Catalog No.
YHF34402
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Phe178-Ala231
Predicted molecular weight
33.88 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P60201
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Lipophilin, PLP1, Myelin proteolipid protein, PLP
Neuroglial Pathophysiology of Leukodystrophies., PMID:40500501
Role of Long Non-Coding RNA X-Inactive-Specific Transcript (XIST) in Neuroinflammation and Myelination: Insights from Cerebral Organoids and Implications for Multiple Sclerosis., PMID:40407589
Pelizaeus-Merzbacher Disease as a Cause of Early-Onset Developmental Delay: A Case Report., PMID:40376385
Temporal transcriptomic changes in the THY-Tau22 mouse model of tauopathy display cell type- and sex-specific differences., PMID:40336141
Dynamic Proteome Changes in Cuprizone-Induced Demyelination and Remyelination in the Mouse Brain., PMID:40305778
Markers of axonal injury in blood and tissue triggered by acute and chronic demyelination., PMID:40278829
Enteric glia regulate Paneth cell secretion and intestinal microbial ecology., PMID:40227232
A copy number variant overlapping the 3'UTR of PLP1 causes spastic paraplegia., PMID:40199965
Toxoplasma induced cytokine release syndrome is critically dependent on the expression of pore-forming Perforin-Like Protein-1., PMID:40166190
Interrogating mediators of single-cell transcriptional changes in the acute damaged cerebral cortex: Insights into endothelial-astrocyte interactions., PMID:40090391
Unique DUP-TRP/INV-DUP Structure Detected by Long-Read Sequencing., PMID:40070183
SOX10-Mediated Regulation of Enteric Glial Phenotype in vitro and its Relevance for Neuroinflammatory Disorders., PMID:39982575
Evaluation of Toxoplasma gondii Perforin-like Proteins (PLPs) to Find the Potential Epitopes for Immunization through in silico Approach., PMID:39901670
Enhancer-driven Shh signaling promotes glia-to-mesenchyme transition during bone repair., PMID:39865079
Conformational Antibodies to Proteolipid Protein-1 and Its Peripheral Isoform DM20 in Patients With CNS Autoimmune Demyelinating Disorders., PMID:39823554
The Polygenic Nature of Multiple Sclerosis: Genetic Variants, Immunological Modulation, and Environmental Connections., PMID:39810445
Loss of NF1 Accelerates Uveal and Intradermal Melanoma Tumorigenesis, and Oncogenic GNAQ Transforms Schwann Cells., PMID:39804140
Clinical characteristics of the Ala21Val variant in the myelin proteolipid protein 1 (PLP1) gene associated with Pelizaeus-Merzbacher disease in a Brazilian male patient., PMID:39762264
Docking‑based virtual screening of BRD4 (BD1) inhibitors: assessment of docking methods, scoring functions and in silico molecular properties., PMID:39696643
Fractal analysis to assess the differentiation state of oligodendroglia in culture., PMID:39638053
Purification of plasmid DNA using a novel two stage chromatography process., PMID:39612883
PLP1-Targeting Antisense Oligonucleotides Improve FOXG1 Syndrome Mice., PMID:39409184
Identification of key regulatory genes involved in myelination after spinal cord injury by GSEA analysis., PMID:39326824
Inherited white matter disorders: Hypomyelination (myelin disorders)., PMID:39322379
Knockdown of Rab9 Recovers Defective Morphological Differentiation Induced by Chemical ER Stress Inducer or PMD-Associated PLP1 Mutant Protein in FBD-102b Cells., PMID:39311306
CRISPR/CasRx-Mediated Knockdown of Rab7B Restores Incomplete Cell Shape Induced by Pelizaeus-Merzbacher Disease-Associated PLP1 p.Ala243Val., PMID:39280331
Schwann cell transient receptor potential ankyrin 1 (TRPA1) ortholog in zebrafish larvae mediates chemotherapy-induced peripheral neuropathy., PMID:39238161
Single-Nucleus Landscape of Glial Cells and Neurons in Alzheimer's Disease., PMID:39153159
A rapidly progressive multiple system atrophy-cerebellar variant model presenting marked glial reactions with inflammation and spreading of α-synuclein oligomers and phosphorylated α-synuclein aggregates., PMID:38986725
Myelination by signaling through Arf guanine nucleotide exchange factor., PMID:38894552
Plp1-expresssing perineuronal DRG cells facilitate colonic and somatic chronic mechanical pain involving Piezo2 upregulation in DRG neurons., PMID:38743566
Integrated analysis of transcriptional changes in major depressive disorder: Insights from blood and anterior cingulate cortex., PMID:38628773
Pelizaeus-Merzbacher disease: on the cusp of myelin medicine., PMID:38582621
Phosphatase and Tensin Homolog Inhibition in Proteolipid Protein 1-Expressing Cells Stimulates Neurogenesis and Gliogenesis in the Postnatal Enteric Nervous System., PMID:38540765
Dysregulation of the renin-angiotensin system in vascular dementia., PMID:38454306
Single cell transcriptome analysis of the THY-Tau22 mouse model of Alzheimer's disease reveals sex-dependent dysregulations., PMID:38453894
Identification and preliminary analysis of hub genes associated with bladder cancer progression by comprehensive bioinformatics analysis., PMID:38307969
Loss of Pax3 causes reduction of melanocytes in the developing mouse cochlea., PMID:38278860
Generation of a fluorescent oligodendrocyte reporter line in human induced pluripotent stem cells., PMID:38219302
Generation of Pelizaeus-Merzbacher disease (PMD) mutant (PLP1-C33Y) in induced pluripotent stem cell (iPSC) by CRISPR/Cas9 genome editing., PMID:38104430
Enhanced oxidative phosphorylation, re-organized intracellular signaling, and epigenetic de-silencing as revealed by oligodendrocyte translatome analysis after contusive spinal cord injury., PMID:38040794
Lipidomic Analysis Reveals Differences in the Extent of Remyelination in the Brain and Spinal Cord., PMID:38018851
Synaptic Involvement of the Human Amygdala in Parkinson's Disease., PMID:37947401
Microglia-mediated demyelination protects against CD8+ T cell-driven axon degeneration in mice carrying PLP defects., PMID:37903797
From drab to Fab; PLP1's fit is redressed for MS., PMID:37801515
The natural history of Pelizaeus-Merzbacher disease caused by PLP1 duplication: A multiyear case series., PMID:37636890
Pathogenic myelin-specific antibodies in multiple sclerosis target conformational proteolipid protein 1-anchored membrane domains., PMID:37561592
Optical genome mapping in an atypical Pelizaeus-Merzbacher prenatal challenge., PMID:37560384
Enhanced oxidative phosphorylation, re-organized intracellular signaling, and epigenetic de-silencing as revealed by oligodendrocyte translatome analysis after contusive spinal cord injury., PMID:37546871
For research use only. Not for human or drug use.
