Catalog No.
YHC87301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser11-Leu206
Predicted molecular weight
24.70 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P11234
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ras-related protein Ral-B, RALB
RalB promotes lymph node metastasis in tongue squamous cell carcinoma., PMID:40208483
RalB uncoupling from exocyst is required for endothelial Weibel-Palade body exocytosis., PMID:40172988
Changes in the Proteomic Profile After Audiogenic Kindling in the Inferior Colliculus of the GASH/Sal Model of Epilepsy., PMID:40076950
Double-module ratio as a patient-based real-time quality control index for small shift detection and comparative assay., PMID:40010660
A large-scale proteomics resource of circulating extracellular vesicles for biomarker discovery in pancreatic cancer., PMID:39693144
Rlip76 in ageing and Alzheimer's disease: Focus on oxidative stress and mitochondrial mechanisms., PMID:39617058
The shared genetic landscape of polycystic ovary syndrome and breast cancer: convergence on ER + breast cancer but not ER- breast cancer., PMID:39587695
Critical role for platelet Ral GTPases in regulating venous thrombosis in mice., PMID:39454881
Proteomic Characterization of Corneal Epithelial and Stromal Cell-Derived Extracellular Vesicles., PMID:39408670
RalB uncoupled exocyst mediates endothelial Weibel-Palade body exocytosis., PMID:39345530
The RAL Small G Proteins Are Clinically Relevant Targets in Triple Negative Breast Cancer., PMID:39272901
Phosphatidylinositol-3-phosphate mediates Arc capsid secretion through the multivesicular body pathway., PMID:39178227
SH-Alb inhibits phenotype remodeling of pro-fibrotic macrophage to attenuate liver fibrosis through SIRT3-SOD2 axis., PMID:38876053
Roseburia intestinalis sensitizes colorectal cancer to radiotherapy through the butyrate/OR51E1/RALB axis., PMID:38412097
Phosphatidylinositol 3-phosphate mediates Arc capsids secretion through the multivesicular body pathway., PMID:38187623
Generation of novel in vitro flexible kidney organoid model to investigate the role of extracellular vesicles in induction of nephrogenesis., PMID:38110951
Structural insights into the complex of oncogenic KRas4BG12V and Rgl2, a RalA/B activator., PMID:37833074
Papillary renal neoplasm with reverse polarity: a clinicopathologic study of 43 cases with a focus on the expression of KRAS signaling pathway downstream effectors., PMID:37797754
Identification and validation of autophagy-related genes in Kawasaki disease., PMID:37085930
A Large-Scale Proteomics Resource of Circulating Extracellular Vesicles for Biomarker Discovery in Pancreatic Cancer., PMID:36993200
Association between Downstream Taste Signaling Genes, Oral Microbiome, and Severe Early Childhood Caries., PMID:36613519
Ral GTPases are critical regulators of spinal cord myelination and homeostasis., PMID:36170840
Gene Expression Characteristics of Tumor and Adjacent Non-Tumor Tissues of Pancreatic Ductal Adenocarcinoma (PDAC) In-Silico., PMID:35891953
The RAL Enigma: Distinct Roles of RALA and RALB in Cancer., PMID:35626682
Identification of Tumor-Suppressive miR-30e-3p Targets: Involvement of SERPINE1 in the Molecular Pathogenesis of Head and Neck Squamous Cell Carcinoma., PMID:35409173
Membrane extraction by calmodulin underpins the disparate signalling of RalA and RalB., PMID:35318680
A proximity proteomics screen in three-dimensional spheroid cultures identifies novel regulators of lumen formation., PMID:34815476
Identification of Gene Co-Expression Modules and Core Genes Related to Immune Disorders in Major Depression Disorder., PMID:34785941
Dysregulation of RalA signaling through dual regulatory mechanisms exerts its oncogenic functions in hepatocellular carcinoma., PMID:34767674
Determining oncogenic patterns and cancer predisposition through the transcriptomic profile in Mitchell-Riley syndrome with heterotopic gastric mucosa and duodenal atresia: a case report., PMID:34715892
A phase i study of ixazomib and erlotinib in patients with advanced solid tumors., PMID:34468905
Exocyst protein subnetworks integrate Hippo and mTOR signaling to promote virus detection and cancer., PMID:34348154
The small G-protein RalA promotes progression and metastasis of triple-negative breast cancer., PMID:34118960
The RAL signaling network: Cancer and beyond., PMID:34074494
RLIP76: A Structural and Functional Triumvirate., PMID:34064388
Ral GTPase-activating protein regulates the malignancy of pancreatic ductal adenocarcinoma., PMID:34009715
Absolute Quantitation of GTPase Protein Abundance., PMID:33977471
Plant Rho GTPase signaling promotes autophagy., PMID:33794369
Reductively modified albumin attenuates DSS-Induced mouse colitis through rebalancing systemic redox state., PMID:33601276
MicroRNA-139 inhibits pancreatic-cancer carcinogenesis by suppressing RalB via the Ral/RAC/PI3K pathway., PMID:33290747
Affinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPases., PMID:33214225
RALB GTPase: a critical regulator of DR5 expression and TRAIL sensitivity in KRAS mutant colorectal cancer., PMID:33122623
Prevalence of autoantibodies against Ras-like GTPases, RalA, in patients with gastric cancer., PMID:32765875
Regulation and repurposing of nutrient sensing and autophagy in innate immunity., PMID:32627660
Control of endothelial tubulogenesis by Rab and Ral GTPases, and apical targeting of caveolin-1-labeled vacuoles., PMID:32569321
The GTPase KRAS suppresses the p53 tumor suppressor by activating the NRF2-regulated antioxidant defense system in cancer cells., PMID:32001619
NMR resonance assignments for the active and inactive conformations of the small G protein RalA., PMID:31916136
Dual-targeting of EGFR and Neuropilin-1 attenuates resistance to EGFR-targeted antibody therapy in KRAS-mutant non-small cell lung cancer., PMID:31521695
SIRT2 and Lysine Fatty Acylation Regulate the Activity of RalB and Cell Migration., PMID:31433161
Ral GTPase Activation by Downregulation of RalGAP Enhances Oral Squamous Cell Carcinoma Progression., PMID:31329042
For research use only. Not for human or drug use.
