Catalog No.
YHB90601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg58-Leu176
Predicted molecular weight
15.30 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P01042
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Kininogen-1, Kallidin II, Fitzgerald factor, KNG, Alpha-2-thiol proteinase inhibitor, Kallidin I, Williams-Fitzgerald-Flaujeac factor, High molecular weight kininogen, HMWK, KNG1, Ile-Ser-Bradykinin, BDK
Cigarette Smoke-Induced PPAR Signaling Dysregulation Accelerates Alzheimer's Disease Pathogenesis and Cognitive Decline in 5xFAD Mice., PMID:40513939
Rubia cordifolia L. extract ameliorates vitiligo by inhibiting the CXCL10/CXCL9/STAT1 signaling pathway., PMID:40412781
Omics data integration analysis identified new biological insights into chronic antibody-mediated rejection (CAMR)., PMID:39979925
Platform-dependent effects of genetic variants on plasma APOL1 and their implications for kidney disease., PMID:39975113
[Berberine ameliorates coronary artery endothelial cell injury in Kawasaki disease through complement and coagulation cascades]., PMID:39825659
KNG1 mutations (c.618 T > G and c.1165C > T) cause disruption of the Cys206-Cys218 disulfide bond and truncation of the D5 domain leading to hereditary high molecular weight kininogen deficiency., PMID:39800040
Multiorgan proteomic analysis of infected animal models predict potential host factors for chikungunya virus., PMID:39764561
PAI-1 promotes human endometrial stromal decidualization via inhibiting VEGFR2/PI3K/AKT signaling pathway mediated F-actin reorganization., PMID:39718443
Alpha-fetoprotein, glypican-3, and kininogen-1 as biomarkers for the diagnosis of hepatocellular carcinoma., PMID:39660335
Proteomic identification of potential biomarkers for heat tolerance in Caracu beef cattle using high and low thermotolerant groups., PMID:39538142
Scalp acupuncture alleviates remote hippocampal damage in MCAO rats by inhibiting neuroinflammation: A TMT-based proteomics analysis., PMID:39521322
Gene polymorphisms of miR-323b and miR-1343 that regulate kininogen L are associated with schizophrenia susceptibility: A preliminary population‑based study., PMID:39465687
Causal relationships between three plasma proteins and non-alcoholic fatty liver disease, mediated by Epstein-Barr virus EA-D antibody levels: a mendelian randomization study., PMID:39463412
Combination of Structural Analysis and Proteomics Strategy Revealed the Mechanism of Ultrasound-Assisted Cold Plasma Regulating Shrimp Allergy., PMID:39356241
The pro-atherogenic effects and the underlying mechanisms of chronic bisphenol S (BPS) exposure in apolipoprotein E-deficient mice., PMID:39342757
G-Protein Signaling in Alzheimer's Disease: Spatial Expression Validation of Semi-supervised Deep Learning-Based Computational Framework., PMID:39327003
Expression and predictive value of serum core fucosylated low molecular weight kininogen and alpha-galactosylated antibodies in patients with hepatic fibrosis., PMID:39311786
Integrated data driven analysis identifies potential candidate genes associated with PCOS., PMID:39243549
[Analysis of two consanguineous Chinese pedigrees affected with Hereditary prokallikrein deficiency and High molecular weight kininogen deficiency]., PMID:39217484
The trajectory of vesicular proteomic signatures from HBV-HCC by chitosan-magnetic bead-based separation and DIA-proteomic analysis., PMID:39207047
Derivation and external validation of mass spectrometry-based proteomic model using machine learning algorithms to predict plaque rupture in patients with acute coronary syndrome., PMID:39117035
Application of Proteomics and Machine Learning Methods to Study the Pathogenesis of Diabetic Nephropathy and Screen Urinary Biomarkers., PMID:38949094
Identification and quantification of serum KIN17 protein based on ELISA assay and exploring its clinical diagnostic value in liver cancer., PMID:38949046
Candidate protein biomarkers in chronic kidney disease: a proteomics study., PMID:38890379
Identification of Candidate Protein Biomarkers Associated with Domoic Acid Toxicosis in Cerebrospinal Fluid of California Sea Lions (Zalophus californianus)., PMID:38807289
Effects of foetal size, sex and developmental stage on adaptive transcriptional responses of skeletal muscle to intrauterine growth restriction in pigs., PMID:38605102
Causal relationship between inflammatory factors and cerebral small vessel disease: Univariate, multivariate, and summary-data-based mendelian randomization analysis., PMID:38340139
A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels., PMID:38320121
Expression of Inflammatory Genes in Murine Lungs in a Model of Experimental Pulmonary Hypertension: Effects of an Antibody-Based Targeted Delivery of Interleukin-9., PMID:38247549
Proteomic profiling identifies SPP1 associated with rapidly progressive interstitial lung disease in anti-MDA5-positive dermatomyositis., PMID:38167532
A comprehensive proteomic profiling of urinary exosomes and the identification of early non-invasive biomarker in patients with coronary artery disease., PMID:38151158
Introducing Albumin and Interleukin 6 as Common Critical Dysregulated Proteins Between Migraine and Gliosarcoma., PMID:38107530
Identification of postnatal development dependent genes and proteins in porcine epididymis., PMID:38049726
A mechanism for hereditary angioedema caused by a methionine-379-to-lysine substitution in kininogens., PMID:37992228
Cerebrospinal Fluid Proteomic Profiles in Patients with Postherpetic Neuralgia., PMID:37966014
Network pharmacology-and molecular docking-based investigation of Danggui blood-supplementing decoction in ischaemic stroke., PMID:37932893
TMT-Based Proteomics Reveal the Mechanism of Action of Amygdalin against Rheumatoid Arthritis in a Rat Model through Regulation of Complement and Coagulation Cascades., PMID:37894605
Label-free quantitative proteomics in serum reveals candidate biomarkers associated with low bone mineral density in Mexican postmenopausal women., PMID:37874452
Decoding Systems Biology of Inflammation Signatures in Cancer Pathogenesis: Pan-Cancer Insights from 12 Common Cancers., PMID:37861711
High molecular weight kininogen interactions with the homologs prekallikrein and factor XI: importance to surface-induced coagulation., PMID:37813198
Proteome-wide mendelian randomization identifies causal plasma proteins in venous thromboembolism development., PMID:37537391
An HBV susceptibility variant of KNG1 modulates the therapeutic effects of interferons α and λ1 in HBV infection by promoting MAVS lysosomal degradation., PMID:37442062
Proteomic-based identification of APCS as candidate protein for diagnosis of patients exhibiting anti-tubercular drug induced liver injury., PMID:37349331
Screening and bioinformatics analysis of senile osteoporosis genes based on GEO database., PMID:37318459
Proteomics reveals specific biological changes induced by the normothermic machine perfusion of donor kidneys with a significant up-regulation of Latexin., PMID:37041202
Identifying potential biomarkers for the diagnosis and treatment of IgA nephropathy based on bioinformatics analysis., PMID:36978098
Systematic review of type 1 diabetes biomarkers reveals regulation in circulating proteins related to complement, lipid metabolism, and immune response., PMID:36865103
A Preliminary Study in Immune Response of BALB/c and C57BL/6 Mice with a Locally Allergic Rhinitis Model., PMID:36797980
Gene Mutations Linked to Hereditary Angioedema in Solitary Angioedema Patients With Normal C1 Inhibitor., PMID:36787826
Identification of Prognostic Markers of DNA Damage and Oxidative Stress in Diagnosing Papillary Renal Cell Carcinoma Based on High-Throughput Bioinformatics Screening., PMID:36785669
For research use only. Not for human or drug use.
