Catalog No.
YHB89201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser74-Pro165
Predicted molecular weight
37.21 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P00973
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
E18/E16, (2-5')oligo(A) synthase 1, 2-5A synthase 1, 2'-5'-oligoadenylate synthase 1, OAS1, OIAS, p46/p42 OAS
The puzzling regulation of the interferon signaling system by the p53 tumor suppressor protein., PMID:40512405
Proliferative arrest induces neuronal differentiation and innate immune responses in normal and Creutzfeldt-Jakob Disease agent (CJ) infected rat septal neurons., PMID:40434970
Genetic Determinants of Colonic Diverticulosis-A Systematic Review., PMID:40428403
Structural basis for OAS2 regulation and its antiviral function., PMID:40412389
Conceptus signaling markers in immune cells enhance pregnancy prediction in beef cattle., PMID:40394099
Identification and validation of a 9-RBPs-related gene signature associated with prognosis and immune infiltration in bladder cancer based on bioinformatics analysis and machine learning., PMID:40376515
Genetic Variants in the NOD-like Receptor Signaling Pathway Are Associated with HIV-1/AIDS in a Northern Chinese Population., PMID:40331958
Verification of biological markers of subacute cutaneous lupus erythematosus via TMT labelling proteomics combined with transcriptome data., PMID:40323689
METTL3 depletion blocks vesicular stomatitis virus replication in pancreatic cancer cells through the establishment of an intrinsic antiviral state., PMID:40214229
Construction of a circRNA-miRNA-mRNA Regulatory Network for the Immune Regulation of Lung Adenocarcinoma., PMID:40211126
Analysis and validation of hub genes for atherosclerosis and AIDS and immune infiltration characteristics based on bioinformatics and machine learning., PMID:40210656
Rescue of a unique ovine parainfluenza virus type 3 strain via Red/ET assembly., PMID:40147559
BRCA1 regulates glucose and lipid metabolism in diabetes mellitus with metabolic dysfunction-associated steatotic liver disease via the PI3K/Akt signaling pathway., PMID:40138287
Mpox virus poxin-schlafen fusion protein suppresses innate antiviral response by sequestering STAT2., PMID:40066622
Rhinoviral Infection of the Human Lung Vascular Endothelium May Protect From the Secondary Infection With Rhinovirus RV-16., PMID:40051189
Switching of OAS1 splicing isoforms overcomes SNP-derived vulnerability to SARS-CoV-2 infection., PMID:40025489
A single-cell map of patients with non-small cell lung cancer harboring rare-driver mutations after anti-PD-1 treatment., PMID:40021042
Classical Swine Fever Virus Envelope Glycoproteins Erns, E1, and E2 Activate IL-10-STAT1-MX1/OAS1 Antiviral Pathway via Replacing Classical IFNα/β., PMID:40001503
The African swine fever virus gene MGF_360-4L inhibits interferon signaling by recruiting mitochondrial selective autophagy receptor SQSTM1 degrading MDA5 antagonizing innate immune responses., PMID:39998221
Robust antiviral innate immune response and miRNA regulatory network were identified in ZIKV-infected cells: implications in the pathogenesis of ZIKV infection., PMID:39955676
Heterogeneity of OAS family expression in tuberculosis and the impact of different sample selection: a comprehensive analysis., PMID:39864306
OAS1: A Protective Mechanism for Alzheimer's Disease? An Exploration of Data and Possible Mechanisms., PMID:39859237
Ethanol Disrupts the Protective Crosstalk Between Macrophages and HBV-Infected Hepatocytes., PMID:39858451
Integrated Mendelian randomization and single-cell RNA-sequencing analyses identified OAS1 as a novel therapeutic target for erectile dysfunction via targeting fibroblasts., PMID:39716299
Investigating the clinical significance of OAS family genes in breast cancer: an in vitro and in silico study., PMID:39633486
Modulation of the Gut-Lung Axis by Water Kefir and Kefiran and Their Impact on Toll-like Receptor 3-Mediated Respiratory Immunity., PMID:39595633
OAS1 induces endothelial dysfunction and promotes monocyte adhesion through the NFκB pathway in atherosclerosis., PMID:39571957
Proteome modulation triggers potent antiviral response in Japanese Encephalitis Virus infected human macrophages., PMID:39520552
Uncovering cell-type-specific immunomodulatory variants and molecular phenotypes in COVID-19 using structurally resolved protein networks., PMID:39504244
Association of OAS1 and MxA variants with COVID-19 in Pakistani patients., PMID:39499758
Elucidating the role of PPARG inhibition in enhancing MERS virus immune response: A network pharmacology and computational drug discovery., PMID:39437592
Evidence for a sex-dependent effect modification in the association between IFN-λ DNA polymorphisms and expression of IFN-λ and interferon-stimulated genes in human PBMCs., PMID:39423653
The Versatile Roles of nc886, a Fascinating and Peculiar Regulatory Non-Coding RNA, in Cancer., PMID:39409154
Identification and RT-qPCR Validation of Biomarkers Based on Butyrate Metabolism-Related Genes to Predict Recurrent Miscarriage., PMID:39372587
Prognostic value and molecular mechanisms of OAS1 in lung adenocarcinoma., PMID:39334033
Kinetic and Mechanistic Studies of Human Oligoadenylate Synthetase 1., PMID:39319583
Genetic variants regulating the immune response improve the prediction of COVID-19 severity provided by clinical variables., PMID:39237611
Evaluation of Laser Intensity Effect on Photodynamic Therapy Efficacy., PMID:39193105
Response of bovine endometrium to interferon tau in the presence of lipopolysaccharide., PMID:39180888
A non-canonical function of OAS1 to combat viral and bacterial infections., PMID:39142270
Proliferative arrest induces neuronal differentiation and innate immune responses in normal and Creutzfeldt-Jakob Disease agent (CJ) infected rat septal neurons., PMID:39131355
Using exploratory pharmacokinetic and pharmacodynamic analyses to predict the probability of flu-like symptoms in healthy volunteers and patients with chronic hepatitis B treated with the toll-like receptor 7 agonist ruzotolimod., PMID:39119977
RNA helicase SKIV2L limits antiviral defense and autoinflammation elicited by the OAS-RNase L pathway., PMID:39112803
Viral interference between severe acute respiratory syndrome coronavirus 2 and influenza A viruses., PMID:39038029
Type I interferon gene expression signature as a marker to predict response to cyclophosphamide based treatment in proliferative lupus nephritis., PMID:39033304
Human genetic and immunological determinants of SARS-CoV-2 infection and multisystem inflammatory syndrome in children., PMID:39028583
Potential Mechanism and Therapeutic Targets of Polymyositis., PMID:38978245
A comparative analysis of RNA-Seq and NanoString technologies in deciphering viral infection response in upper airway lung organoids., PMID:38957806
The canonical antiviral protein oligoadenylate synthetase 1 elicits antibacterial functions by enhancing IRF1 translation., PMID:38955184
Functional Analysis of Oligoadenylate Synthetase in the Emu (Dromaius novaehollandiae)., PMID:38891626
For research use only. Not for human or drug use.
