Catalog No.
YHB80301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Pro494
Predicted molecular weight
54.37 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>80% as determined by SDS-PAGE.
Accession
O95965
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
OSCP, Ten integrin EGF-like repeat domain-containing protein, ITGBL1, Integrin beta-like protein 1, Osteoblast-specific cysteine-rich protein, TIED
HBV activates hepatic stellate cells through RUNX2/ITGBL1 axis., PMID:40287769
Integrated analysis of bioinformatics, mendelian randomization, and experimental validation reveals novel diagnostic and therapeutic targets for osteoarthritis: progesterone as a potential therapeutic agent., PMID:39849508
m6A Methylation Regulator RBM15-Mediated Upregulation of ITGBL1 mRNA Stability Aggravates Colon Adenocarcinoma Progression by Remodeling the Tumor Microenvironment., PMID:39840822
Novel integrated multiomics analysis reveals a key role for integrin beta-like 1 in wound scarring., PMID:39558136
Integrin beta-like 1 is regulated by DNA methylation and increased in heart failure patients., PMID:39233619
Comprehensive meta-analysis reveals distinct gene expression signatures of MASLD progression., PMID:38565287
ITGBL1 promotes anoikis resistance and metastasis in human gastric cancer via the AKT/FBLN2 axis., PMID:38332530
Integrin beta-like 1 mediates fibroblast-cardiomyocyte crosstalk to promote cardiac fibrosis and hypertrophy., PMID:37395147
Characterization of candidate factors associated with the metastasis and progression of high-grade serous ovarian cancer., PMID:37284741
Single-cell RNA sequencing reveals that HSD17B2 in cancer-associated fibroblasts promotes the development and progression of castration-resistant prostate cancer., PMID:37244445
Mechanical pressure-induced dedifferentiation of myofibroblasts inhibits scarring via SMYD3/ITGBL1 signaling., PMID:37192621
Glypican-4 regulated actin cytoskeletal reorganization in glucocorticoid treated trabecular meshwork cells and involvement of Wnt/PCP signaling., PMID:36727620
Weighted Gene Co-Expression Network Analysis of Immune Infiltration in Nonalcoholic Fatty Liver Disease., PMID:36503447
Analysis of Fibroblast Growth Factor 14 (FGF14) structural variants reveals the genetic basis of the early onset nystagmus locus NYS4 and variable ataxia., PMID:36207621
Integrin subunit β-like 1 mediates angiotensin II-induced myocardial fibrosis by regulating the forkhead box Q1/Snail axis., PMID:36183845
Identification of HBEGF+ fibroblasts in the remission of rheumatoid arthritis by integrating single-cell RNA sequencing datasets and bulk RNA sequencing datasets., PMID:36068607
Nomogram Models Based on the Gene Expression in Prediction of Breast Cancer Bone Metastasis., PMID:36046013
Small extracellular vesicles derived from dermal fibroblasts promote fibroblast activity and skin development through carrying miR-218 and ITGBL1., PMID:35733144
A comprehensive analysis of potential gastric cancer prognostic biomarker ITGBL1 associated with immune infiltration and epithelial-mesenchymal transition., PMID:35596183
ITGBL1 transcriptionally inhibited by JDP2 promotes the development of pancreatic cancer through the TGF-beta/Smad pathway., PMID:35584452
Multi-staged gene expression profiling reveals potential genes and the critical pathways in kidney cancer., PMID:35508649
Jianpi Jiedu Recipe inhibits colorectal cancer liver metastasis via regulating ITGBL1-rich extracellular vesicles mediated activation of cancer-associated fibroblasts., PMID:35381565
Integrin β-like 1 protein (ITGBL1) promotes cell migration by preferentially inhibiting integrin-ECM binding at the trailing edge., PMID:35066808
Immune Checkpoints in Cancers: From Signaling to the Clinic., PMID:34572799
Screening differentially expressed genes between endometriosis and ovarian cancer to find new biomarkers for endometriosis., PMID:34409913
ITGBL1 is a new immunomodulator that favors development of melanoma tumors by inhibiting natural killer cells cytotoxicity., PMID:33413419
ITGBL1 promotes gastric cancer cell proliferation and invasion via Akt signal pathway., PMID:33049688
Evaluation of the Role of ITGBL1 in Ovarian Cancer., PMID:32961775
ITGBL1 promotes cell migration and invasion through stimulating the TGF-β signalling pathway in hepatocellular carcinoma., PMID:32537856
Role of the TLR4-androgen receptor axis and genistein in taxol-resistant ovarian cancer cells., PMID:32278794
Regulatory Mechanism of ITGBL1 in the Metastasis of Colorectal Cancer., PMID:32211321
Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation., PMID:32139701
Broader phenotypic traits and widespread brain hypometabolism in spinocerebellar ataxia 27., PMID:32112487
Upregulation of ITGBL1 predicts poor prognosis and promotes chemoresistance in ovarian cancer., PMID:31683459
Identification of differentially expressed genes and preliminary validations in cardiac pathological remodeling induced by transverse aortic constriction., PMID:31364721
Transcriptomic expression profiling identifies ITGBL1, an epithelial to mesenchymal transition (EMT)-associated gene, is a promising recurrence prediction biomarker in colorectal cancer., PMID:30717807
lncITPF Promotes Pulmonary Fibrosis by Targeting hnRNP-L Depending on Its Host Gene ITGBL1., PMID:30528088
Inhibit integrins to protect cartilage., PMID:30390042
Hypermethylation of ITGBL1 is associated with poor prognosis in acute myeloid leukemia., PMID:30317626
ITGBL1 modulates integrin activity to promote cartilage formation and protect against arthritis., PMID:30305454
Identification of Potential Key Genes Associated With the Pathogenesis and Prognosis of Gastric Cancer Based on Integrated Bioinformatics Analysis., PMID:30065754
Prednisolone induces osteoporosis-like phenotypes via focal adhesion signaling pathway in zebrafish larvae., PMID:30012552
ITGBL1 promotes migration, invasion and predicts a poor prognosis in colorectal cancer., PMID:29772438
miR-199a-3p enhances cisplatin sensitivity of ovarian cancer cells by targeting ITGB8., PMID:29436681
ITGBL1 Predicts a Poor Prognosis and Correlates EMT Phenotype in Gastric Cancer., PMID:29151964
Characterization of gene expression profiles in HBV-related liver fibrosis patients and identification of ITGBL1 as a key regulator of fibrogenesis., PMID:28262670
Extracellular matrix protein ITGBL1 promotes ovarian cancer cell migration and adhesion through Wnt/PCP signaling and FAK/SRC pathway., PMID:27261588
Epigenetic downregulated ITGBL1 promotes non-small cell lung cancer cell invasion through Wnt/PCP signaling., PMID:26307393
ITGBL1 Is a Runx2 Transcriptional Target and Promotes Breast Cancer Bone Metastasis by Activating the TGFβ Signaling Pathway., PMID:26060017
Transcriptome analysis of the human corneal endothelium., PMID:25377225
For research use only. Not for human or drug use.
