Catalog No.
EHB86901
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-Ser645
Predicted molecular weight
71.82 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P00533
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HER1, Receptor tyrosine-protein kinase erbB-1, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, EGFR, ERBB1, ERBB
Note
For research use only.
Mechanisms Underlying the Therapeutic Effects of Brucea javanica in Cervical Cancer Treatment Based on Network Pharmacology and Molecular Docking., PMID:40487864
SPDL1 inhibition enhances colorectal cancer progression via epidermal growth factor receptor/extracellular signal-regulated kinase pathways., PMID:40487946
An Advanced IVB Lung Adenocarcinoma Patient With KRAS Mutations, Benefited From Camrelizumab Combined With Anti-Angiogenic Agents for Therapy: A Case Report., PMID:40488279
Network pharmacology and molecular docking-based characterization of the mechanisms through which Astragali Radix-Atractylodes macrocephala Koidz herb pair can treat membranous nephropathy., PMID:40489804
Predictive power of tertiary lymphoid structure for prognosis and neoadjuvant chemotherapy response in HER2-positive breast cancer., PMID:40489875
Amiloride synergizes with EGFR PROTACs and inhibitors to overcome therapeutic resistance in NSCLC., PMID:40489919
RalGAP complexes control secretion and primary cilia in pancreatic disease., PMID:40490362
Association Between the Hemoglobin Glycation Index (HGI) and Risk of Diabetic Nephropathy: A Retrospective Cohort Study., PMID:40491573
Impaired lung function is associated with elevated blood biomarkers of AD/ADRD: Unraveling the interplay with risk of dementia., PMID:40492085
Supramolecular Host-Guest Assemblies for Tunable and Modular Lysosome-Targeting Protein Degradation., PMID:40492932
Prevalence and risk factors of chronic kidney disease of unknown etiology in Northeast Thailand., PMID:40493280
Biomarker-Specific Survival and Medication Cost for Patients With Non-Small Cell Lung Cancer., PMID:40493365
Redundancy of the OST catalytic subunit facilitates therapeutic targeting of N-glycosylation., PMID:40494352
Dose-dependent immunotoxic mechanisms of celastrol via modulation of the PI3K-Akt signaling pathway., PMID:40495892
Targeting the Cargo Receptor TMED9 as a Therapeutic Strategy Against Brain Tumors., PMID:40497947
ERBB2-Low Expression by Race and Ethnicity Among Patients With Triple-Negative Breast Cancer., PMID:40498483
Postoperative 20% Albumin Infusion and Acute Kidney Injury in High-Risk Cardiac Surgery Patients: The ALBICS AKI Randomized Clinical Trial., PMID:40498523
Dynamic VOC fingerprinting and mechanistic exploration of medicinal edible fungus Inonotus hispidus: A combination of HS-GC-IMS/MS multivariate analysis and network-based pharmacology., PMID:40499502
Super-resolution microscopy reveals alterations in clathrin structure in human cancer tissue., PMID:40499781
Exploring the Mechanism of Feiyanning formula and its extract Apigenin Against EGFR-TKIs Resistance in Non-Small Cell Lung cancer Based on UPLC-HRMS and Experimental Validation., PMID:40499802
Impact of age and comorbidities on real-world outcomes in advanced breast cancer patients treated with palbociclib in first line: a nation-wide Danish retrospective study., PMID:40500959
Kasugamycin inhibits melanoma lung metastasis and regulates CHI3L1-driven M2-like tumor-associated macrophage differentiation., PMID:40501604
Modeling acquired TKI resistance and effective combination therapeutic strategies in murine RET+ lung adenocarcinoma., PMID:40502048
RNF213-Dependent EGFR and HER2 Activation Regulates Specific Downstream Signaling Pathways in Human Cancer Cells., PMID:40503863
Hereditary breast cancer beyond BRCA: clinicopathological characteristics and long-term outcomes., PMID:40504267
YiQiChuTan formula (YQCTF) inhibit the progression of non-small cell lung cancer via down-regulating EGFR/ITGB2 signaling: Triangulated evidence from network pharmacology, proteomic profiling, and experimental validation., PMID:40505482
CYR61 and CTGF mediate the stimulatory effect of amphiregulin on COX-2 expression in human granulosa-lutein cells., PMID:40506006
Therapeutic Outcomes of Osimertinib in EGFR - Mutant Non-Small Cell Lung Cancer With Brain Metastases: Results From a Retrospective Study at Vietnam National Cancer Hospital., PMID:40506044
[Research Status and Progress of Third-generation EGFR-TKIs
in Elderly Patients with Non-small Cell Lung Cancer]., PMID:40506487
Covalent Recruitment of NEDD4 for Targeted Protein Degradation: Rational Design of Small Molecular Degraders., PMID:40506832
Reciprocal Fluctuations in Lipoprotein Lipase, Glycosylphosphatidylinositol-Anchored High-Density Lipoprotein-Binding Protein 1, and Hepatic Triglyceride Lipase Levels in the Peripheral Bloodstream Are Correlated with Insulin Resistance., PMID:40507147
Evaluation of Risk Factors for Kidney Function Decline and Chronic Kidney Disease in Living Kidney Donors., PMID:40507639
Dihydrocapsaicin Enhances Tumor Necrosis Factor-α-Induced Apoptosis and G1 Cell Cycle Arrest in Human Cervical Cancer Cells Through TAK1-Mediated NF-κB and EGFR Pathways., PMID:40507823
Unraveling Botulinum Neurotoxin A Light-Chain-Induced Signaling Pathways: A Phosphoproteomic Analysis in a Controlled Cellular Model., PMID:40507977
Potassium Iodide Induces Apoptosis in Salivary Gland Cancer Cells., PMID:40508009
Knockdown of Claudin-8 (CLDN8) Indicates a Link Between Breast Cancer Cell Sensitivity to Chemotherapeutics and Reveals a Potential Use of CLDN8 as a Molecular Diagnostic and Target for Therapy., PMID:40508219
Potential supplementary tumor markers for liquid biopsy in non-small cell lung cancer., PMID:40510243
Association between physiological serum total bilirubin concentrations and the progression of diabetic nephropathy., PMID:40510475
Inverse association between remnant cholesterol and risks of atrial fibrillation among patients with type 2 diabetes., PMID:40510480
Cardiovascular and Thromboembolic Events in Children and Adults With Glomerular Disease: Findings From the Cure GlomeruloNephropathy (CureGN) Network., PMID:40510608
Variations in Creatinine Generation Among Patients With Glomerular Disease: Evidence From the NEPTUNE and CureGN Studies., PMID:40510610
LiGeR-HN phase III trials of petosemtamab + pembrolizumab and petosemtamab monotherapy in recurrent or metastatic HNSCC., PMID:40511820
Prognostic impact of HER2-low expression in triple-negative breast cancer of high-grade special histological type and no special type., PMID:40512776
Structural insights into the activation and inhibition of the ADAM17-iRhom2 complex., PMID:40512800
Impact of Renal Impairment on the Pharmacodynamic and Pharmacokinetic Profiles of Epaminurad, a Novel Uric Acid Transporter 1 Inhibitor., PMID:40513003
Development and Validation of a Knowledge, Attitude, and Practice (KAP) Questionnaire and its utility study towards Nutritional Habits among Non-Dialytic CKD Patients: A Prospective Study., PMID:40513844
Resolving spatial subclonal genomic heterogeneity of loss of heterozygosity and extrachromosomal DNA in gliomas., PMID:40514380
Association of HER2-low with clinicopathological features in patients with early invasive lobular breast cancer: an international multicentric study., PMID:40514709
MiR-106b-5p improving the progression of chronic kidney disease by inhibiting the TGF-β/Smad pathway., PMID:40514734
Silencing IFIT3 suppresses the EGFR/VEGF pathway and modulates SOCS1 to attenuate skin fibrosis in systemic sclerosis., PMID:40515878
For research use only. Not for human or drug use.
