted urine microscopy in Anderson-Fabry disease: a cheap, sensitive and specific diagnostic technique., PMID:21382994

On the structural diversity of Shiga toxin glycosphingolipid receptors in lymphoid and myeloid cells determined by nanoelectrospray ionization tandem mass spectrometry., PMID:20623712

A synthetic globotriaosylceramide analogue inhibits HIV-1 infection in vitro by two mechanisms., PMID:20582467

IL-21 and IL-10 have redundant roles but differential capacities at different stages of Plasma Cell generation from human Germinal Center B cells., PMID:19762555

CXCR4 expression functionally discriminates centroblasts versus centrocytes within human germinal center B cells., PMID:19494283

Shiga toxins, glycosphingolipid diversity, and endothelial cell injury., PMID:19190807

Epithelial and mesenchymal cells in the bovine colonic mucosa differ in their responsiveness to Escherichia coli Shiga toxin 1., PMID:18765725

Structural basis of the preferential binding for globo-series glycosphingolipids displayed by Pseudomonas aeruginosa lectin I., PMID:18762193

Glycosphingolipids in vascular endothelial cells: relationship of heterogeneity in Gb3Cer/CD77 receptor expression with differential Shiga toxin 1 cytotoxicity., PMID:18176841

CD45RO enriches for activated, highly mutated human germinal center B cells., PMID:17644737

CD45RO: a marker for BCR-mediated selection., PMID:17635802

Dynamic interplay between the neutral glycosphingolipid CD77/Gb3 and the therapeutic antibody target CD20 within the lipid bilayer of model B lymphoma cells., PMID:17336267

Ligation of centrocyte/centroblast marker 1 on Epstein-Barr virus--transformed B lymphocytes induces cell death in a reactive oxygen species--dependent manner., PMID:17055356

Toll-like receptor 2-mediated human B cell differentiation., PMID:16766226

Targeted disruption of Gb3/CD77 synthase gene resulted in the complete deletion of globo-series glycosphingolipids and loss of sensitivity to verotoxins., PMID:16476743

Application of combined high-performance thin-layer chromatography immunostaining and nanoelectrospray ionization quadrupole time-of-flight tandem mass spectrometry to the structural characterization of high- and low-affinity binding ligands of Shiga toxin 1., PMID:16285017

A comparison of Verotoxin B-subunit (Stx1B) and CD77 antibody to define germinal centre populations., PMID:16165112

Transformation of BCR-deficient germinal-center B cells by EBV supports a major role of the virus in the pathogenesis of Hodgkin and posttransplantation lymphomas., PMID:16131568

Human tonsil implants xenotransplanted in SCID mice display broad lymphocytic diversity and cellular activation profile similar to those in the original lymphoid organ., PMID:15598272

Recapitulation of B cell differentiation in the central nervous system of patients with multiple sclerosis., PMID:15263096

Adult T-cell leukemia/lymphoma (ATLL): report of two fully documented Hellenic patients., PMID:15160945

Identification of germinal center B cells in blood from HIV-infected drug-naive individuals in Central Africa., PMID:15154608

The blood group P1 synthase gene is identical to the Gb3/CD77 synthase gene. A clue to the solution of the P1/P2/p puzzle., PMID:12888565

Gene expression dynamics during germinal center transit in B cells., PMID:12727636

Bovine lymphocytes express functional receptors for Escherichia coli Shiga toxin 1., PMID:12495672

CD40 ligation downregulates EBNA-2 and LMP-1 expression in EBV-transformed lymphoblastoid cell lines., PMID:12115504

Comparison of adhesion mechanisms and surface protein expression in CD77-positive and CD77-negative Burkitt's lymphoma cells., PMID:11838967

Bm1-Bm5 classification of peripheral blood B cells reveals circulating germinal center founder cells in healthy individuals and disturbance in the B cell subpopulations in patients with primary Sjögren's syndrome., PMID:11564773

Interaction of cytokines and growth factor in the regulation of verotoxin-induced apoptosis in cultured human endothelial cells., PMID:11442480

The liver flukes Fasciola gigantica and Fasciola hepatica express the leucocyte cluster of differentiation marker CD77 (globotriaosylceramide) in their tegument., PMID:11308018

Inhibition of Vero cell cytotoxic activity in Escherichia coli O157:H7 lysates by globotriaosylceramide, Gb3, from bovine milk., PMID:11302178

Datasheet
$ 270
Product specifications
50 T 270 100 T 446

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Anti-CD77 Antibody (5B5), PerCp [FGN55624]
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