Catalog No.
YHB57901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Leu247
Predicted molecular weight
30.72 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95232
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Luc7-like protein 3, Luc7A, CREAP-1, CRE-associated protein 1, CREAP1, CROP, Okadaic acid-inducible phosphoprotein OA48-18, LUC7L3, O48, Cisplatin resistance-associated-overexpressed protein, cAMP regulatory element-associated protein 1
LUC7 proteins define two major classes of 5' splice sites in animals and plants., PMID:39979239
Alternative splicing regulation by tumor suppressing subtransferable candidate 4: a pathway to tumor suppression., PMID:39697342
The NEDD4-binding protein N4BP1 degrades mRNA substrates through the coding sequence independent of nonsense-mediated decay., PMID:39491646
Conserved role for spliceosomal component PRPF40A in microexon splicing., PMID:39389624
RBM25 depletion suppresses the growth of colon cancer cells through regulating alternative splicing of MNK2., PMID:39110401
Proteomics Identifies LUC7L3 as a Prognostic Biomarker for Hepatocellular Carcinoma., PMID:38785515
Functional analysis of the zinc finger modules of the Saccharomyces cerevisiae splicing factor Luc7., PMID:38719745
LUC7L3 is a downstream factor of SRSF1 and prevents genomic instability., PMID:38590928
Functional Analysis of the Zinc Finger Modules of the S. cerevisiae Splicing Factor Luc7., PMID:38352541
Screening and Identifying Reference Genes for Erythrocyte Production from Cord Blood CD34+ Cells Exposed to Hypoxia., PMID:38011643
Alternative splicing of BCL-x is controlled by RBM25 binding to a G-quadruplex in BCL-x pre-mRNA., PMID:37811881
Identification of bicalutamide resistance-related genes and prognosis prediction in patients with prostate cancer., PMID:37143720
Swelling-induced upregulation of miR-141-3p inhibits hepatocyte proliferation., PMID:35287291
Posttranscriptional Regulation of the Human LDL Receptor by the U2-Spliceosome., PMID:34809444
Phosphorylation regulates arginine-rich RNA-binding protein solubility and oligomerization., PMID:34673031
Identifying a possible new target for diagnosis and treatment of postmenopausal osteoporosis through bioinformatics and clinical sample analysis., PMID:34430595
Alternative splicing acts as an independent prognosticator in ovarian carcinoma., PMID:34001978
Functional analyses of human LUC7-like proteins involved in splicing regulation and myeloid neoplasms., PMID:33852859
Prognostic alternative splicing regulatory network of RBM25 in hepatocellular carcinoma., PMID:33830865
MiR-370-5p inhibits the progression of breast cancer via targeting LUC7L3., PMID:32972267
Peripheral blood transcriptome identifies high-risk benign and malignant breast lesions., PMID:32497068
Middle-Down Proteomics Reveals Dense Sites of Methylation and Phosphorylation in Arginine-Rich RNA-Binding Proteins., PMID:31994892
Systematic profiling of alternative splicing events and splicing factors in left- and right-sided colon cancer., PMID:31586988
Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription., PMID:31251911
Identification of Temporal Characteristic Networks of Peripheral Blood Changes in Alzheimer's Disease Based on Weighted Gene Co-expression Network Analysis., PMID:31178714
The splicing factor RBM25 controls MYC activity in acute myeloid leukemia., PMID:30635567
NEAT1-TFE3 and KAT6A-TFE3 renal cell carcinomas, new members of MiT family translocation renal cell carcinoma., PMID:30622287
Dysregulation of p53-RBM25-mediated circAMOTL1L biogenesis contributes to prostate cancer progression through the circAMOTL1L-miR-193a-5p-Pcdha pathway., PMID:30531834
RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease., PMID:29802200
Analysis of psoriasis-relevant gene expression and exon usage alterations after silencing of SR-rich splicing regulators., PMID:29512856
Structural Mechanism of the Oxygenase JMJD6 Recognition by the Extraterminal (ET) Domain of BRD4., PMID:29176719
RBM25 is a global splicing factor promoting inclusion of alternatively spliced exons and is itself regulated by lysine mono-methylation., PMID:28655759
Splicing factors differentially expressed in psoriasis alter mRNA maturation of disease-associated EDA+ fibronectin., PMID:28589370
LUC7L3/CROP inhibits replication of hepatitis B virus via suppressing enhancer II/basal core promoter activity., PMID:27857158
Jumonji domain containing protein 6 (Jmjd6) modulates splicing and specifically interacts with arginine-serine-rich (RS) domains of SR- and SR-like proteins., PMID:24914048
Next-generation sequencing of translocation renal cell carcinoma reveals novel RNA splicing partners and frequent mutations of chromatin-remodeling genes., PMID:24899691
Crystal structure and functional characterization of the human RBM25 PWI domain and its flanking basic region., PMID:23190262
Whole blood transcriptome correlates with treatment response in nasopharyngeal carcinoma., PMID:22986368
RBM25/LUC7L3 function in cardiac sodium channel splicing regulation of human heart failure., PMID:22939879
Role of RBM25/LUC7L3 in abnormal cardiac sodium channel splicing regulation in human heart failure., PMID:21859973
Novel splicing factor RBM25 modulates Bcl-x pre-mRNA 5' splice site selection., PMID:18663000
The U1 snRNP-associated factor Luc7p affects 5' splice site selection in yeast and human., PMID:17726058
Identification and characterization of RED120: a conserved PWI domain protein with links to splicing and 3'-end formation., PMID:17560998
A novel SR-related protein is required for the second step of Pre-mRNA splicing., PMID:15798186
Effect of cisplatin treatment on speckled distribution of a serine/arginine-rich nuclear protein CROP/Luc7A., PMID:12565863
Identification of okadaic-acid-induced genes by mRNA differential display in glioma cells., PMID:10754390
CROP/Luc7A, a novel serine/arginine-rich nuclear protein, isolated from cisplatin-resistant cell line., PMID:10631324
For research use only. Not for human or drug use.
