Catalog No.
YHB87101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser2-Ile417
Predicted molecular weight
46.79 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P00558
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PRP 2, Primer recognition protein 2, PGKA, PGK1, Phosphoglycerate kinase 1, Cell migration-inducing gene 10 protein
PGK1 phosphorylates NLRP3 and mediates inflammasome activation independent of its glycolytic activity., PMID:40471786
Inhibition of Phosphoglycerate Kinase 1 Enhances Radiosensitivity of Esophageal Squamous Cell Carcinoma to X-rays and Carbon Ion Irradiation., PMID:40464515
Inhibition of NF-κB Signaling by the Reactive Glycolytic Metabolite Methylglyoxal., PMID:40463275
Selection and validation of reference genes for RT-qPCR normalization in dormant cancer cells., PMID:40450038
Corrigendum to "Identification of a novel non-ATP-competitive protein kinase inhibitor of PGK1 from marine nature products" [Biochem. Pharmacol. 183 (2021) 114343]., PMID:40381355
Esculetin inhibits liver cancer by targeting glucose-6-phosphate isomerase mediated glycolysis., PMID:40373632
Isochlorogenic Acid A Attenuated Periodontitis by Inhibiting Inflammation via ACE/PGK1/STAT1 Signaling., PMID:40368646
A versatile genetic toolkit for engineering Wickerhamomyces ciferrii for tetraacetyl phytosphingosine production., PMID:40357330
Artificial intelligence-assisted RNA-binding protein signature for prognostic stratification and therapeutic guidance in breast cancer., PMID:40308601
Mapping the Interactome of OSCC Prognostic-Associated Proteins NDRG1 and PGK1 Through Proximity Labeling Using TurboID., PMID:40304068
Vacuole and mitochondria patch protein Mcp1 of Saccharomyces boulardii impairs the oxidative stress response of Candida albicans by regulating 2-phenylethanol., PMID:40259315
Glycolysis-enhancing α1-adrenergic antagonists are neuroprotective in Alzheimer's disease., PMID:40236185
SIX1 enhances aerobic glycolysis and progression in cervical cancer through ENO1., PMID:40234326
Development of a breast cancer invasion score to predict tumor aggressiveness and prognosis via PI3K/AKT/mTOR pathway analysis., PMID:40204712
Research note: Reference genes selection for gene expression analyses in reproductive turkey (Meleagris gallopavo) with yellow semen syndrome., PMID:40187017
Heterogeneity of Neutrophils and Immunological Function in Neonatal Sepsis: Analysis of Molecular Subtypes Based on Hypoxia-Glycolysis-Lactylation., PMID:40177399
Annexin A2 binds the 3'-UTR of H2AX mRNA and regulates histone-H2AX-derived hypoxia-inducible factor 1-alpha activation., PMID:40164417
2,3,4-Trihydroxybenzophenone-induced cardiac and neurological toxicity: Heart-brain interaction mediated by regulation of pgam1a and pgk1 involved in glycolysis and gluconeogenesis in zebrafish., PMID:40157088
Circ_0022587 Regulates Tumor Properties of Human Breast Cancer Cells by Targeting miR-335-5p/Phosphoglycerate Kinase 1 Pathway., PMID:40096161
Proteogenomic characterization of molecular and cellular targets for treatment-resistant subtypes in locally advanced cervical cancers., PMID:40087745
DUSP4 inhibited tumor cell proliferation by downregulating glycolysis via p-ERK/p-PGK1 signaling in ovarian cancer., PMID:40082940
PGK1 enhances productive bovine herpesvirus 1 infection by stimulating β-catenin-dependent transcription., PMID:40055833
Esketamine attenuates traumatic brain injury by modulating STAT3-mediated Glycolysis and immune responses., PMID:40055623
Hsa_circ_0001756 drives gastric cancer glycolysis by increasing the expression and stability of PGK1 mRNA., PMID:40051638
Large-scale CRISPRi screens link metabolic stress to glioblastoma chemoresistance., PMID:40050992
Pan-cancer investigation regarding the prognostic predictive and immunological regulation functions of PGK1 and experimental validation in esophageal squamous cell carcinoma., PMID:40047969
First Report of Phosphoglycerate Kinase Deficiency in a Dinè Child With Review of Current Literature., PMID:40026287
Icariside II inhibits Epithelial-Mesenchymal transition in metastatic osteosarcoma by antagonizing the miR-194/215 cluster via PGK1., PMID:40023448
Anti-PGK1 antibodies in immuno-related pancytopenia., PMID:40008495
Targeting macrophage polarization by inhibiting Pim2 alleviates inflammatory arthritis via metabolic reprogramming., PMID:40000906
Identification of key genes related to unilateral cryptorchidism in sheep by comprehensive transcriptomics and proteomics analyses., PMID:39972276
Di-Dang-Tang suppresses ferroptosis in the hippocampal CA1 region by targeting PGK1/NRF2/GPX4 signaling pathway to exert neuroprotection in vascular dementia., PMID:39946772
HSP90 co-regulates the formation and nuclear distribution of the glycolytic output complex to promote resistance and poor prognosis in gastric cancer patients., PMID:39930487
Identification of biomarkers associated with macrophage polarization in diabetic cardiomyopathy based on bioinformatics and machine learning approaches., PMID:39914590
Oocyte transcriptomes and follicular fluid proteomics of ovine atretic follicles reveal the underlying mechanisms of oocyte degeneration., PMID:39893388
A cellular model of TDP-43 induces phosphorylated TDP-43 aggregation with distinct changes in solubility and autophagy dysregulation., PMID:39887552
Proteomics Reveals the Response Mechanism of Embryonic Bovine Lung Cells to Mycoplasma bovis Infection., PMID:39859536
Activation of mTOR/HK2 signaling mitigates effects of PYCR2 depletion in colorectal cells., PMID:39808866
From High Protection to Lethal Effect: Diverse Outcomes of Immunization Against Invasive Candidiasis with Different Candida albicans Extracellular Vesicles., PMID:39796100
A human induced pluripotent stem cell line, NIMHi016-A, established from fibroblasts of a neuromuscular disease patient carrying PGK1/p. Asn5Lys variant., PMID:39787833
Cucurbitacin E Glucoside as an Apoptosis Inducer in Melanoma Cancer Cells by Modulating AMPK/PGK1/PKM2 Pathway., PMID:39757677
The antiarthritic effect of CBR-470-1 in hypoxic environment is to increase the level of NOD-like receptor family pyrin domain containing 3 ubiquitination by decreasing phosphoglycerate kinase 1 activity., PMID:39731281
Effects of PGK1 on immunoinfiltration by integrated single-cell and bulk RNA-sequencing analysis in sepsis., PMID:39712033
ANGPTL4 mediated mesothelial-mesenchymal transition in pulmonary fibrosis: a potential therapeutic target., PMID:39707362
Downregulation of tRNA methyltransferase FTSJ1 by PM2.5 promotes glycolysis and malignancy of NSCLC via facilitating PGK1 expression and translation., PMID:39695074
Small Leucine Zipper Protein Regulates Glucose Metabolism of Prostate Cancer Cells via Induction of Phosphoglycerate Kinase 1., PMID:39594816
CSTF2 Supports Hypoxia Tolerance in Hepatocellular Carcinoma by Enabling m6A Modification Evasion of PGK1 to Enhance Glycolysis., PMID:39514400
SARS-CoV-2 and HSV-1 Induce Amyloid Aggregation in Human CSF Resulting in Drastic Soluble Protein Depletion., PMID:39510798
Design, Synthesis, and Molecular Docking of Quinazolines Bearing Caffeoyl Moiety for Targeting of PGK1/PKM2/STAT3 Signaling Pathway in the Human Breast Cancer., PMID:39506445
Screening and validating the optimal panel of housekeeping genes for 4T1 breast carcinoma and metastasis studies in mice., PMID:39488625
For research use only. Not for human or drug use.
