Catalog No.
YHB71901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln579-Asp1058
Predicted molecular weight
80.24 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95696
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Bromodomain and PHD finger-containing protein 2, BRPF2, BR140-like protein, BRL, BRD1, Bromodomain-containing protein 1
A screen of chromatin-targeting compounds identifies TAF1 as a novel regulator of HIV latency., PMID:40475469
CD4+ tissue-resident memory Th17 cells are a major source of IL-17A in Spondyloarthritis synovial tissue., PMID:40413112
BRD1 deficiency affects SREBF1-related lipid metabolism through regulating H3K9ac/H3K9me3 transition to inhibit HCC progression., PMID:39962068
NIT2 dampens BRD1 phase separation and restrains oxidative phosphorylation to enhance chemosensitivity in gastric cancer., PMID:39565874
BLA1 Affects Leaf Angles by Altering Brassinosteroid Biosynthesis in Rice (Oryza sativa L.)., PMID:39207175
The effect of overexpression of CyPA on gene expression in human umbilical vein endothelial cells., PMID:39029007
Structural basis for double-stranded RNA recognition by SID1., PMID:38742627
Evidence for common mechanisms of pathology between SHANK3 and other genes of Phelan-McDermid syndrome., PMID:38414139
The ORFIUS complex regulates ORC2 localization at replication origins., PMID:38288445
Panel-based RNA fusion sequencing improves diagnostics of pediatric acute myeloid leukemia., PMID:38086945
Brain Gene Co-Expression Network Analysis Identifies 22q13 Region Genes Associated with Autism, Intellectual Disability, Seizures, Language Impairment, and Hypotonia., PMID:38002941
Analysis of Communal Molecular Mechanism Between Chronic Obstructive Pulmonary Disease and Osteoporosis., PMID:36937804
BRM Complex in Arabidopsis Adopts ncBAF-like Composition and Requires BRD Subunits for Assembly and Stability., PMID:36835328
A t(4;13)(q21;q14) translocation in B-cell chronic lymphocytic leukemia causing concomitant homozygous DLEU2/miR15a/miR16-1 and heterozygous ARHGAP24 deletions., PMID:36641997
Bioinformatics-based analysis of potential candidates chromatin regulators for immune infiltration in osteoarthritis., PMID:36550476
A Therapeutically Targetable NOTCH1-SIRT1-KAT7 Axis in T-cell Leukemia., PMID:36322781
Conservation of transcriptional regulation by BRCA1 and BARD1 in Caenorhabditis elegans., PMID:36250637
Hydrophobic cavity-directed azide-acetyllysine photochemistry for profiling non-histone interacting partners of bromodomain protein 1., PMID:35975005
The psychiatric risk gene BRD1 modulates mitochondrial bioenergetics by transcriptional regulation., PMID:35941107
Phenotypic Variability in Phelan-McDermid Syndrome and Its Putative Link to Environmental Factors., PMID:35328081
Expression Characteristics and Clinical Correlations of BRD1 in Colorectal Cancer Samples., PMID:34482774
Bromodomain-containing subunits BRD1, BRD2, and BRD13 are required for proper functioning of SWI/SNF complexes in Arabidopsis., PMID:34327319
HBO1 is a versatile histone acyltransferase critical for promoter histone acylations., PMID:34259319
Are BET Inhibitors yet Promising Latency-Reversing Agents for HIV-1 Reactivation in AIDS Therapy?, PMID:34072421
Inactivation of the Schizophrenia-associated BRD1 gene in Brain Causes Failure-to-thrive, Seizure Susceptibility and Abnormal Histone H3 Acetylation and N-tail Clipping., PMID:34056693
Bromodomain-containing proteins BRD1, BRD2, and BRD13 are core subunits of SWI/SNF complexes and vital for their genomic targeting in Arabidopsis., PMID:33771698
BRCA1-BARD1 Regulates Axon Regeneration in Concert with the Gqα-DAG Signaling Network., PMID:33593852
Crystal structure of the BRPF2 PWWP domain in complex with DNA reveals a different binding mode than the HDGF family of PWWP domains., PMID:33556623
Discovery of a hidden transient state in all bromodomain families., PMID:33468647
Acquired mutations and transcriptional remodeling in long-term estrogen-deprived locoregional breast cancer recurrences., PMID:33407744
Enhanced Efficacy of Simultaneous PD-1 and PD-L1 Immune Checkpoint Blockade in High-Grade Serous Ovarian Cancer., PMID:33158814
BRD4/8/9 are prognostic biomarkers and associated with immune infiltrates in hepatocellular carcinoma., PMID:32927435
Meiotic Double-Strand Break Processing and Crossover Patterning Are Regulated in a Sex-Specific Manner by BRCA1-BARD1 in Caenorhabditis elegans., PMID:32796008
Reduced Brd1 expression leads to reversible depression-like behaviors and gene-expression changes in female mice., PMID:32681022
BRCA1-associated structural variations are a consequence of polymerase theta-mediated end-joining., PMID:32680986
A Chemical Switch System to Modulate Chimeric Antigen Receptor T Cell Activity through Proteolysis-Targeting Chimaera Technology., PMID:32352759
Genome-wide association study identifies new loci for albuminuria in the Japanese population., PMID:32277301
An integrative, genomic, transcriptomic and network-assisted study to identify genes associated with human cleft lip with or without cleft palate., PMID:32241273
Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation., PMID:32193360
In silico design and molecular basis for the selectivity of Olinone toward the first over the second bromodomain of BRD4., PMID:31587361
Deciphering structure, function and mechanism of lysine acetyltransferase HBO1 in protein acetylation, transcription regulation, DNA replication and its oncogenic properties in cancer., PMID:31535175
Teosinte ligule allele narrows plant architecture and enhances high-density maize yields., PMID:31416957
A chemical toolbox for the study of bromodomains and epigenetic signaling., PMID:31015424
Brain proteome changes in female Brd1+/- mice unmask dendritic spine pathology and show enrichment for schizophrenia risk., PMID:30590179
Brain volumetric alterations accompanied with loss of striatal medium-sized spiny neurons and cortical parvalbumin expressing interneurons in Brd1+/- mice., PMID:30405140
The tumor suppressor BRCA1-BARD1 complex localizes to the synaptonemal complex and regulates recombination under meiotic dysfunction in Caenorhabditis elegans., PMID:30383767
BRCA1-BARD1 associate with the synaptonemal complex and pro-crossover factors and influence RAD-51 dynamics during Caenorhabditis elegans meiosis., PMID:30383754
Splicing and Chromatin Factors Jointly Regulate Epidermal Differentiation., PMID:30380419
Evaluating the bromodomain protein BRD1 as a therapeutic target in rheumatoid arthritis., PMID:30042400
No association of BRD1 and ZBED4 polymorphisms with schizophrenia in the Chinese Han population., PMID:29794561
For research use only. Not for human or drug use.
