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Aldafermin ELISA Kit

Catalog #:   KDB73301 Specific References (32) DATASHEET
Sample type: Plasma, Serum
Sensitivity: 33.12 ng/mL
Range: 78.125 - 5,000 ng/mL
Overview

Catalog No.

KDB73301

Detection method

Colorimetric

Sample type

Plasma, Serum

Assay type

Quantitative

Range

78.125 - 5,000 ng/mL

Sensitivity

33.12 ng/mL

Precision

CV<20%

Recovery

80-120%

Shipping

2-8 ℃

Stability and Storage

The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.

Alternative Names

NGM282, CAS: 1616639-03-2

Data Image
References

Advanced Microbiome Therapeutics Accelerate MASLD Recovery by Restoring Intestinal Microbiota Equilibrium and the Gut-Liver Axis in a Mouse Model., PMID:40480642

The effect of aldafermin expressing-Escherichia coli Nissle 1917 along with dietary change on visceral adipose tissue in MASLD mouse model., PMID:40211057

Efficacy and safety of aldafermin for the treatment of metabolic dysfunction-associated steatohepatitis: A systematic review and meta-analysis., PMID:40147589

Clinical Assessment of Common Medications for Nonalcoholic Fatty Liver Disease: A Systematic Review and Bayesian Network Meta-Analysis., PMID:39963857

Efficacy and safety of the FGF19 analog aldafermin for the treatment of nonalcoholic steatohepatitis: a GRADE assessed systematic review and meta-analysis., PMID:39649867

Genetic heterogeneity of engineered Escherichia coli Nissle 1917 strains during scale-up simulation., PMID:39111565

Comparative efficacy of pharmacologic therapies for MASH in reducing liver fat content: Systematic review and network meta-analysis., PMID:39028914

The role of FGF19 in metabolic regulation: insights from preclinical models to clinical trials., PMID:39017679

Efficacy and safety of aldafermin in non-alcoholic steatohepatitis: A systematic review and meta-analysis of randomized controlled trials., PMID:38688423

FGF19 and its analog Aldafermin cooperate with MYC to induce aggressive hepatocarcinogenesis., PMID:38228803

Combined inhibition of bile salt synthesis and intestinal uptake reduces cholestatic liver damage and colonic bile salts in mice., PMID:38074508

Changes in liver metabolic pathways demonstrate efficacy of the combined dietary and microbial therapeutic intervention in MASLD mouse model., PMID:37839774

A randomized, double-blind, placebo-controlled trial of aldafermin in patients with NASH and compensated cirrhosis., PMID:37732990

Effects of FGF19 Analogue Aldafermin in Patients With Bile Acid Diarrhea: A Randomized, Placebo-Control Trial., PMID:37084852

Effect of pharmacological interventions and placebo on liver Histology in nonalcoholic steatohepatitis: A network meta-analysis., PMID:35970684

Pharmacotherapeutic Impact on Nonalcoholic Steatohepatitis Histology: A Systematic Review and Network Meta-analysis., PMID:35814516

Comprehensive Review and Updates on Holistic Approach Towards Non-Alcoholic Fatty Liver Disease Management with Cardiovascular Disease., PMID:35507280

Aldafermin in patients with non-alcoholic steatohepatitis (ALPINE 2/3): a randomised, double-blind, placebo-controlled, phase 2b trial., PMID:35325622

Aldafermin in non-alcoholic steatohepatitis: a cautionary tale for trial design., PMID:35325621

Nonalcoholic steatohepatitis (NASH) cirrhosis: a snapshot of therapeutic agents in clinical development and the optimal design for clinical trials., PMID:35060815

Role of hemagglutinin esterase in replication of SARS-CoV-2., PMID:34749582

A short report on NGM282/aldafermin for the treatment of nonalcoholic steatohepatitis (NASH)., PMID:34727818

Potent suppression of hydrophobic bile acids by aldafermin, an FGF19 analogue, across metabolic and cholestatic liver diseases., PMID:33898959

Recent advances in the treatment of primary sclerosing cholangitis., PMID:33283566

Nonalcoholic Fatty Liver Disease: A Drug Revolution Is Coming., PMID:33115209

The Commensal Microbe Veillonella as a Marker for Response to an FGF19 Analog in NASH., PMID:32794259

Efficacy and Safety of Aldafermin, an Engineered FGF19 Analog, in a Randomized, Double-Blind, Placebo-Controlled Trial of Patients With Nonalcoholic Steatohepatitis., PMID:32781086

Evolving Role for Pharmacotherapy in NAFLD/NASH., PMID:32583961

Timing Is Everything: Improving NASH Histology in Clinical Trials Should Not Be Rushed., PMID:32118303

Multiple therapeutic targets in rare cholestatic liver diseases: Time to redefine treatment strategies., PMID:31771820

NGM282 Improves Liver Fibrosis and Histology in 12 Weeks in Patients With Nonalcoholic Steatohepatitis., PMID:30805949

Effect of NGM282, an FGF19 analogue, in primary sclerosing cholangitis: A multicenter, randomized, double-blind, placebo-controlled phase II trial., PMID:30414864

Datasheet

Document Download

Aldafermin ELISA Kit.pdf

 

$ 1128
Product specifications
96 T 1128

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For research use only. Not for human or drug use.

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Aldafermin ELISA Kit [KDB73301]
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