Catalog No.
YHB85901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly103-Thr427
Predicted molecular weight
39.86 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P00439
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PAH, Phe-4-monooxygenase, Phenylalanine-4-hydroxylase
Pulmonary arterial hypertension in systemic lupus erythematosus: identification of risk factors and haemodynamics characteristics in a multicentre retrospective cohort., PMID:40514051
CTRP7 as a molecular biomarker associating with responsiveness to pulmonary vasodilators: insights from human and animal studies in pulmonary arterial hypertension., PMID:40504501
Case Report: Pulmonary arterial hypertension in children caused by a new mutation in the BMPR2 gene., PMID:40496024
Deficient FANCL Predisposes Endothelial Damage: A New Therapeutic Target for Pulmonary Hypertension., PMID:40479584
Genomic profiling, implications for genotype-based treatment of 131 patients with phenylketonuria and characterization of novel p.Pro416Leu PAH variant., PMID:40473815
Mechanism of ferroptosis in hypoxia-induced pulmonary vascular remodeling in hypoxia pulmonary hypertension: a study based on the ACE2-Ang-(1-7)-Mas axis., PMID:40466901
Roles of Pyruvate Kinase M2 in Pulmonary Diseases: What Do We Know So Far?, PMID:40464996
Baseline oxidative stress responses and cytochrome P450 gene expression in Tympanotonos fuscatus from PAH-contaminated ecosystem in the Niger Delta, Nigeria., PMID:40455302
Exploratory Study of Prognostic Plasma Biomarkers in Patients with Pulmonary Arterial Hypertension., PMID:40451321
Targeted delivery of apelin using a novel extracellular vesicle platform for pulmonary arterial hypertension treatment., PMID:40449081
Down-regulation of serum SIRT6 levels is associated with an increased risk of chronic intestinal inflammation in children exposed to airborne particulate matter and polycyclic aromatic hydrocarbons from e-waste., PMID:40449062
CHD1L in cancer and beyond: structure, oncogenic functions, and therapeutic potential., PMID:40442742
TCF7 enhances pulmonary hypertension by boosting stressed natural killer cells and their interaction with pulmonary arterial smooth muscle cells., PMID:40442690
Integrating network pharmacology, quantitative transcriptomic analysis, and experimental validation revealed the mechanism of cordycepin in the treatment of obesity., PMID:40438591
Sotatercept: A Crosstalk Between Pathways and Activities in the Pulmonary Circulation and Blood., PMID:40429991
Polycyclic aromatic hydrocarbons are associated with sleep-related disorders in adults: the potential mediating role of inflammation., PMID:40420257
First nomogram for predicting interstitial lung disease and pulmonary arterial hypertension in SLE: a machine learning approach., PMID:40413556
Single-Cell and Spatial Transcriptomics Identified Fatty Acid-Binding Proteins Controlling Endothelial Glycolytic and Arterial Programming in Pulmonary Hypertension., PMID:40401371
[Progress in the metabolic and biotransformation of polycyclic aromatic hydrocarbons and their derivatives in humans]., PMID:40394737
Selective JAK-1 inhibitor Upadacitinib and peptide PD29 modulate the JAK and TGF-β/Smad signaling pathways reducing experimental dermal fibrosis., PMID:40381666
Lactobacillus Restructures the Micro/Mycobiome to Combat Inflammation-Mediated Right Ventricular Dysfunction in Pulmonary Arterial Hypertension., PMID:40376801
USP11 Promotes Endothelial Apoptosis-Resistance in Pulmonary Arterial Hypertension by Deubiquitinating HINT3., PMID:40376595
Dissecting Autophagy Gene Expression in Endothelial Cells of Pulmonary Arterial Hypertension at Single-Cell Resolution., PMID:40370624
Impact of cardiosphere-derived cells on the maladapted right ventricular muscle in a rat sugen/hypoxia model of pulmonary hypertension with right ventricular dysfunction., PMID:40354360
Cyclopamine Attenuates Pulmonary Arterial Hypertension Development: Implications of Hedgehog Signaling Involvement for the Pathophysiology., PMID:40353829
Gender difference in pre-clinical liver-directed gene therapy with lentiviral vectors., PMID:40351478
Mechanotransductive stabilization of HIF-1α is inhibited by mitochondrial antioxidant therapy in the setting of pulmonary overcirculation., PMID:40348934
McFerritin cooperates with McNrf2 to attenuate benzo[a]pyrene-induced oxidative stress in the thick-shell mussel Mytilus coruscus., PMID:40348216
Exposure to polycyclic aromatic hydrocarbons and risk of abnormal liver function: The mediating role of C-reactive protein., PMID:40347725
Knockdown of eIF3a alleviates pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition via TGFβ1/SMAD pathway., PMID:40346622
Environmental Aromatic Amine Induces Pulmonary Arterial Hypertension Associated With Estrogen Signaling and Serpine1., PMID:40344275
Anthocyanin attenuates pulmonary arterial hypertension and associated heart failure via improving mitochondrial function through Nrf2-dependent mechanism., PMID:40343792
Drugs targeting novel pathways in pulmonary arterial hypertension., PMID:40341051
Store-operated Ca2+ entry is involved in endothelium-to-mesenchymal transition in lung vascular endothelial cells., PMID:40331589
Activin-A Regulates Bone Morphogenetic Protein Signaling in Pulmonary Endothelial Cells Without Affecting Bone Morphogenetic Protein Type-II Receptor Expression., PMID:40330556
Combination therapy of GnRHa, RhGH and anastrozole to improve final adult height deficit in CAH children with CPP., PMID:40329244
In Situ Encapsulation of Organophosphorus Hydrolase into a Reduction-Catalytic Cu-MOF for Chemoenzymatic Cascade Conversion of Methyl Parathion to 4-Aminophenol., PMID:40326991
Fasting and postprandial kidney haemodynamic effects of empagliflozin and linagliptin in mono- and combination therapy compared to gliclazide in overweight people with type 2 diabetes (RACELINES): A randomised, double-blind trial., PMID:40326063
A cost-effective vessel-on-a-chip for high shear stress applications in vascular biology., PMID:40324629
Efficacy of first-year GnRHa therapy in girls with idiopathic central precocious puberty diagnosed after age 8: a retrospective study., PMID:40323240
A robust high-capacity gelatin/polyethyleneimine/poly (allylamine hydrochloride) biosorbent for uranium extraction in aqueous solution., PMID:40316093
Establishment of a lupus-prone mouse model of pulmonary arterial hypertension with intermittent hypoxia: functional, biochemical and histological verifications., PMID:40314184
Female Fibroblast Activation Is Estrogen-Mediated in Sex-Specific 3D-Bioprinted Pulmonary Artery Adventitia Models., PMID:40285704
Effects of Benzo[k]fluoranthene at Two Temperatures on Viability, Structure, and Detoxification-Related Genes in Rainbow Trout RTL-W1 Cell Spheroids., PMID:40278618
Tet Methylcytosine Dioxygenase 2 (TET2) Mutation Drives a Global Hypermethylation Signature in Patients With Pulmonary Arterial Hypertension (PAH): Correlation With Altered Gene Expression Relevant to a Common T Cell Phenotype., PMID:40274312
Loss of ALDH2 accelerates the progression of pulmonary arterial hypertension through the 4-HNE/ERK1/2-p16INK4a signaling pathway., PMID:40274079
Sepiapterin for the treatment of phenylketonuria., PMID:40272408
Effect of incorporation strategies of sesamol and chitosan nanoparticle-methylcellulose edible coating on the polycyclic aromatic hydrocarbon levels in deep-fried meatballs., PMID:40263845
Childhood exposure to polycyclic aromatic hydrocarbons (PAHs) and cardiometabolic indicators in childhood and adolescence: findings from a cohort study in rural Bangladesh., PMID:40254235
Multi-omics analysis of two rat models reveals potential role of vesicle transport and autophagy in right ventricular remodeling., PMID:40251385
For research use only. Not for human or drug use.
