Catalog No.
EHK07302
Expression system
Insect Cells
Species
Homo sapiens (Human)
Protein length
Phe29-Ser455
Predicted molecular weight
50.51 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UIR0
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
BTNL2, Butyrophilin-like protein 2, BTL-II
Genetic Polymorphisms of Immunity Regulatory Genes and Alopecia Areata Susceptibility in Jordanian Patients., PMID:39459398
Schizophrenia and Rheumatoid Arthritis Genetic Scenery: Potential Non-HLA Genes Involved in Both Diseases Relationship., PMID:39351328
Clinical Patterns of Sarcoidosis Patients with and without Uveitis: Insights from a Dutch Sarcoidosis Centre., PMID:38916581
Shared genetic factors and causal association between chronic hepatitis C infection and diffuse large B cell lymphoma., PMID:38654358
The B7:CD28 family and friends: Unraveling coinhibitory interactions., PMID:38354702
N-terminal ectodomain of BTNL2 inhibits T cell activation via a non-canonical interaction with its putative receptor that results in a delayed progression of DSS-induced ulcerative colitis., PMID:38219401
Impact of missense TSBP1 variants on the susceptibility to coronary heart disease., PMID:38042215
[A comparison of DNA methylation profiles of blood mononuclear cells in patients with multiple sclerosis in remission and relapse]., PMID:37560835
Construction and validation of stemness-related lncRNA pair signature for predicting prognosis in colorectal cancer., PMID:37410143
A human leukocyte antigen imputation study uncovers possible genetic interplay between gut inflammatory processes and autism spectrum disorders., PMID:37407551
Epigenome-wide association study identifies Vogt-Koyanagi-Harada disease-associated DNA methylation loci in Chinese., PMID:37394087
Germline variants of the genes involved in NF-kB activation are associated with the risk of COPD and lung cancer development., PMID:37307368
Construction of an oxidative stress-related lncRNAs signature to predict prognosis and the immune response in gastric cancer., PMID:37258567
BTNL2 promotes colitis-associated tumorigenesis in mice by regulating IL-22 production., PMID:36629012
Validation of SNP markers for thermotolerance adaptation in Ovis aries adapted to different climatic regions using KASP-PCR technique., PMID:36572697
Exome variants associated with asthma and allergy., PMID:36470944
BCHE as a Prognostic Biomarker in Endometrial Cancer and Its Correlation with Immunity., PMID:35915658
Experimental Study of Potential CD8+ Trivalent Synthetic Peptides for Liver Cancer Vaccine Development Using Sprague Dawley Rat Models., PMID:35686237
DNA sequencing validation by PCR-RFLP for evaluating butyrophilin-like 2 rs2076530 polymorphism in Iranian patients with sarcoidosis., PMID:35115755
Cancer cell-expressed BTNL2 facilitates tumour immune escape via engagement with IL-17A-producing γδ T cells., PMID:35017553
An updated view of the pathogenesis of steroid-sensitive nephrotic syndrome., PMID:35006356
Genome-wide association study identifies BTNL2 associated with atopic asthma in children., PMID:34871226
Multi-omics analysis of the expression and prognostic value of the butyrophilins in breast cancer., PMID:34411352
Butyrophilin-like 2 regulates site-specific adaptations of intestinal γδ intraepithelial lymphocytes., PMID:34312491
Genetic Variation and Cardiovascular Risk Factors: A Cohort Study on Migrants from the Former Soviet Union and a Native German Population., PMID:34201265
Analysis of single nucleotide polymorphisms in chronic beryllium disease., PMID:33863318
The Regulatory Cross-Talk between microRNAs and Novel Members of the B7 Family in Human Diseases: A Scoping Review., PMID:33800752
Sequencing at lymphoid neoplasm susceptibility loci maps six myeloma risk genes., PMID:33751038
Ultrasound May Suppress Tumor Growth, Inhibit Inflammation, and Establish Tolerogenesis by Remodeling Innatome via Pathways of ROS, Immune Checkpoints, Cytokines, and Trained Immunity/Tolerance., PMID:33628851
First-appearing islet autoantibodies for type 1 diabetes in young children: maternal life events during pregnancy and the child's genetic risk., PMID:33404683
A modern era of personalized medicine in the diagnosis, prognosis, and treatment of prostate cancer., PMID:33039808
Shared Signature of Recent Positive Selection on the TSBP1-BTNL2-HLA-DRA Genes in Five Native Populations from North Borneo., PMID:33022050
Structural Insights into N-terminal IgV Domain of BTNL2, a T Cell Inhibitory Molecule, Suggests a Non-canonical Binding Interface for Its Putative Receptors., PMID:32976909
The Role of B7 Family Molecules in Maternal-Fetal Immunity., PMID:32265918
Chromatin profiling of cortical neurons identifies individual epigenetic signatures in schizophrenia., PMID:31624234
Association of GWAS-supported noncoding area loci rs404860, rs3117098, and rs7775228 with asthma in Chinese Zhuang population., PMID:31605414
[Research achievements and questions on hepatitis B virus reactivation in hematological diseases]., PMID:31597870
BTNL2 germline variants may be involved in the pathogenesis of renal granuloma., PMID:31454127
BTNL2-Ig Protein Attenuates Type 1 Diabetes in Non-Obese Diabetic (NOD) Mice., PMID:30884196
BTNL2 gene polymorphism and sarcoid uveitis., PMID:30872286
Genetic Contribution to the Divergence in Type 1 Diabetes Risk Between Children From the General Population and Children From Affected Families., PMID:30655385
In vivo administration of recombinant BTNL2-Fc fusion protein ameliorates graft-versus-host disease in mice., PMID:30389093
Transethnic, Genome-Wide Analysis Reveals Immune-Related Risk Alleles and Phenotypic Correlates in Pediatric Steroid-Sensitive Nephrotic Syndrome., PMID:29903748
Deep Resequencing of Ulcerative Colitis-Associated Genes Identifies Novel Variants in Candidate Genes in the Korean Population., PMID:29733354
Key HLA-DRB1-DQB1 haplotypes and role of the BTNL2 gene for response to a hepatitis B vaccine., PMID:29534301
Atopobium and Fusobacterium as novel candidates for sarcoidosis-associated microbiota., PMID:29242257
The Roles of Genetic Factors in Kawasaki Disease: A Systematic Review and Meta-analysis of Genetic Association Studies., PMID:29098351
Correlation analysis of the HLA-DPB1*05:01 and BTNL2 genes within the histocompatibility complex region with a clinical phenotype of psoriasis vulgaris in the Chinese Han population., PMID:28581127
HLA-DRA/HLA-DRB5 polymorphism affects risk of sporadic ALS and survival in a southwest Chinese cohort., PMID:28131168
Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations., PMID:28025329
For research use only. Not for human or drug use.
