Catalog No.
YHB70001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly167-Ile385
Predicted molecular weight
25.62 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95622
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
AC5, ATP pyrophosphate-lyase 5, Adenylate cyclase type 5, Adenylate cyclase type V, Adenylyl cyclase 5, ADCY5
Identification of genetic signatures of positive selection in apes linked to life-history trait adaptations., PMID:40320481
Pearls & Oy-sters: ADCY5-Related Dyskinesia: From a Longstanding Misdiagnosis of Drug-Resistant Epilepsy., PMID:40300124
Treatment Efficacy of Theophylline in ADCY5-Related Dyskinesia: A Retrospective Case Series Study., PMID:40079709
ADCY5 Gene Affects Seasonal Reproduction in Dairy Goats by Regulating Ovarian Granulosa Cells Steroid Hormone Synthesis., PMID:40004085
Generation of an induced pluripotent stem cell line (UCLi026-A) from a patient with ADCY5-related disease carrying the heterozygous variant c.1253G > A; (p. Arg418Gln)., PMID:39919432
Atypical ADCY5-related movement disorders: Highlighting adolescent/adult-onset cervical dystonia., PMID:39908726
Gradient boosting reveals spatially diverse cholesterol gene signatures in colon cancer., PMID:39678375
Effect of food enrichment based on diverse feeding regimes on the immunity of Nibea albiflora by biochemical and RNA-seq analysis of the spleen., PMID:39580873
Use of Botulinum Toxin in Upper-Limb Tremor: Systematic Review and Perspectives., PMID:39330850
ADCY5 act as a putative tumor suppressor in glioblastoma: An integrated analysis., PMID:39319137
Microstructure of the cerebellum and its afferent pathways underpins dystonia in myoclonus dystonia., PMID:39254064
Mutation of mpv17 results in loss of iridophores due to mitochondrial dysfunction in tilapia., PMID:38946032
Systems Genetics Analyses Reveals Key Genes Related to Behavioral Traits in the Striatum of CFW Mice., PMID:38777602
BMP signaling maintains auricular chondrocyte identity and prevents microtia development by inhibiting protein kinase A., PMID:38690987
Deciphering the similarities and disparities of molecular mechanisms behind respiratory epithelium response to HCoV-229E and SARS-CoV-2 and drug repurposing, a systems biology approach., PMID:38652363
Structure of adenylyl cyclase 5 in complex with Gβγ offers insights into ADCY5-related dyskinesia., PMID:38589608
Elevated PDE4C level serves as a candidate diagnostic biomarker and correlates with poor survival in thyroid carcinoma., PMID:38514754
Genetic alterations in the neuronal development genes are associated with changes of the tumor immune microenvironment in pancreatic cancer., PMID:38495381
Investigating neuropathological changes and underlying neurobiological mechanisms in the early stages of primary blast-induced traumatic brain injury: Insights from a rat model., PMID:38373483
ADCY5-related dyskinesia - case series with literature review., PMID:38230756
Identification and characterization of biomarkers associated with endoplasmic reticulum protein processing in cerebral ischemia-reperfusion injury., PMID:38188159
Diverse WGBS profiles of longissimus dorsi muscle in Hainan black goats and hybrid goats., PMID:38097986
Case report: Diagnosis of ADCY5-related dyskinesia explaining the entire phenotype in a patient with atypical citrullinemia type I., PMID:38020658
Whole exome sequencing and clinical investigation of young onset dystonia: What can we learn?, PMID:37607452
Scoping Review on ADCY5-Related Movement Disorders., PMID:37476318
Exploring the common pathogenesis of Alzheimer's disease and type 2 diabetes mellitus via microarray data analysis., PMID:36923118
Screening the effective components in treating dampness stagnancy due to spleen deficiency syndrome and elucidating the potential mechanism of Poria water extract., PMID:36871985
Expanding the genotype-phenotype landscape of PDE10A-associated movement disorders., PMID:36805523
Requirement of Zebrafish Adcy3a and Adcy5 in Melanosome Dispersion and Melanocyte Stripe Formation., PMID:36430661
Enhanced drug delivery by a prodrug approach effectively relieves neuroinflammation in mice., PMID:36257461
Association of MARC1, ADCY5, and BCO1 Variants with the Lipid Profile, Suggests an Additive Effect for Hypertriglyceridemia in Mexican Adult Men., PMID:36233117
Elective and Emergency Deep Brain Stimulation in Refractory Pediatric Monogenetic Movement Disorders Presenting with Dystonia: Current Practice Illustrated by Two Cases., PMID:36223877
Fever-Induced and Early Morning Paroxysmal Dyskinesia in a Man With GNB1 Encephalopathy., PMID:36118517
ADCY5 gene mutation: a case report., PMID:36112278
The Genetic Landscape of Complex Childhood-Onset Hyperkinetic Movement Disorders., PMID:36054588
Motor, epileptic, and developmental phenotypes in genetic disorders affecting G protein coupled receptors-cAMP signaling., PMID:36003298
Valerian essential oil for treating insomnia via the serotonergic synapse pathway., PMID:35990355
Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program., PMID:35902682
A promising drug combination of mangiferin and glycyrrhizic acid ameliorates disease severity of rheumatoid arthritis by reversing the disturbance of thermogenesis and energy metabolism., PMID:35749826
Type 2 diabetes is more closely associated with risk of colorectal cancer based on elevated DNA methylation levels of ADCY5., PMID:35720494
Gene expression signatures of individual ductal carcinoma in situ lesions identify processes and biomarkers associated with progression towards invasive ductal carcinoma., PMID:35697697
Loss of CHGA Protein as a Potential Biomarker for Colon Cancer Diagnosis: A Study on Biomarker Discovery by Machine Learning and Confirmation by Immunohistochemistry in Colorectal Cancer Tissue Microarrays., PMID:35681650
PRKCB is relevant to prognosis of lung adenocarcinoma through methylation and immune infiltration., PMID:35567329
Construction of endogenous RNA regulatory network for colorectal cancer based on bioinformatics., PMID:35545337
Efficacy of Caffeine in ADCY5-Related Dyskinesia: A Retrospective Study., PMID:35384065
Mutation of ADCY5 gene in patients with Meige syndrome., PMID:35288007
A Clinical and Integrated Genetic Study of Isolated and Combined Dystonia in Taiwan., PMID:35041927
Transcriptome profiling of lncRNA and co-expression network in the vaginal epithelial tissue of women with lubrication disorders., PMID:34824921
Targeting adipocytic discoidin domain receptor 2 impedes fat gain while increasing bone mass., PMID:34645939
Identification of hub genes and functional modules in colon adenocarcinoma based on public databases by bioinformatics analysis., PMID:34532115
For research use only. Not for human or drug use.
