Catalog No.
YHN55001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Asn161
Predicted molecular weight
21.00 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q63ZY3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ankyrin repeat domain-containing protein 25, SRC-interacting protein, SRC-1-interacting protein, SRC1-interacting protein, ANKRD25, KIAA1518, MXRA3, KN motif and ankyrin repeat domain-containing protein 2, Matrix-remodeling-associated protein 3, KANK2, SIP
From stem cells to skin: ADSCP6 peptide's role in transforming scar therapy., PMID:40348095
Pan-Cancer Analysis of KANK2: Clinical and Molecular Insights into Tumor Progression and Therapeutic Implications., PMID:39895803
Transcriptional mechanism of E2F1/TFAP2C/NRF1 in regulating KANK2 gene in nephrotic syndrome., PMID:38253280
Gene expression analysis revealed downregulation of complement receptor 1 in clonal B cells in cold agglutinin disease., PMID:38133636
Cross species systems biology discovers glial DDR2, STOM, and KANK2 as therapeutic targets in progressive supranuclear palsy., PMID:37919278
USP39 promotes hepatocellular carcinogenesis through regulating alternative splicing in cooperation with SRSF6/HNRNPC., PMID:37821439
Talin2 and KANK2 functionally interact to regulate microtubule dynamics, paclitaxel sensitivity and cell migration in the MDA-MB-435S melanoma cell line., PMID:37460977
Integrative analysis of the proteome and transcriptome in gastric cancer identified LRP1B as a potential biomarker., PMID:36606427
Selection signature analyses and genome-wide association reveal genomic hotspot regions that reflect differences between breeds of horse with contrasting risk of degenerative suspensory ligament desmitis., PMID:35866615
HSP70 Ameliorates Septic Lung Injury via Inhibition of Apoptosis by Interacting with KANK2., PMID:35327602
Identification of the shared gene signatures and pathways between sarcopenia and type 2 diabetes mellitus., PMID:35271662
Exploration of autoantibody responses in canine diabetes using protein arrays., PMID:35169238
Twenty-Five Novel Loci for Carotid Intima-Media Thickness: A Genome-Wide Association Study in >45 000 Individuals and Meta-Analysis of >100 000 Individuals., PMID:34852643
Nephrotic-syndrome-associated mutation of KANK2 induces pathologic binding competition with physiological interactor KIF21A., PMID:34274317
Tissue distribution and subcellular localization of the family of Kidney Ankyrin Repeat Domain (KANK) proteins., PMID:33253712
Therapeutic effects of KANK2 in myocardial infarction rats might be associated with the NF-κB p65 inhibition., PMID:32570033
CacyBP/SIP in the rat spinal cord in norm and after transection - Influence on the phosphorylation state of ERK1/2 and p38 kinases., PMID:32544715
The Neuroprotective Effect of Steroid Receptor Coactivator-Interacting Protein (SIP) in Astrocyte Model of 1-Methyl-4-Phenylpyridinium (MPP⁺)-Induced Parkinson's Disease., PMID:31376345
A mechano-signalling network linking microtubules, myosin IIA filaments and integrin-based adhesions., PMID:31114072
Discovery and Characterization of Recurrent, Targetable ALK Fusions in Leiomyosarcoma., PMID:30518629
Genome-wide identification of transcription factors that are critical to non-small cell lung cancer., PMID:30031117
Steroid Receptor Coactivator-Interacting Protein (SIP) Suppresses Myocardial Injury Caused by Acute Pancreatitis., PMID:29765014
Hereditary palmoplantar keratodermas. Part I. Non-syndromic palmoplantar keratodermas: classification, clinical and genetic features., PMID:29489036
Structural basis for the recognition of kinesin family member 21A (KIF21A) by the ankyrin domains of KANK1 and KANK2 proteins., PMID:29183992
Collar occupancy: A new quantitative imaging tool for morphometric analysis of oligodendrocytes., PMID:29174019
Kank2 activates talin, reduces force transduction across integrins and induces central adhesion formation., PMID:27548916
Proximity biotinylation provides insight into the molecular composition of focal adhesions at the nanometer scale., PMID:27303058
Evolutionary and developmental analysis reveals KANK genes were co-opted for vertebrate vascular development., PMID:27292017
Steroid receptor co-activator interacting protein (SIP) mediates EGF-stimulated expression of the prostaglandin synthase COX2 and prostaglandin release in human myometrium., PMID:27161844
Association of liprin β-1 with kank proteins in melanoma., PMID:26739330
KANK deficiency leads to podocyte dysfunction and nephrotic syndrome., PMID:25961457
Mutation in KANK2, encoding a sequestering protein for steroid receptor coactivators, causes keratoderma and woolly hair., PMID:24671081
Kank proteins: a new family of ankyrin-repeat domain-containing proteins., PMID:17996375
For research use only. Not for human or drug use.
