Catalog No.
YHB85101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ser501
Predicted molecular weight
57.17 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P00352
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Aldehyde dehydrogenase, cytosolic, Retinal dehydrogenase 1, ALDH-E1, RalDH1, Aldehyde dehydrogenase family 1 member A1, ALDH1A1, ALDH1, RALDH 1, ALDC, ALHDII, PUMB1
A Biological-Systems-Based Analyses Using Proteomic and Metabolic Network Inference Reveals Mechanistic Insights into Hepatic Lipid Accumulation: An IMI-DIRECT Study., PMID:40502600
Gene expression study in the siRNA based aniridia cell model and in primary aniridia limbal epithelial cells following duloxetine and ritanserin treatment., PMID:40493651
TGF-β Enhances Doxorubicin Resistance and Anchorage-Independent Growth in Cancer Cells by Inducing ALDH1A1 Expression., PMID:40414259
Molecular Determinants of A9 Dopaminergic Neurons., PMID:40397062
In-silico discovery of type-2 diabetes-causing host key genes that are associated with the complexity of monkeypox and repurposing common drugs., PMID:40370100
Breast Cancer Stem Cells and Immunogenicity Profile in High-Risk Early Triple-Negative Breast Cancer: A Pilot Study., PMID:40362201
(-)-Epicatechin regulates the resistance of lung adenocarcinoma cells to radiotherapy through the downregulation of FOXM1., PMID:40335843
Substituents introduction of methyl and methoxy functional groups on resveratrol stabilizes mTOR binding for autophagic cell death induction., PMID:40287470
Asymmetric cell division of ALDH1-positive cancer stem cells generates glycolytic metabolically diverse cell populations., PMID:40263471
Associations of circulating insulin-like growth factor-1 and insulin-like growth factor binding protein-3 with the expression of stem cell markers in benign breast tissue., PMID:40197284
Genetic variants associated with idiopathic Parkinson's disease in Latin America: A systematic review., PMID:40178685
Blood-based detection of MMP11 as a marker of prostate cancer progression regulated by the ALDH1A1-TGF-β1 signaling mechanism., PMID:40122809
Molecularly distinct striatonigral neuron subtypes differentially regulate locomotion., PMID:40108161
Integration of scRNA-seq and bulk RNA-seq to reveal the association and potential molecular mechanisms of metabolic reprogramming regulated by lactylation and chemotherapy resistance in ovarian cancer., PMID:40093000
CRISPR/Cas9 Targeting of Aldehyde Dehydrogenase 1A1 Reveals Heterogeneous Roles in Radiation Response and Redox Stress Across Clonal Lines in Triple-Negative Breast Cancer., PMID:40076923
Disruption of the sorcin‒PAX5 protein‒protein interaction induces ferroptosis by promoting the FBXL12-mediated ubiquitination of ALDH1A1 in pancreatic cancer., PMID:40055736
BIN1 inhibited tumor growth, metastasis and stemness by ALDH1/NOTCH pathway in bladder carcinoma., PMID:40016843
IL-8-NF-κB-ALDH1A1 loop promotes the progression of intrahepatic cholangiocarcinoma., PMID:40008905
Development and synthesis of diffractaic acid analogs as potent inhibitors of colorectal cancer stem cell traits., PMID:40000756
Aortic Valve Calcification Is Induced by the Loss of ALDH1A1 and Can Be Prevented by Agonists of Retinoic Acid Receptor Alpha: Preclinical Evidence for Drug Repositioning., PMID:39989358
Polyhexamethylene guanidine phosphate induces epithelial-to-mesenchymal transition and cancer stem cell-like properties via Wnt/β-catenin signaling in human bronchial epithelial cells., PMID:39986058
Activity-based sensing reveals elevated labile copper promotes liver aging via hepatic ALDH1A1 depletion., PMID:39979263
Long non-coding RNA H19 promotes cervical cancer development via targeting the microRNA-140/ALDH1A1 axis., PMID:39940029
Aldh1l1-Cre/ERT2 Drives Flox-Mediated Recombination in Peripheral and CNS Infiltrating Immune Cells in Addition to Astrocytes During CNS Autoimmune Disease., PMID:39910805
Predicting the hub interactome of COVID-19 and oral squamous cell carcinoma: uncovering ALDH-mediated Wnt/β-catenin pathway activation via salivary inflammatory proteins., PMID:39901050
Ferroptosis- and stemness inhibition-mediated therapeutic potency of ferrous oxide nanoparticles-diethyldithiocarbamate using a co-spheroid 3D model of pancreatic cancer., PMID:39888413
Multiplex single-cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer., PMID:39888143
Targeting AXL Inhibits the Growth and Metastasis of Prostate Cancer in Bone., PMID:39879384
Lobaric acid suppresses the stemness potential of colorectal cancer cells through mTOR/AKT., PMID:39874220
Establishment and evaluation of rabbit model for corneal ectasia by photorefractive keratectomy., PMID:39862961
Integrated metabolomics and mass spectrometry imaging analysis reveal the efficacy and mechanism of Huangkui capsule on type 2 diabetic nephropathy., PMID:39862790
SIRT2 and ALDH1A1 as critical enzymes for astrocytic GABA production in Alzheimer's disease., PMID:39815261
Silencing of Epidermal Growth Factor-like Domain 8 Promotes Proliferation and Cancer Aggressiveness in Human Ovarian Cancer Cells by Activating ERK/MAPK Signaling Cascades., PMID:39796130
The Significance of Aldehyde Dehydrogenase 1 in Cancers., PMID:39796106
Serum exosome-derived ALDH1A1 can greatly predict the prognosis of patients with hepatitis E virus-related acute liver failure., PMID:39753426
ALDH Enzymes and Hematological Diseases: A Scoping Review of Literature., PMID:39726306
Serum proteome profiling of plateau acclimatization in men using Olink proteomics approach., PMID:39725655
Aldehyde dehydrogenases as drug targets for cancer: SAR and structural biology aspects for inhibitor design., PMID:39689509
Bevacizumab increases cisplatin efficacy by inhibiting epithelial-mesenchymal transition via ALDH1 in cervical carcinoma., PMID:39662269
Targeting cancer stem cells by TPA leads to inhibition of refractory sarcoma and extended overall survival., PMID:39640862
Embryoid body-based differentiation of human-induced pluripotent stem cells into cells with a corneal stromal keratocyte phenotype., PMID:39613390
Aldehyde Dehydrogenase-1A1 (ALDH1A1): The Novel Regulator of Chemoresistance in Pancreatic Cancer Cells., PMID:39611960
Mechanism of Apigenin against breast cancer stem cells: network pharmacology and experimental validation., PMID:39605916
Redox-sensitive epigenetic activation of SUV39H1 contributes to liver ischemia-reperfusion injury., PMID:39603205
Rutin-Activated Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Attenuates Corneal and Heart Damage in Mice., PMID:39598433
Sox6 and ALDH1A1 Truncation by Asparagine Endopeptidase Defines Selective Neuronal Vulnerability in Parkinson's Disease., PMID:39573918
Ginsenoside Rg3 attenuates the stemness of breast cancer stem cells by activating the hippo signaling pathway., PMID:39561883
Weight loss and metabolic effects of an ALDH1A1-specific inhibitor, FSI-TN42, in a diet induced mouse model of obesity., PMID:39528599
Investigating the biology of microRNA links to ALDH1A1 reveals candidates for preclinical testing in acute myeloid leukemia., PMID:39513593
Structure-Based identification of a potent KDM7A inhibitor exerts anticancer activity through transcriptionally reducing MKRN1 in taxol- resistant and -sensitive triple-negative breast cancer cells., PMID:39509788
For research use only. Not for human or drug use.
