Catalog No.
YHN55101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser591-Glu851
Predicted molecular weight
30.48 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q99459
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CDC5L, PCDC5RP, KIAA0432, Cdc5-like protein, Cell division cycle 5-like protein, Pombe cdc5-related protein
Proteomics analysis explored the changes in the tumor microenvironment of CT26 tumor-bearing mice after microwave ablation., PMID:40317156
EIF4A3 Promotes Cell Proliferation via CDC5L Upregulation in Human Breast Cancer Cells., PMID:40092703
A Systems Biology Approach for Prioritizing ASD Genes in Large or Noisy Datasets., PMID:40076702
Prp19/CDC5L promotes gastric cancer via activation of the MAPK pathway-mediated homologous recombination., PMID:39990666
Identification of biomarkers for chronic lymphocytic leukemia risk: a proteome-wide Mendelian randomization study., PMID:39751938
IGF2BP1 promotes multiple myeloma with chromosome 1q gain via increasing CDC5L expression in an m6A-dependent manner., PMID:39534570
Expression, DNA methylation pattern and transcription factor EPB41L3 in gastric cancer: a study of 262 cases., PMID:39354571
m6A modification of CDC5L promotes lung adenocarcinoma progression through transcriptionally regulating WNT7B expression., PMID:39113868
SAFER: sub-hypergraph attention-based neural network for predicting effective responses to dose combinations., PMID:39080535
SAFER: sub-hypergraph attention-based neural network for predicting effective responses to dose combinations., PMID:38746131
BCAS2 regulates oocyte meiotic prophase I by participating in mRNA alternative splicing., PMID:38085152
Elevated level of PLRG1 is critical for the proliferation and maintenance of genome stability of tumor cells., PMID:37817442
FOXA1 prolongs S phase and promotes cancer progression in non-small cell lung cancer through upregulation of CDC5L and activation of the ERK1/2 and JAK2 pathways., PMID:37658700
Knockdown of LncRNA DICER1-AS1 arrests the cell cycle, inhibits cell proliferation, and induces cell apoptosis by regulating CDC5L nuclear transfer in osteosarcoma., PMID:37310074
BCAS2 regulates granulosa cell survival by participating in mRNA alternative splicing., PMID:37248466
Analysing transcriptomic signatures and identifying potential genes for the protective effect of inactivated COVID-19 vaccines., PMID:37096063
The general law of plasma proteome alterations occurring in the lifetime of Chinese individuals reveals the importance of immunity., PMID:36084955
Identification of Signal Pathways and Hub Genes of Pulmonary Arterial Hypertension by Bioinformatic Analysis., PMID:36072642
Paraquat-induced oxidative stress regulates N6-methyladenosine (m6A) modification of long noncoding RNAs in Neuro-2a cells., PMID:35453019
Evaluation of the TRIP13 level in breast cancer and insights into potential molecular pathways., PMID:35322916
[Bioinformatics-based identification of key genes CDC5L and related pathways in osteosarcoma and Ewing's sarcoma]., PMID:35322620
HuR Promotes the Progression of Gastric Cancer through Mediating CDC5L Expression., PMID:35313568
Analysis of expression profiles and bioinformatics suggests that plasma exosomal circular RNAs may be involved in ischemic stroke in the Chinese Han population., PMID:35067794
Protein network analysis to prioritize key genes in amyotrophic lateral sclerosis., PMID:34918006
Downregulation of DEAD-box helicase 21 (DDX21) inhibits proliferation, cell cycle, and tumor growth in colorectal cancer via targeting cell division cycle 5-like (CDC5L)., PMID:34903139
A distinct complex of PRP19-related and trypanosomatid-specific proteins is required for pre-mRNA splicing in trypanosomes., PMID:34850936
KIF4A Regulates the Progression of Pancreatic Ductal Adenocarcinoma through Proliferation and Invasion., PMID:34805404
ZNF76 predicts prognosis and response to platinum chemotherapy in human ovarian cancer., PMID:34793589
Integrated Bioinformatics Analysis Reveals Marker Genes and Potential Therapeutic Targets for Pulmonary Arterial Hypertension., PMID:34573320
Comparative Transcriptional Analysis of Pulmonary Arterial Hypertension Associated With Three Different Diseases., PMID:34336829
CDC5L promotes early chondrocyte differentiation and proliferation by modulating pre-mRNA splicing of SOX9, COL2A1, and WEE1., PMID:34298017
NSMF promotes the replication stress-induced DNA damage response for genome maintenance., PMID:33963872
A Molecular Interaction Map of Klebsiella pneumoniae and Its Human Host Reveals Potential Mechanisms of Host Cell Subversion., PMID:33679637
Transcription-translation error: In-silico investigation of the structural and functional impact of deleterious single nucleotide polymorphisms in GULP1 gene., PMID:33665355
Long Noncoding RNA LINC00963 Promotes CDC5L-Mediated Malignant Progression in Gastric Cancer., PMID:33376349
Prognostic value of aberrantly expressed methylation genes in human hepatocellular carcinoma., PMID:32955083
The effects of p53 gene inactivation on mutant proteome expression in a human melanoma cell model., PMID:32866596
Identification of CDC5L as bridge gene between chronic obstructive pulmonary disease and lung adenocarcinoma., PMID:32543224
ANXA7 promotes the cell cycle, proliferation and cell adhesion-mediated drug resistance of multiple myeloma cells by up-regulating CDC5L., PMID:32526706
Gene regulation could be attributed to TCF3 and other key transcription factors in the muscle of pubertal heifers., PMID:32432381
Identification of Co-expressed Genes Between Atrial Fibrillation and Stroke., PMID:32265825
Circ-PGAM1 promotes malignant progression of epithelial ovarian cancer through regulation of the miR-542-3p/CDC5L/PEAK1 pathway., PMID:32167655
Depletion of CDC5L inhibits bladder cancer tumorigenesis., PMID:31897231
ADNP differentially interact with genes/proteins in correlation with aging: a novel marker for muscle aging., PMID:31264075
Expression Profiles of Long Noncoding RNAs in Intranasal LPS-Mediated Alzheimer's Disease Model in Mice., PMID:30809552
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability., PMID:30150775
A novel and effective inhibitor combination involving bortezomib and OTSSP167 for breast cancer cells in light of label-free proteomic analysis., PMID:29948483
Oncogenic Properties of NEAT1 in Prostate Cancer Cells Depend on the CDC5L-AGRN Transcriptional Regulation Circuit., PMID:29871935
Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors., PMID:29547724
CDC5L drives FAH expression to promote metabolic reprogramming in melanoma., PMID:29371990
For research use only. Not for human or drug use.
