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InVivoMAb Anti-Mouse EGFR & CD3e Bispecific Antibody (Iv0272)

Catalog #:   VMB86901 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG
Applications: FuncS
Accession: Q01279 & P22646
Overview

Catalog No.

VMB86901

Species reactivity

Mouse

Host species

Mouse

Isotype

IgG

Clonality

Monoclonal

Target

Bispecific, Epidermal growth factor receptor, 2.7.10.1, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, EGFR, ERBB, ERBB1, HER1, T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, Cd3e

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q01279 & P22646

Applications

FuncS

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

Iv0272

Data Image
References

Kidney function is associated with plasma ATN biomarkers among Hispanics/Latinos: SOL-INCA and HCHS/SOL results., PMID:40537838

Identifying pathways to cardiovascular mortality by causal graphical models and mediation analysis among hypertensive patients: insights from a prospective study., PMID:40537785

Recommendations for diagnosis and management of non-small-cell lung carcinoma patients with ex20ins EGFR mutations: insights from a Delphi consensus., PMID:40537728

Osimertinib Dose Optimization Guided by Therapeutic Drug Monitoring in Patients With EGFR-Mutated Advanced Non-Small Cell Lung Cancer: A Case series., PMID:40537319

Use, Usability, and Experience Testing of a Digital Health Intervention to Support Chronic Kidney Disease Self-Management: Mixed Methods Study., PMID:40537087

Exploring the Interactions between Drugs and Metabolic Disturbances in CKD: An Example with Oral Anticoagulants., PMID:40536820

Effects of SGLT2 Inhibitors on Lower eGFR Decline in Non-Diabetic CKD Patients without Proteinuria., PMID:40536807

It's a match: use of the radionuclide theranostic pair 133La/225Ac for the radiopharmacological characterization of EGFR-targeted single-domain antibodies., PMID:40536585

RETRACTED: Erira et al. Differential Regulation of the EGFR/PI3K/AKT/PTEN Pathway between Low- and High-Grade Gliomas. Brain Sci. 2021, 11, 1655., PMID:40536529

Corrigendum to "TP53 and EGFR amplification are negative predictors of overall survival in patients diagnosed with non-small cell lung cancer with brain metastases" [Heliyon Volume 10, Issue 16, August 2024, Article e36532]., PMID:40535885

High MIG-6 expression promotes tumor proliferation and metastasis of gastric cancer., PMID:40535815

Development of Traditional Chinese Medicine in combination with EGFR Inhibitors against Cancer., PMID:40535810

Ramucirumab and erlotinib combination as first-line treatment for advanced or recurrent non-small cell lung cancer harboring EGFR Exon21 L858R mutation: a multicenter retrospective observational cohort study in Japan (REAL-SPEED)., PMID:40535732

Nonlinear Associations Between Kidney Function Markers and Body Mass Index Among Women of Reproductive Age in Bangladesh., PMID:40535386

Aumolertinib plus bevacizumab for untreated advanced NSCLC with EGFR sensitive mutation., PMID:40535140

Deep learning in histopathology images for prediction of oncogenic driver molecular alterations in lung cancer: a systematic review and meta-analysis., PMID:40535093

Comparative effectiveness of pembrolizumab-chemotherapy versus chemotherapy with/without bevacizumab in unresectable, locally advanced or metastatic non-small cell lung cancer: a Chinese multicenter real-world analysis emphasizing PD-L1-negative populations., PMID:40535092

Ivonescimab plus chemotherapy in advanced or metastatic non‑squamous non‑small cell lung cancer with EGFR variant in China: a cost-effectiveness analysis., PMID:40535084

Clinicopathological factors vs. molecular model for predicting adjuvant EGFR-TKI benefit in stage I EGFR-mutant non-small cell lung cancer., PMID:40535079

Impacts of co-mutations in oligometastatic and oligoprogressive non-small cell lung cancer with EGFR/ALK mutations-a narrative review of the current literature., PMID:40535066

Combination of immune checkpoint inhibitors with multi-targeted tyrosine kinase inhibitors for second- or later-line therapy of non-small cell lung cancer: a systematic review and meta-analysis., PMID:40535065

Epidermal Growth Factor Receptor Kinase Domain Duplication in Lung Adenocarcinoma with Response to Osimertinib: A Case Report and Literature Review., PMID:40534731

[Comparison of the efficacy, safety, and cost-effectiveness of trastuzumab biosimilar HLX02 and the originator combined with pertuzumab and chemotherapy in the neoadjuvant treatment of patients with HER-2-positive breast cancer]., PMID:40534267

PI3K-dependent GAB1/Erk phosphorylation renders head and neck squamous cell carcinoma sensitive to PI3Kα inhibitors., PMID:40533463

N6-methyladenosine-modified GPX2 impacts cancer cell stemness and TKI resistance through regulating of redox metabolism., PMID:40533443

"Partial Nephrectomy with Veriset: A Renorrhaphy-Less Approach"., PMID:40533087

Effects of Ganoderma spent substrate containing with polysaccharides and triterpenoids on the growth performance, antioxidant capacity and immunity level of chickens., PMID:40532998

Identifying the genomic landscape of EGFR-mutant lung cancers with CNS metastases., PMID:40532851

SGLT-2 inhibitors: a deeper dive into their renal protective properties beyond glycemic control and proteinuria reduction., PMID:40532669

Safety and efficacy of perioperative dual PD-1 and HER2 blockade in HER2-positive gastric cancer., PMID:40532664

Metabolic control of glycosylation forms for establishing glycan-dependent protein interaction networks., PMID:40531880

Design, synthesis and anti-tumor activity of oleanolic acid derivatives targeting EGFR., PMID:40531475

Local cranial radiation combined with third-generation tyrosine kinase inhibitors improve leptomeningeal metastasis disease-free survival in patients with EGFR-mutated non-small cell lung cancer and brain metastasis., PMID:40531436

HEY1 promotes the development and metastasis of osteosarcoma through CD44/EGFR/FAK pathway., PMID:40531089

PD-1/PD-L1 inhibitors plus chemotherapy versus chemotherapy alone for TKIs-resistant, EGFR-Mutant, advanced non-small-cell lung cancer: a phase 3 RCTs based meta-analysis., PMID:40531080

TRPV3 calcium channel at the crossroads of epidermal differentiation and inflammation., PMID:40530577

Karyomegalic interstitial nephritis: A case series and review of the literature on genetic insights and clinical challenges., PMID:40529986

Integrated pan-cancer analysis of ADM's role in prognosis, immune modulation and resistance., PMID:40529377

Angio-associated migratory cell protein promotes colorectal cancer progression by enhancing phosphoglycerate kinase 1 phosphorylation., PMID:40529105

From planning to prognosis: predicting renal function after minimally-invasive partial nephrectomy with artificial intelligence., PMID:40528776

Growth Inhibition Activity Assessment of γ-Lactam-Containing Chemicals in Cultured MCF-7 Cells and Xenografted Chick Embryos., PMID:40528652

Real-World Survival Outcomes of Patients With High PD-L1 Advanced NSCLC Who Received Chemoimmunotherapy Versus Immunotherapy., PMID:40528544

EGFR-TKI combination treatment for NSCLC with EGFR-sensitive mutation., PMID:40528340

Impact of Bariatric Metabolic Surgery on Cardiovascular, Kidney, and Mortality Outcomes Among Adults with Obesity and Chronic Kidney Disease Across Different Time Frames., PMID:40528074

Clinicopathological features and renal outcomes in patients with IgA nephropathy secondary to psoriasis., PMID:40528031

EGFRvIII-positive glioblastoma contributes to immune escape and malignant progression via the c-Fos-MDK-LRP1 axis., PMID:40527884

Prevalence and characteristics of lung cancer in families harboring Pathogenic Germline Variants in cancer predisposing genes: A 20-year retrospective analysis., PMID:40527197

Immune Subtyping Identifies Patients With Hormone Receptor-Positive Early-Stage Breast Cancer Who Respond to Neoadjuvant Immunotherapy (IO): Results From Five IO Arms of the I-SPY2 Trial., PMID:40526879

Amphiregulin contributes to neuropathic pain by enhancing glycolysis that stimulates histone lactylation in sensory neurons., PMID:40526786

Multitarget inhibition of CDK2, EGFR, and tubulin by phenylindole derivatives: Insights from 3D-QSAR, molecular docking, and dynamics for cancer therapy., PMID:40526618

Datasheet
$ 484
Product specifications
100 μg 484 1 mg 1932

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For research use only. Not for human or drug use.

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InVivoMAb Anti-Mouse EGFR & CD3e Bispecific Antibody (Iv0272) [VMB86901]
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