Catalog No.
YHB93501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg21-Lys180
Predicted molecular weight
20.93 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P01275
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GLP-1(7-36), Incretin hormone, GLP-2, GCG, GLP-1(7-37), OXM, Pro-glucagon, GLP-1, GRPP, OXY
METRNL represses beta-to-alpha cell trans-differentiation to maintain beta cell function under diabetic metabolic stress in mice., PMID:40495021
Effect of glucocorticoid combined with azithromycin on serum inflammatory factors and pulmonary function in children with influenza A virus-induced pneumonia., PMID:40489830
TCPTP inhibition as a novel therapeutic strategy for esophageal squamous cell carcinoma: discovery and efficacy of COH29., PMID:40414512
Transcriptomic characterization of the synergy between human induced pluripotent stem cells-derived liver- and pancreas-on-chip coculture., PMID:40409528
Lactobacillus rhamnosus GG Supernatant Improves GLP-1 Secretion Through Attenuating L Cell Lipotoxicity and Modulating Gut Microbiota in Obesity., PMID:40366615
GC-MS profiling and computational analysis of Balanites aegyptiaca phytoconstituents for antidiabetic activity: insights from network pharmacology and molecular docking., PMID:40328910
Mechanism of interaction between key active ingredients and myosin in tea-stewed beef: Improvement of myosin's structural and functional characteristics., PMID:40252443
Gene Dysregulation and Islet Changes in PDAC-Associated Type 3c Diabetes., PMID:40244011
High GLP1R gene copy numbers associated with microsatellite instability for multiple cancers and with better survival probabilities for glioblastoma., PMID:40207977
Major allelic variants in IRF6 and the association with Non-Syndromic orofacial Clefts: Insights from a Kerala-Based Case-Control study., PMID:40185345
Antidiabetic constituents of Kaempferiae rhizoma: Previously undescribed O-linked diarylheptanoid dimers promoting GLP-1 secretion via PKA-CREB pathway., PMID:40180008
Natural variation in promoters of F3'5'H and ANS correlates with catechins diversification in Thea species of genus Camellia., PMID:40121667
Intronic region polymorphisms of autophagy gene ATG16L1 predispose individuals to Hepatitis B virus infection., PMID:40112491
Bevacizumab, Atezolizumab, and Acetylsalicylic Acid in Recurrent, Platinum-Resistant Ovarian Cancer: The EORTC 1508-GCG Phase II Study., PMID:40100121
Targeting the liquid-liquid phase separation of nucleocapsid broadly inhibits the replication of SARS-CoV-2 strains., PMID:40086356
Blockade of glucagon receptor induces α-cell hypersecretion by hyperaminoacidemia in mice., PMID:40075066
Structural Insights into an Antiparallel Chair-Type G-Quadruplex From the Intron of NOP56 Oncogene., PMID:40047221
Modulation of satiety hormones by Bacteroides thetaiotaomicron, Bacteroides fragilis and their derivatives., PMID:40044987
Ginger extract promotes pancreatic islets regeneration in streptozotocin-induced diabetic rats., PMID:40014427
Regulation of GLP-1 and Glucagon Receptor Function by β-Arrestins in Metabolically Important Cell Types., PMID:39983043
Comparative genetic analysis of pathogenic and attenuated strains of Junín virus., PMID:39921799
Unlocking the multifaceted roles of GLP-1: Physiological functions and therapeutic potential., PMID:39911322
Targeted inhibition of menin promotes β-catenin-mediated GLP-1 expression and improves glucose tolerance in high-fat diet-induced obese mice., PMID:39907684
Vagotomy suppresses food intake by increasing GLP-1 secretion via the M3 AChR-AMPKα pathway in mice., PMID:39848433
Association of Alzheimer's Disease Polygenic Risk Score with Concussion Severity and Recovery Metrics., PMID:39821585
Deciphering the Role of Calcium Signaling Pathway-Associated Single Nucleotide Variants in Susceptibility to Hypertension., PMID:39817473
Improved emulsifying and foaming properties of ovalbumin and antioxidant activity of (-)-gallocatechin gallate: Effects of ultrasound-assisted glycation based on natural deep eutectic solvents and noncovalent binding., PMID:39729656
Targeting central pathway of Glucose-Dependent Insulinotropic Polypeptide, Glucagon and Glucagon-like Peptide-1 for metabolic regulation in obesity and type 2 diabetes., PMID:39723473
Effects of feeding the medium-chain triacylglycerol on GLP-1 secretion in aged Brd4-heterozygous mice, which are a mouse model of aging., PMID:39708424
Molecular Ontology of the Nucleus of Solitary Tract., PMID:39629676
Leupaxin promotes hepatic gluconeogenesis and glucose metabolism by coactivation with hepatic nuclear factor 4α., PMID:39603504
Why does GLP-1 agonist combined with GIP and/or GCG agonist have greater weight loss effect than GLP-1 agonist alone in obese adults without type 2 diabetes?, PMID:39592891
Combining in silico and in vitro approaches for understanding the mechanism of action of the galactomannan extracted from Cassia grandis seeds against colorectal cancer., PMID:39577517
Identification of the Cold-Related Genes COLD11 and OsCTS11 via BSA-seq and Fine Mapping at the Rice Seedling Stage., PMID:39576378
Inhibition mechanisms of α-glucosidase by eight catechins: Kinetic, molecular docking, and surface plasmon resonance analysis., PMID:39547633
The crucial quality marker of Panax ginseng: Glycosylated modified ribonuclease-like storage protein., PMID:39490867
Introducing a hemoglobin G-Makassar variant in HSCs by in vivo base editing treats sickle cell disease in mice., PMID:39489920
Chronic late gestation fetal hyperglucagonaemia results in lower insulin secretion, pancreatic mass, islet area and beta- and α-cell proliferation., PMID:39383208
Association of uric acid and fructose levels in polycystic ovary syndrome., PMID:39380170
Pea protein hydrolysate stimulates GLP-1 secretion in NCI-H716 cells via simultaneously activating the sensing receptors CaSR and PepT1., PMID:39302035
Synaptic and membrane properties of cholinergic interneurons in the striatum of aristaless-related homeobox gene mutant mice., PMID:39287775
Single-nucleus RNA sequencing reveals cell types, genes, and regulatory factors influencing melanogenesis in the breast muscle of Xuefeng black-bone chicken., PMID:39278114
The Potential Mechanisms of Catechins in Tea for Anti-Hypertension: An Integration of Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulation., PMID:39272451
[A new era for incretins : from GLP-1 receptor agonists to co-agonists and poly-agonists]., PMID:39262368
The effect of genetic polymorphisms in STIM1 and ORAI1 on erythropoietin resistance in Egyptian patients with end-stage renal disease., PMID:39214396
Garlic Extract Promotes Pancreatic Islet Neogenesis Through α-to-β-Cell Transdifferentiation and Normalizes Glucose Homeostasis in Diabetic Rats., PMID:39205537
Generation and application of novel hES cell reporter lines for the differentiation and maturation of hPS cell-derived islet-like clusters., PMID:39191834
The Gut Microbial Lipid Metabolite 14(15)-EpETE Inhibits Substance P Release by Targeting GCG/PKA Signaling to Relieve Cisplatin-Induced Nausea and Vomiting in Rats., PMID:39187454
A CYP11A1 homozygous exonic variant inducing an alternative splicing, frameshift and truncation in a family with congenital adrenal hyperplasia., PMID:39157388
Identification of novel HLA-C*17:78 allele in North Indian individuals., PMID:39132706