Repurposing the Pentameric B-Subunit of Shiga Toxin for Gb3-Targeted Immunotherapy of Colorectal Cancer by Rhamnose Conjugation., PMID:35905973
Shiga Toxins: An Update on Host Factors and Biomedical Applications., PMID:33803852
The interaction between flagellin and the glycosphingolipid Gb3 on host cells contributes to Bacillus cereus acute infection., PMID:32507026
Verotoxin Receptor-Based Pathology and Therapies., PMID:32296648
Detection of blood Gb3 deposits as a new tool for diagnosis and therapy monitoring in patients with classic Fabry disease., PMID:29974530
Single nucleotide polymorphisms in A4GALT spur extra products of the human Gb3/CD77 synthase and underlie the P1PK blood group system., PMID:29709005
Intracellular drug delivery: Potential usefulness of engineered Shiga toxin subunit B for targeted cancer therapy., PMID:29432805
Cell surface markers for the identification and study of human naive pluripotent stem cells., PMID:29227830
Streptococcal Adhesin P (SadP) contributes to Streptococcus suis adhesion to the human intestinal epithelium., PMID:28407026
Skin Globotriaosylceramide 3 Load Is Increased in Men with Advanced Fabry Disease., PMID:27851774
Immunization of A4galt-deficient mice with glycosphingolipids from renal cell cancers resulted in the generation of anti-sulfoglycolipid monoclonal antibodies., PMID:26883028
Gastric Adenocarcinomas Express the Glycosphingolipid Gb3/CD77: Targeting of Gastric Cancer Cells with Shiga Toxin B-Subunit., PMID:26826119
Evaluation of biological safety in vitro and immunogenicity in vivo of recombinant Escherichia coli Shiga toxoids as candidate vaccines in cattle., PMID:25889651
Direct acute tubular damage contributes to Shigatoxin-mediated kidney failure., PMID:24909663
An innovative method to identify autoantigens expressed on the endothelial cell surface: serological identification system for autoantigens using a retroviral vector and flow cytometry (SARF)., PMID:23401699
A single point mutation in the gene encoding Gb3/CD77 synthase causes a rare inherited polyagglutination syndrome., PMID:22965229
Establishment of recombinant hybrid-IgG/IgA immunoglobulin specific for Shiga toxin., PMID:21883352
Quantitative transcriptomic profiling of branching in a glycosphingolipid biosynthetic pathway., PMID:21665948
Efficient generation of useful monoclonal antibodies reactive with globotriaosylceramide using knockout mice lacking Gb3/CD77 synthase., PMID:21660412
Targeted urine microscopy in Anderson-Fabry disease: a cheap, sensitive and specific diagnostic technique., PMID:21382994
On the structural diversity of Shiga toxin glycosphingolipid receptors in lymphoid and myeloid cells determined by nanoelectrospray ionization tandem mass spectrometry., PMID:20623712
A synthetic globotriaosylceramide analogue inhibits HIV-1 infection in vitro by two mechanisms., PMID:20582467
IL-21 and IL-10 have redundant roles but differential capacities at different stages of Plasma Cell generation from human Germinal Center B cells., PMID:19762555
CXCR4 expression functionally discriminates centroblasts versus centrocytes within human germinal center B cells., PMID:19494283
Shiga toxins, glycosphingolipid diversity, and endothelial cell injury., PMID:19190807
Epithelial and mesenchymal cells in the bovine colonic mucosa differ in their responsiveness to Escherichia coli Shiga toxin 1., PMID:18765725
Structural basis of the preferential binding for globo-series glycosphingolipids displayed by Pseudomonas aeruginosa lectin I., PMID:18762193
Glycosphingolipids in vascular endothelial cells: relationship of heterogeneity in Gb3Cer/CD77 receptor expression with differential Shiga toxin 1 cytotoxicity., PMID:18176841
CD45RO enriches for activated, highly mutated human germinal center B cells., PMID:17644737
CD45RO: a marker for BCR-mediated selection., PMID:17635802
Dynamic interplay between the neutral glycosphingolipid CD77/Gb3 and the therapeutic antibody target CD20 within the lipid bilayer of model B lymphoma cells., PMID:17336267
Ligation of centrocyte/centroblast marker 1 on Epstein-Barr virus--transformed B lymphocytes induces cell death in a reactive oxygen species--dependent manner., PMID:17055356
Toll-like receptor 2-mediated human B cell differentiation., PMID:16766226
Targeted disruption of Gb3/CD77 synthase gene resulted in the complete deletion of globo-series glycosphingolipids and loss of sensitivity to verotoxins., PMID:16476743
Application of combined high-performance thin-layer chromatography immunostaining and nanoelectrospray ionization quadrupole time-of-flight tandem mass spectrometry to the structural characterization of high- and low-affinity binding ligands of Shiga toxin 1., PMID:16285017
A comparison of Verotoxin B-subunit (Stx1B) and CD77 antibody to define germinal centre populations., PMID:16165112
Transformation of BCR-deficient germinal-center B cells by EBV supports a major role of the virus in the pathogenesis of Hodgkin and posttransplantation lymphomas., PMID:16131568
Human tonsil implants xenotransplanted in SCID mice display broad lymphocytic diversity and cellular activation profile similar to those in the original lymphoid organ., PMID:15598272
Recapitulation of B cell differentiation in the central nervous system of patients with multiple sclerosis., PMID:15263096
Adult T-cell leukemia/lymphoma (ATLL): report of two fully documented Hellenic patients., PMID:15160945
Identification of germinal center B cells in blood from HIV-infected drug-naive individuals in Central Africa., PMID:15154608
The blood group P1 synthase gene is identical to the Gb3/CD77 synthase gene. A clue to the solution of the P1/P2/p puzzle., PMID:12888565
Gene expression dynamics during germinal center transit in B cells., PMID:12727636
Bovine lymphocytes express functional receptors for Escherichia coli Shiga toxin 1., PMID:12495672
CD40 ligation downregulates EBNA-2 and LMP-1 expression in EBV-transformed lymphoblastoid cell lines., PMID:12115504
Comparison of adhesion mechanisms and surface protein expression in CD77-positive and CD77-negative Burkitt's lymphoma cells., PMID:11838967
Bm1-Bm5 classification of peripheral blood B cells reveals circulating germinal center founder cells in healthy individuals and disturbance in the B cell subpopulations in patients with primary Sjögren's syndrome., PMID:11564773
Interaction of cytokines and growth factor in the regulation of verotoxin-induced apoptosis in cultured human endothelial cells., PMID:11442480
The liver flukes Fasciola gigantica and Fasciola hepatica express the leucocyte cluster of differentiation marker CD77 (globotriaosylceramide) in their tegument., PMID:11308018
Inhibition of Vero cell cytotoxic activity in Escherichia coli O157:H7 lysates by globotriaosylceramide, Gb3, from bovine milk., PMID:11302178
For research use only. Not for human or drug use.
