Please ensure Javascript is enabled for purposes of website accessibility
Home / Products / Recombinant Protein / Other Proteins

Recombinant Human ERLIN2 Protein, N-His

Catalog #:   YHB47901 Specific References (49) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: O94905
Protein length: Pro47-Asn339
Overview

Catalog No.

YHB47901

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Pro47-Asn339

Predicted molecular weight

35.46 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

O94905

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

Erlin-2, Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2, SPFH domain-containing protein 2, ERLIN2, Endoplasmic reticulum lipid raft-associated protein 2, C8orf2, SPFH2

Data Image
  • SDS-PAGE
    SDS PAGE for recombinant Human ERLIN2 protein
References

Genome-wide association studies of the fatty acid composition of Korean native chicken breast meat., PMID:40264524

Biallelic variants in ERLIN1: a series of 13 individuals with spastic paraparesis., PMID:39367212

The erlin1/erlin2 complex binds to and stabilizes phosphatidylinositol 3-phosphate and regulates autophagy., PMID:39018973

ERLIN1/2 scaffolds bridge TMUB1 and RNF170 and restrict cholesterol esterification to regulate the secretory pathway., PMID:38782601

Endoplasmic reticulum stress-related genes as prognostic and immunogenic biomarkers in prostate cancer., PMID:38643190

Expanding SPG18 clinical spectrum: autosomal dominant mutation causes complicated hereditary spastic paraplegia in a large family., PMID:38607533

Hereditary spastic paraparesis type 18 (SPG18): new ERLIN2 variants in a series of Italian patients, shedding light upon genetic and phenotypic variability., PMID:38427163

Novel ERLIN2 variant expands the phenotype of Spastic Paraplegia 18., PMID:38159148

KCNN1 promotes proliferation and metastasis of breast cancer via ERLIN2-mediated stabilization and K63-dependent ubiquitination of Cyclin B1., PMID:37831636

A novel autosomal dominant ERLIN2 variant activates endoplasmic reticulum stress in a Chinese HSP family., PMID:37752894

A case report of concurrent occurrence of two inherited axonopathies within a family: the benefit of whole-exome sequencing., PMID:37712628

Usp25-Erlin1/2 activity limits cholesterol flux to restrict virus infection., PMID:37683630

Inhibiting sorting nexin 10 promotes mucosal healing through SREBP2-mediated stemness restoration of intestinal stem cells., PMID:37647408

Disruption of Intracellular Calcium Homeostasis Leads to ERLIN2-Linked Hereditary Spastic Paraplegia in Patient-Derived Stem Cell Models., PMID:40225166

Rhomboid protease RHBDL4 promotes retrotranslocation of aggregation-prone proteins for degradation., PMID:35947953

Binding of the erlin1/2 complex to the third intralumenal loop of IP3R1 triggers its ubiquitin-proteasomal degradation., PMID:35568199

Identification of epilepsy concomitant candidate genes recognized in Saudi epileptic patients., PMID:35363364

Phenoconversion from Spastic Paraplegia to ALS/FTD Associated with CYP7B1 Compound Heterozygous Mutations., PMID:34946825

Role of ERLINs in the Control of Cell Fate through Lipid Rafts., PMID:34572057

Novel monoallelic variant in ERLIN2 causes spastic paraplegia converted to amyotrophic lateral sclerosis., PMID:34536826

EVI/WLS function is regulated by ubiquitylation and is linked to ER-associated degradation by ERLIN2., PMID:34406391

14-3-3 and erlin proteins differentially interact with RIPK2 complexes., PMID:34152391

Identification of Biomarkers Related to CD8+ T Cell Infiltration With Gene Co-expression Network in Lung Squamous Cell Carcinoma., PMID:33816462

Molecular and Immune Characteristics for Lung Adenocarcinoma Patients With ERLIN2 Overexpression., PMID:33424830

Genomic Characteristics and Selection Signatures in Indigenous Chongming White Goat (Capra hircus)., PMID:32973871

Genomic and Epigenomic Landscaping Defines New Therapeutic Targets for Adenosquamous Carcinoma of the Pancreas., PMID:32928922

SNHG17 drives malignant behaviors in astrocytoma by targeting miR-876-5p/ERLIN2 axis., PMID:32883232

Expansion of the genetic landscape of ERLIN2-related disorders., PMID:32147972

An autosomal dominant ERLIN2 mutation leads to a pure HSP phenotype distinct from the autosomal recessive ERLIN2 mutations (SPG18)., PMID:32094424

Proteomic Changes in Human Sperm During Sequential in vitro Capacitation and Acrosome Reaction., PMID:31824947

Bi-allelic variants in RNF170 are associated with hereditary spastic paraplegia., PMID:31636353

Palmitoylation of Hepatitis C Virus NS2 Regulates Its Subcellular Localization and NS2-NS3 Autocleavage., PMID:31597774

Exome Sequencing Identifies a Mutation (Y740C) in Spastic Paraplegia 7 Gene Associated with Adult-Onset Primary Lateral Sclerosis in a Chinese Family., PMID:31117107

The erlin2 T65I mutation inhibits erlin1/2 complex-mediated inositol 1,4,5-trisphosphate receptor ubiquitination and phosphatidylinositol 3-phosphate binding., PMID:30135210

MiR-410 Acts as a Tumor Suppressor in Estrogen Receptor-Positive Breast Cancer Cells by Directly Targeting ERLIN2 via the ERS Pathway., PMID:30016800

A novel heterozygous variant in ERLIN2 causes autosomal dominant pure hereditary spastic paraplegia., PMID:29528531

ERLIN1 mutations cause teenage-onset slowly progressive ALS in a large Turkish pedigree., PMID:29453415

MicroRNA-7 mediates cross-talk between metabolic signaling pathways in the liver., PMID:29321595

Associating transcription factors and conserved RNA structures with gene regulation in the human brain., PMID:28720872

Regulated Erlin-dependent release of the B12 transmembrane J-protein promotes ER membrane penetration of a non-enveloped virus., PMID:28614383

Identification of commonly altered genes between in major depressive disorder and a mouse model of depression., PMID:28596527

Novel Mutations in Endoplasmic Reticulum Lipid Raft-associated Protein 2 Gene Cause Pure Hereditary Spastic Paraplegia Type 18., PMID:27824013

The stromal cell-surface protease fibroblast activation protein-α localizes to lipid rafts and is recruited to invadopodia., PMID:26209915

The critical role of membralin in postnatal motor neuron survival and disease., PMID:25977983

A novel ER-microtubule-binding protein, ERLIN2, stabilizes Cyclin B1 and regulates cell cycle progression., PMID:27462423

Arsenite-induced changes in hepatic protein abundance in cynomolgus monkeys (Macaca fascicularis)., PMID:24866292

Proteomic analysis of detergent resistant membrane domains during early interaction of macrophages with rough and smooth Brucella melitensis., PMID:24643124

Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis., PMID:24217618

Hereditary spastic paraplegia: clinico-pathologic features and emerging molecular mechanisms., PMID:23897027

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

Contact Information

Order: order@antibodysystem.com

Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

Need help with your order?

Find out more about placing an order here

Recombinant Human ERLIN2 Protein, N-His [YHB47901]
Terms of sale Website terms of use Cookie policy Privacy
Copyright © 2025 AntibodySystem SAS. All Rights Reserved.            All Products are for Research Use Only