Catalog No.
YHB44301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala8-Thr210
Predicted molecular weight
24.26 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O94811
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
25 kDa brain-specific protein, TPPP/p25, Tubulin polymerization-promoting protein, p24, p25-alpha, TPPP, TPPP1
Establishment and characterization of Cri Du Chat neuronal stem cells: a novel promising resource to study the syndrome., PMID:40343585
Tubulin Polymerization Promoting Proteins: Functional Diversity With Implications in Neurological Disorders., PMID:40317801
Carbamazepine-exposed earthworms are characterized by tissue-specific accumulation patterns and transcriptional profiles., PMID:40117686
Synthesis, Physicochemical Properties and Anti-Fungal Activities of New Meso-Arylporphyrins., PMID:40076639
Structure of the ciliary tip central pair reveals the unique role of the microtubule-seam binding protein SPEF1., PMID:39677611
Pelophen B is a non-taxoid binding microtubule-stabilizing agent with promising preclinical anticancer properties., PMID:39633082
Theoretical guiding with molecular docking for the screening of high-sensitive AIE probes for specific protein detection., PMID:39515048
De Novo Rational Design of Peptide-Based Protein-Protein Inhibitors (Pep-PPIs) Approach by Mapping the Interaction Motifs of the PP Interface and Physicochemical Filtration: A Case on p25-Cdk5-Mediated Neurodegenerative Diseases., PMID:39148280
The Role of Tubulin Polymerization-Promoting Protein2 (TPPP2) in Spermatogenesis: A Narrative Review., PMID:39000129
Regulatable assembly of synthetic microtubule architectures using engineered microtubule-associated protein-IDR condensates., PMID:38992434
TPPP-BRD9 fusion-related gallbladder carcinomas are frequently associated with intracholecystic neoplasia, neuroendocrine carcinoma, and a distinctive small tubular-type adenocarcinoma commonly accompanied with a syringomatous pattern., PMID:38972607
SNCA and TPPP transcripts increase in oligodendroglial cytoplasmic inclusions in multiple system atrophy., PMID:38839023
Perspective Strategies for Interventions in Parkinsonism: Remedying the Neglected Role of TPPP., PMID:38391951
Regulatable assembly of synthetic microtubule architectures using engineered MAP-IDR condensates., PMID:38105997
Unveiling Potential Neurotoxic Mechansisms: Pb-Induced Activation of CDK5-p25 Signaling Axis in Alzheimer's Disease Development, Emphasizing CDK5 Inhibition and Formation of Toxic p25 Species., PMID:37968421
The Unicellular, Parasitic Fungi, Sanchytriomycota, Possess a DNA Sequence Possibly Encoding a Long Tubulin Polymerization Promoting Protein (TPPP) but Not a Fungal-Type One., PMID:37630588
Presence of p25alpha-Domain in Seed Plants (Spermatophyta): Microbial/Animal Contaminations and/or Orthologs., PMID:37629521
In vivo impact of tubulin polymerization promoting protein (Tppp) knockout to the airway inflammatory response., PMID:37507487
Meta-analysis of Transcriptomic Data from Lung Autopsy and Cellular Models of SARS-CoV-2 Infection., PMID:37486510
p25alpha Domain-Containing Proteins of Apicomplexans and Related Taxa., PMID:37375031
Identifying mRNAs Residing in Myelinating Oligodendrocyte Processes as a Basis for Understanding Internode Autonomy., PMID:37109474
Tubulin Polymerization Promoting Proteins (TPPPs) of Aphelidiomycota: Correlation between the Incidence of p25alpha Domain and the Eukaryotic Flagellum., PMID:36983544
Somatic SNCA Copy Number Variants in Multiple System Atrophy are Related to Pathology and Inclusions., PMID:36448620
On the TPPP Protein of the Enigmatic Fungus, Olpidium-Correlation between the Incidence of p25alpha Domain and That of the Eukaryotic Flagellum., PMID:36430412
In vitro study of ochratoxin A in the expression of genes associated with neuron survival and viability., PMID:36400265
Early and extensive alterations of glial connexins, distal oligodendrogliopathy type demyelination, and nodal/paranodal pathology are characteristic of multiple system atrophy., PMID:36368713
Modulatory Role of TPPP3 in Microtubule Organization and Its Impact on Alpha-Synuclein Pathology., PMID:36230985
α-synuclein buildup is alleviated via ESCRT-dependent endosomal degradation brought about by p38MAPK inhibition in cells expressing p25α., PMID:36162505
The circadian system in cystic fibrosis mice is regulated by histone deacetylase 6., PMID:36062879
Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies., PMID:35716955
Dynamic induction of the myelin-associated growth inhibitor Nogo-A in perilesional plasticity regions after human spinal cord injury., PMID:35698271
Autophagy mediates the clearance of oligodendroglial SNCA/alpha-synuclein and TPPP/p25A in multiple system atrophy models., PMID:35000546
Anti-Aggregative Effect of the Antioxidant DJ-1 on the TPPP/p25-Derived Pathological Associations of Alpha-Synuclein., PMID:34831132
Gain of TPPP as a predictor of progression in patients with bladder cancer., PMID:34584549
Prolyl oligopeptidase inhibition reduces alpha-synuclein aggregation in a cellular model of multiple system atrophy., PMID:34486218
Proteomic Analysis Unveils Expressional Changes in Cytoskeleton- and Synaptic Plasticity-Associated Proteins in Rat Brain Six Months after Withdrawal from Morphine., PMID:34357055
Drosophila tubulin polymerization promoting protein mutants reveal pathological correlates relevant to human Parkinson's disease., PMID:34193896
Prenatal Lead (Pb) Exposure and Peripheral Blood DNA Methylation (5mC) and Hydroxymethylation (5hmC) in Mexican Adolescents from the ELEMENT Birth Cohort., PMID:34152198
Truncated TPPP - An Endopterygota-specific protein., PMID:34136696
Co-Transmission of Alpha-Synuclein and TPPP/p25 Inhibits Their Proteolytic Degradation in Human Cell Models., PMID:34084775
Tubulin Polymerization Promoting Protein Affects the Circadian Timing System in C57Bl/6 Mice., PMID:34046074
Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential., PMID:33978813
On the TPPP-like proteins of flagellated fungi., PMID:33910677
Regulation of the tubulin polymerization-promoting protein by Ca2+/S100 proteins., PMID:33831707
SIRT1 decelerates morphological processing of oligodendrocyte cell lines and regulates the expression of cytoskeleton-related oligodendrocyte proteins., PMID:33556638
Characterization of the structure, vascularity, and stem/progenitor cell populations in porcine Achilles tendon (PAT)., PMID:33496880
The proteome of granulovacuolar degeneration and neurofibrillary tangles in Alzheimer's disease., PMID:33492460
Mining GWAS and eQTL data for CF lung disease modifiers by gene expression imputation., PMID:33253230
Fear Deficits in Hypomyelinated Tppp Knock-Out Mice., PMID:32878961
A high-content RNAi screen reveals multiple roles for long noncoding RNAs in cell division., PMID:32296040
For research use only. Not for human or drug use.
