Catalog No.
YHB70401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys126-Ser368
Predicted molecular weight
29.44 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95630
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Endosome-associated ubiquitin isopeptidase, STAM-binding protein, AMSH, Associated molecule with the SH3 domain of STAM, STAMBP
Mediators of the causal associations between protein ratios and ischemic stroke: a two-step Mendelian randomization study., PMID:40181221
Gut Escherichia coli promotes lung cancer by increasing circulating STAMBP production., PMID:40180620
Admission glucose, HbA1c levels and inflammatory cytokines in patients with acute ST-elevation myocardial infarction., PMID:39962379
Exploring lipidome mediated inflammatory pathways in acute pancreatitis using mendelian randomization., PMID:39774240
High cumulative glucocorticoid dose is associated with increased levels of inflammation-related mediators in active rheumatoid arthritis., PMID:39744635
Identification of STAM-binding protein as a target for the treatment of gemcitabine resistance pancreatic cancer in a nutrient-poor microenvironment., PMID:39242557
AAV-mediated Stambp gene replacement therapy rescues neurological defects in a mouse model of microcephaly-capillary malformation syndrome., PMID:39169623
Can Biomarkers Correctly Predict Ventilator-associated Pneumonia in Patients Treated With Targeted Temperature Management After Cardiac Arrest? An Exploratory Study of the Multicenter Randomized Antibiotic (ANTHARTIC) Study., PMID:38957212
STAMBP is Required for Long-Term Maintenance of Neural Progenitor Cells Derived from hESCs., PMID:38951308
Effects of circulating inflammatory proteins on spinal degenerative diseases: Evidence from genetic correlations and Mendelian randomization study., PMID:38895179
Exploratory study of blood biomarkers in patients with post-stroke epilepsy., PMID:38557165
Involvement of the OTUB1-YAP1 axis in driving malignant behaviors of head and neck squamous cell carcinoma., PMID:37986681
Proteomic profiling identifies novel inflammation-related plasma proteins associated with ischemic stroke outcome., PMID:37794467
Integrated proteomics and genomics analysis of paradoxical eczema in psoriasis patients treated with biologics., PMID:37536512
Identification of State Markers in Anorexia Nervosa: Replication and Extension of Inflammation Associated Biomarkers Using Multiplex Profiling in Anorexia Nervosa and Atypical Anorexia Nervosa., PMID:37461669
Olink proteomics profiling platform reveals non-invasive inflammatory related protein biomarkers in autism spectrum disorder., PMID:37293545
Inflammatory Blood Signature Related to Common Psychological Comorbidity in Chronic Pain., PMID:36979692
Mitochondrial DNA and inflammatory proteins are higher in extracellular vesicles from frail individuals., PMID:36710345
The deubiquitinating enzyme STAMBP is a newly discovered driver of triple-negative breast cancer progression that maintains RAI14 protein stability., PMID:36434041
Distinct inflammation-related proteins associated with T cell immune recovery during chronic HIV-1 infection., PMID:36408648
The expression and clinical significance of STAMBP in breast cancer., PMID:36309616
STAM binding protein regulated by hsa_circ_0007334 exerts oncogenic potential in pancreatic cancer., PMID:36089485
Novel compound heterozygous mutation in STAMBP causes a neurodevelopmental disorder by disrupting cortical proliferation., PMID:36033615
Association of extracellular vesicle inflammatory proteins and mortality., PMID:35982068
STAMBP gene mutation causing microcephaly-capillary malformation syndrome: a recognizable developmental and epileptic encephalopathy., PMID:35770778
Inflammation and Interferon Signatures in Peripheral B-Lymphocytes and Sera of Individuals With Fibromyalgia., PMID:35693781
Multi-staged gene expression profiling reveals potential genes and the critical pathways in kidney cancer., PMID:35508649
Structural and functional characterization of ubiquitin variant inhibitors for the JAMM-family deubiquitinases STAMBP and STAMBPL1., PMID:34425109
STAMBP promotes lung adenocarcinoma metastasis by regulating the EGFR/MAPK signaling pathway., PMID:34102455
The deubiquitinase STAMBP modulates cytokine secretion through the NLRP3 inflammasome., PMID:33253913
Agonist-activated glucagon receptors are deubiquitinated at early endosomes by two distinct deubiquitinases to facilitate Rab4a-dependent recycling., PMID:32967969
[Resistant epileptic encephalopathy in a child with microcephalic capillary malformation syndrome]., PMID:32929933
Profiling of Inflammatory Proteins in Plasma of HIV-1-Infected Children Receiving Antiretroviral Therapy., PMID:32906648
High-throughput screening of functional deubiquitinating enzymes in autophagy., PMID:32453962
Aberrant inflammatory profile in acute but not recovered anorexia nervosa., PMID:32389698
Regulation of Oncogenic Targets by miR-99a-3p (Passenger Strand of miR-99a-Duplex) in Head and Neck Squamous Cell Carcinoma., PMID:31795200
Multiplex proteomics identifies novel CSF and plasma biomarkers of early Alzheimer's disease., PMID:31694701
Prediagnostic circulating inflammation biomarkers and esophageal squamous cell carcinoma: A case-cohort study in Japan., PMID:31671219
Early‑onset epilepsy and microcephaly‑capillary malformation syndrome caused by a novel STAMBP mutation in a Chinese boy., PMID:31638258
STAM-binding protein regulates melanoma metastasis through SLUG stabilization., PMID:30454887
A novel homozygous missense mutation in the SH3-binding motif of STAMBP causing microcephaly-capillary malformation syndrome., PMID:29907875
Identification of differentially expressed genes regulated by molecular signature in breast cancer-associated fibroblasts by bioinformatics analysis., PMID:29063236
Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity., PMID:28492230
Inflammatory markers in late pregnancy in association with postpartum depression-A nested case-control study., PMID:28285186
Characterizing polyubiquitinated forms of the neurodegenerative ubiquitin mutant UBB+1., PMID:27861798
NMR Reveals the Interplay among the AMSH SH3 Binding Motif, STAM2, and Lys63-Linked Diubiquitin., PMID:27725184
Microcephaly-capillary malformation syndrome: Brothers with a homozygous STAMBP mutation, uncovered by exome sequencing., PMID:27531570
Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015) : Jeddah, Kingdom of Saudi Arabia. 30 November - 3 December 2015., PMID:27454254
The Vps27/Hrs/STAM (VHS) Domain of the Signal-transducing Adaptor Molecule (STAM) Directs Associated Molecule with the SH3 Domain of STAM (AMSH) Specificity to Longer Ubiquitin Chains and Dictates the Position of Cleavage., PMID:26601948
For research use only. Not for human or drug use.
